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259 related items for PubMed ID: 22851176

  • 1. Scaffold protein connector enhancer of kinase suppressor of Ras isoform 3 (CNK3) coordinates assembly of a multiprotein epithelial sodium channel (ENaC)-regulatory complex.
    Soundararajan R, Ziera T, Koo E, Ling K, Wang J, Borden SA, Pearce D.
    J Biol Chem; 2012 Sep 21; 287(39):33014-25. PubMed ID: 22851176
    [Abstract] [Full Text] [Related]

  • 2. The role of the ENaC-regulatory complex in aldosterone-mediated sodium transport.
    Soundararajan R, Pearce D, Ziera T.
    Mol Cell Endocrinol; 2012 Mar 24; 350(2):242-7. PubMed ID: 22101317
    [Abstract] [Full Text] [Related]

  • 3. Expression of ENaC, SGK1 and Nedd4 isoforms in the cochlea of guinea pig.
    Zhong SX, Hu GH, Liu ZH.
    Folia Histochem Cytobiol; 2014 Mar 24; 52(2):144-8. PubMed ID: 25007182
    [Abstract] [Full Text] [Related]

  • 4. Neural precursor cell-expressed developmentally down-regulated protein 4-2 (Nedd4-2) regulation by 14-3-3 protein binding at canonical serum and glucocorticoid kinase 1 (SGK1) phosphorylation sites.
    Chandran S, Li H, Dong W, Krasinska K, Adams C, Alexandrova L, Chien A, Hallows KR, Bhalla V.
    J Biol Chem; 2011 Oct 28; 286(43):37830-40. PubMed ID: 21900244
    [Abstract] [Full Text] [Related]

  • 5. COMMD1 downregulates the epithelial sodium channel through Nedd4-2.
    Ke Y, Butt AG, Swart M, Liu YF, McDonald FJ.
    Am J Physiol Renal Physiol; 2010 Jun 28; 298(6):F1445-56. PubMed ID: 20237237
    [Abstract] [Full Text] [Related]

  • 6. Interaction of serum- and glucocorticoid regulated kinase 1 (SGK1) with the WW-domains of Nedd4-2 is required for epithelial sodium channel regulation.
    Wiemuth D, Lott JS, Ly K, Ke Y, Teesdale-Spittle P, Snyder PM, McDonald FJ.
    PLoS One; 2010 Aug 13; 5(8):e12163. PubMed ID: 20730100
    [Abstract] [Full Text] [Related]

  • 7. Functional regulation of the epithelial Na+ channel by IkappaB kinase-beta occurs via phosphorylation of the ubiquitin ligase Nedd4-2.
    Edinger RS, Lebowitz J, Li H, Alzamora R, Wang H, Johnson JP, Hallows KR.
    J Biol Chem; 2009 Jan 02; 284(1):150-157. PubMed ID: 18981174
    [Abstract] [Full Text] [Related]

  • 8. Nedd4-2 modulates renal Na+-Cl- cotransporter via the aldosterone-SGK1-Nedd4-2 pathway.
    Arroyo JP, Lagnaz D, Ronzaud C, Vázquez N, Ko BS, Moddes L, Ruffieux-Daidié D, Hausel P, Koesters R, Yang B, Stokes JB, Hoover RS, Gamba G, Staub O.
    J Am Soc Nephrol; 2011 Sep 02; 22(9):1707-19. PubMed ID: 21852580
    [Abstract] [Full Text] [Related]

  • 9. Regulation of epithelial Na+ channels by aldosterone: role of Sgk1.
    Lee IH, Campbell CR, Cook DI, Dinudom A.
    Clin Exp Pharmacol Physiol; 2008 Feb 02; 35(2):235-41. PubMed ID: 18197893
    [Abstract] [Full Text] [Related]

  • 10. mTORC2 regulates renal tubule sodium uptake by promoting ENaC activity.
    Gleason CE, Frindt G, Cheng CJ, Ng M, Kidwai A, Rashmi P, Lang F, Baum M, Palmer LG, Pearce D.
    J Clin Invest; 2015 Jan 02; 125(1):117-28. PubMed ID: 25415435
    [Abstract] [Full Text] [Related]

