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373 related items for PubMed ID: 22858649

  • 1. Bufalin increases sensitivity to AKT/mTOR-induced autophagic cell death in SK-HEP-1 human hepatocellular carcinoma cells.
    Tsai SC, Yang JS, Peng SF, Lu CC, Chiang JH, Chung JG, Lin MW, Lin JK, Amagaya S, Wai-Shan Chung C, Tung TT, Huang WW, Tseng MT.
    Int J Oncol; 2012 Oct; 41(4):1431-42. PubMed ID: 22858649
    [Abstract] [Full Text] [Related]

  • 2. Kaempferol induces autophagy through AMPK and AKT signaling molecules and causes G2/M arrest via downregulation of CDK1/cyclin B in SK-HEP-1 human hepatic cancer cells.
    Huang WW, Tsai SC, Peng SF, Lin MW, Chiang JH, Chiu YJ, Fushiya S, Tseng MT, Yang JS.
    Int J Oncol; 2013 Jun; 42(6):2069-77. PubMed ID: 23591552
    [Abstract] [Full Text] [Related]

  • 3. Bufalin induces G2/M phase arrest and triggers autophagy via the TNF, JNK, BECN-1 and ATG8 pathway in human hepatoma cells.
    Hsu CM, Tsai Y, Wan L, Tsai FJ.
    Int J Oncol; 2013 Jul; 43(1):338-48. PubMed ID: 23677253
    [Abstract] [Full Text] [Related]

  • 4. Arenobufagin, a natural bufadienolide from toad venom, induces apoptosis and autophagy in human hepatocellular carcinoma cells through inhibition of PI3K/Akt/mTOR pathway.
    Zhang DM, Liu JS, Deng LJ, Chen MF, Yiu A, Cao HH, Tian HY, Fung KP, Kurihara H, Pan JX, Ye WC.
    Carcinogenesis; 2013 Jun; 34(6):1331-42. PubMed ID: 23393227
    [Abstract] [Full Text] [Related]

  • 5. Bufotalin from Venenum Bufonis inhibits growth of multidrug resistant HepG2 cells through G2/M cell cycle arrest and apoptosis.
    Zhang DM, Liu JS, Tang MK, Yiu A, Cao HH, Jiang L, Chan JY, Tian HY, Fung KP, Ye WC.
    Eur J Pharmacol; 2012 Oct 05; 692(1-3):19-28. PubMed ID: 22841670
    [Abstract] [Full Text] [Related]

  • 6. Anticancer effects of bufalin on human hepatocellular carcinoma HepG2 cells: roles of apoptosis and autophagy.
    Miao Q, Bi LL, Li X, Miao S, Zhang J, Zhang S, Yang Q, Xie YH, Zhang J, Wang SW.
    Int J Mol Sci; 2013 Jan 11; 14(1):1370-82. PubMed ID: 23344047
    [Abstract] [Full Text] [Related]

  • 7. Inhibitory effect of oleanolic acid on hepatocellular carcinoma via ERK-p53-mediated cell cycle arrest and mitochondrial-dependent apoptosis.
    Wang X, Bai H, Zhang X, Liu J, Cao P, Liao N, Zhang W, Wang Z, Hai C.
    Carcinogenesis; 2013 Jun 11; 34(6):1323-30. PubMed ID: 23404993
    [Abstract] [Full Text] [Related]

  • 8. Blocking autophagy enhances the apoptosis effect of bufalin on human hepatocellular carcinoma cells through endoplasmic reticulum stress and JNK activation.
    Hu F, Han J, Zhai B, Ming X, Zhuang L, Liu Y, Pan S, Liu T.
    Apoptosis; 2014 Jan 11; 19(1):210-23. PubMed ID: 24114361
    [Abstract] [Full Text] [Related]

  • 9. AKT serine/threonine protein kinase modulates baicalin-triggered autophagy in human bladder cancer T24 cells.
    Lin C, Tsai SC, Tseng MT, Peng SF, Kuo SC, Lin MW, Hsu YM, Lee MR, Amagaya S, Huang WW, Wu TS, Yang JS.
    Int J Oncol; 2013 Mar 11; 42(3):993-1000. PubMed ID: 23354080
    [Abstract] [Full Text] [Related]

