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350 related items for PubMed ID: 22845665
1. Induction of P-glycoprotein and Bcrp at the rat blood-brain barrier following a subchronic morphine treatment is mediated through NMDA/COX-2 activation. Yousif S, Chaves C, Potin S, Margaill I, Scherrmann JM, Declèves X. J Neurochem; 2012 Nov; 123(4):491-503. PubMed ID: 22845665 [Abstract] [Full Text] [Related]
2. Effect of Subchronic Intravenous Morphine Infusion and Naloxone-Precipitated Morphine Withdrawal on P-gp and Bcrp at the Rat Blood-Brain Barrier. Chaves C, Gómez-Zepeda D, Auvity S, Menet MC, Crété D, Labat L, Remião F, Cisternino S, Declèves X. J Pharm Sci; 2016 Jan; 105(1):350-8. PubMed ID: 26554626 [Abstract] [Full Text] [Related]
3. Glutamate up-regulates P-glycoprotein expression in rat brain microvessel endothelial cells by an NMDA receptor-mediated mechanism. Zhu HJ, Liu GQ. Life Sci; 2004 Jul 30; 75(11):1313-22. PubMed ID: 15234189 [Abstract] [Full Text] [Related]
4. P-glycoprotein (MDR1/ABCB1) and breast cancer resistance protein (BCRP/ABCG2) restrict brain accumulation of the JAK1/2 inhibitor, CYT387. Durmus S, Xu N, Sparidans RW, Wagenaar E, Beijnen JH, Schinkel AH. Pharmacol Res; 2013 Oct 30; 76():9-16. PubMed ID: 23827160 [Abstract] [Full Text] [Related]
5. Quantitative evaluation of the impact of active efflux by p-glycoprotein and breast cancer resistance protein at the blood-brain barrier on the predictability of the unbound concentrations of drugs in the brain using cerebrospinal fluid concentration as a surrogate. Kodaira H, Kusuhara H, Fujita T, Ushiki J, Fuse E, Sugiyama Y. J Pharmacol Exp Ther; 2011 Dec 30; 339(3):935-44. PubMed ID: 21934030 [Abstract] [Full Text] [Related]
6. Kinetic analysis of the cooperation of P-glycoprotein (P-gp/Abcb1) and breast cancer resistance protein (Bcrp/Abcg2) in limiting the brain and testis penetration of erlotinib, flavopiridol, and mitoxantrone. Kodaira H, Kusuhara H, Ushiki J, Fuse E, Sugiyama Y. J Pharmacol Exp Ther; 2010 Jun 30; 333(3):788-96. PubMed ID: 20304939 [Abstract] [Full Text] [Related]
7. P-glycoprotein, breast cancer resistance protein, Organic Anion Transporter 3, and Transporting Peptide 1a4 during blood-brain barrier maturation: involvement of Wnt/β-catenin and endothelin-1 signaling. Harati R, Benech H, Villégier AS, Mabondzo A. Mol Pharm; 2013 May 06; 10(5):1566-80. PubMed ID: 22998451 [Abstract] [Full Text] [Related]
8. Effect of chronic exposure to morphine on the rat blood-brain barrier: focus on the P-glycoprotein. Yousif S, Saubaméa B, Cisternino S, Marie-Claire C, Dauchy S, Scherrmann JM, Declèves X. J Neurochem; 2008 Nov 06; 107(3):647-57. PubMed ID: 18761714 [Abstract] [Full Text] [Related]
9. P-glycoprotein and breast cancer resistance protein influence brain distribution of dasatinib. Chen Y, Agarwal S, Shaik NM, Chen C, Yang Z, Elmquist WF. J Pharmacol Exp Ther; 2009 Sep 06; 330(3):956-63. PubMed ID: 19491323 [Abstract] [Full Text] [Related]
12. Brain penetration of WEB 2086 (Apafant) and dantrolene in Mdr1a (P-glycoprotein) and Bcrp knockout rats. Fuchs H, Kishimoto W, Gansser D, Tanswell P, Ishiguro N. Drug Metab Dispos; 2014 Oct 06; 42(10):1761-5. PubMed ID: 25053619 [Abstract] [Full Text] [Related]
13. [¹¹C]befloxatone brain kinetics is not influenced by Bcrp function at the blood-brain barrier: a PET study using Bcrp TGEM knockout rats. Hosten B, Boisgard R, Jacob A, Goutal S, Saubaméa B, Dollé F, Scherrmann JM, Cisternino S, Tournier N. Eur J Pharm Sci; 2013 Nov 20; 50(3-4):520-5. PubMed ID: 23981334 [Abstract] [Full Text] [Related]
14. Differential regulation of transport proteins in the periinfarct region following reversible middle cerebral artery occlusion in rats. Dazert P, Suofu Y, Grube M, Popa-Wagner A, Kroemer HK, Jedlitschky G, Kessler C. Neuroscience; 2006 Nov 03; 142(4):1071-9. PubMed ID: 16997484 [Abstract] [Full Text] [Related]
15. P-glycoprotein and breast cancer resistance protein expression and function at the blood-brain barrier and blood-cerebrospinal fluid barrier (choroid plexus) in streptozotocin-induced diabetes in rats. Reichel V, Burghard S, John I, Huber O. Brain Res; 2011 Jan 25; 1370():238-45. PubMed ID: 21075088 [Abstract] [Full Text] [Related]
16. Cerebrospinal fluid can be used as a surrogate to assess brain exposures of breast cancer resistance protein and P-glycoprotein substrates. Xiao G, Black C, Hetu G, Sands E, Wang J, Caputo R, Rohde E, Gan LS. Drug Metab Dispos; 2012 Apr 25; 40(4):779-87. PubMed ID: 22266779 [Abstract] [Full Text] [Related]
17. Development and Validation of an In-Cell Western for Quantifying P-Glycoprotein Expression in Human Brain Microvascular Endothelial (hCMEC/D3) Cells. McInerney MP, Pan Y, Short JL, Nicolazzo JA. J Pharm Sci; 2017 Sep 25; 106(9):2614-2624. PubMed ID: 28065764 [Abstract] [Full Text] [Related]
18. ATP binding cassette transporters in two distinct compartments of the skin contribute to transdermal absorption of a typical substrate. Hashimoto N, Nakamichi N, Uwafuji S, Yoshida K, Sugiura T, Tsuji A, Kato Y. J Control Release; 2013 Jan 10; 165(1):54-61. PubMed ID: 23089896 [Abstract] [Full Text] [Related]