  • 11. Aldosterone-induced serum and glucocorticoid-induced kinase 1 expression is accompanied by Nedd4-2 phosphorylation and increased Na+ transport in cortical collecting duct cells.
    Flores SY, Loffing-Cueni D, Kamynina E, Daidié D, Gerbex C, Chabanel S, Dudler J, Loffing J, Staub O.
    J Am Soc Nephrol; 2005 Aug 02; 16(8):2279-87. PubMed ID: 15958725
    [Abstract] [Full Text] [Related]

  • 12. Renal tubular SGK1 deficiency causes impaired K+ excretion via loss of regulation of NEDD4-2/WNK1 and ENaC.
    Al-Qusairi L, Basquin D, Roy A, Stifanelli M, Rajaram RD, Debonneville A, Nita I, Maillard M, Loffing J, Subramanya AR, Staub O.
    Am J Physiol Renal Physiol; 2016 Aug 01; 311(2):F330-42. PubMed ID: 27009335
    [Abstract] [Full Text] [Related]

  • 13. Proanthocyanidins block aldosterone-dependent up-regulation of cardiac gamma ENaC and Nedd4-2 inactivation via SGK1.
    Galiana-Simal A, Olivares-Álvaro E, Klett-Mingo M, Ruiz-Roso MB, Ballesteros S, de Las Heras N, Fuller PJ, Lahera V, Martín-Fernández B.
    J Nutr Biochem; 2016 Nov 01; 37():13-19. PubMed ID: 27592201
    [Abstract] [Full Text] [Related]

  • 14. Akt mediates the effect of insulin on epithelial sodium channels by inhibiting Nedd4-2.
    Lee IH, Dinudom A, Sanchez-Perez A, Kumar S, Cook DI.
    J Biol Chem; 2007 Oct 12; 282(41):29866-73. PubMed ID: 17715136
    [Abstract] [Full Text] [Related]

  • 15. Serum and glucocorticoid-induced kinase (SGK) 1 and the epithelial sodium channel are regulated by multiple with no lysine (WNK) family members.
    Heise CJ, Xu BE, Deaton SL, Cha SK, Cheng CJ, Earnest S, Sengupta S, Juang YC, Stippec S, Xu Y, Zhao Y, Huang CL, Cobb MH.
    J Biol Chem; 2010 Aug 13; 285(33):25161-7. PubMed ID: 20525693
    [Abstract] [Full Text] [Related]

  • 16. Epithelial sodium channel regulation by cell surface-associated serum- and glucocorticoid-regulated kinase 1.
    Thomas SV, Kathpalia PP, Rajagopal M, Charlton C, Zhang J, Eaton DC, Helms MN, Pao AC.
    J Biol Chem; 2011 Sep 16; 286(37):32074-85. PubMed ID: 21784856
    [Abstract] [Full Text] [Related]

  • 17. Serum- and glucocorticoid-regulated kinase 1 regulates ubiquitin ligase neural precursor cell-expressed, developmentally down-regulated protein 4-2 by inducing interaction with 14-3-3.
    Bhalla V, Daidié D, Li H, Pao AC, LaGrange LP, Wang J, Vandewalle A, Stockand JD, Staub O, Pearce D.
    Mol Endocrinol; 2005 Dec 16; 19(12):3073-84. PubMed ID: 16099816
    [Abstract] [Full Text] [Related]

  • 18. Genetic variations in the sodium balance-regulating genes ENaC, NEDD4L, NDFIP2 and USP2 influence blood pressure and hypertension.
    Jin HS, Hong KW, Lim JE, Hwang SY, Lee SH, Shin C, Park HK, Oh B.
    Kidney Blood Press Res; 2010 Dec 16; 33(1):15-23. PubMed ID: 20090362
    [Abstract] [Full Text] [Related]

  • 19. Epithelial sodium channel regulated by differential composition of a signaling complex.
    Soundararajan R, Melters D, Shih IC, Wang J, Pearce D.
    Proc Natl Acad Sci U S A; 2009 May 12; 106(19):7804-9. PubMed ID: 19380724
    [Abstract] [Full Text] [Related]

  • 20. AMP-activated kinase inhibits the epithelial Na+ channel through functional regulation of the ubiquitin ligase Nedd4-2.
    Bhalla V, Oyster NM, Fitch AC, Wijngaarden MA, Neumann D, Schlattner U, Pearce D, Hallows KR.
    J Biol Chem; 2006 Sep 08; 281(36):26159-69. PubMed ID: 16844684
    [Abstract] [Full Text] [Related]

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