  • 10. The selective Hsp90 inhibitor BJ-B11 exhibits potent antitumor activity via induction of cell cycle arrest, apoptosis and autophagy in Eca-109 human esophageal squamous carcinoma cells.
    Liu KS, Zhang Y, Ding WC, Wang SX, Xiang YF, Yang P, Chen ZP, Zheng K, Liu Z, Xia M, Wang YF.
    Int J Oncol; 2012 Dec 11; 41(6):2276-84. PubMed ID: 23076967
    [Abstract] [Full Text] [Related]

  • 11. Bufalin suppresses hepatocellular carcinoma invasion and metastasis by targeting HIF-1α via the PI3K/AKT/mTOR pathway.
    Wang H, Zhang C, Xu L, Zang K, Ning Z, Jiang F, Chi H, Zhu X, Meng Z.
    Oncotarget; 2016 Apr 12; 7(15):20193-208. PubMed ID: 26958938
    [Abstract] [Full Text] [Related]

  • 12. Hellebrigenin induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells through inhibition of Akt.
    Deng LJ, Hu LP, Peng QL, Yang XL, Bai LL, Yiu A, Li Y, Tian HY, Ye WC, Zhang DM.
    Chem Biol Interact; 2014 Aug 05; 219():184-94. PubMed ID: 24954031
    [Abstract] [Full Text] [Related]

  • 13. The biological role of autophagy in regulating and controlling the proliferation of liver cancer cells induced by bufalin.
    Sheng X, Zhu P, Qin J, Li Q.
    Oncol Rep; 2018 Jun 05; 39(6):2931-2941. PubMed ID: 29658591
    [Abstract] [Full Text] [Related]

  • 14. AKT serine/threonine protein kinase modulates bufalin-triggered intrinsic pathway of apoptosis in CAL 27 human oral cancer cells.
    Tsai SC, Lu CC, Lee CY, Lin YC, Chung JG, Kuo SC, Amagaya S, Chen FN, Chen MY, Chan SF, Yang JS.
    Int J Oncol; 2012 Nov 05; 41(5):1683-92. PubMed ID: 22922805
    [Abstract] [Full Text] [Related]

  • 15. Bufalin Reverses Resistance to Sorafenib by Inhibiting Akt Activation in Hepatocellular Carcinoma: The Role of Endoplasmic Reticulum Stress.
    Zhai B, Hu F, Yan H, Zhao D, Jin X, Fang T, Pan S, Sun X, Xu L.
    PLoS One; 2015 Nov 05; 10(9):e0138485. PubMed ID: 26381511
    [Abstract] [Full Text] [Related]

  • 16. Coptisine induces autophagic cell death through down-regulation of PI3K/Akt/mTOR signaling pathway and up-regulation of ROS-mediated mitochondrial dysfunction in hepatocellular carcinoma Hep3B cells.
    Kim SY, Hwangbo H, Kim MY, Ji SY, Lee H, Kim GY, Kwon CY, Leem SH, Hong SH, Cheong J, Choi YH.
    Arch Biochem Biophys; 2021 Jan 15; 697():108688. PubMed ID: 33227289
    [Abstract] [Full Text] [Related]

  • 17. [IL-12 induces autophagy via AKT/mTOR/STAT3 signaling pathway in human hepatoma cells].
    Liu C, Xie C, Lin Y, Wu B, Wang Q, Li Z, Tu Z.
    Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi; 2016 Jul 15; 32(7):870-5. PubMed ID: 27363263
    [Abstract] [Full Text] [Related]

  • 18. Bufalin induces G0/G1 phase arrest through inhibiting the levels of cyclin D, cyclin E, CDK2 and CDK4, and triggers apoptosis via mitochondrial signaling pathway in T24 human bladder cancer cells.
    Huang WW, Yang JS, Pai SJ, Wu PP, Chang SJ, Chueh FS, Fan MJ, Chiou SM, Kuo HM, Yeh CC, Chen PY, Tsuzuki M, Chung JG.
    Mutat Res; 2012 Apr 01; 732(1-2):26-33. PubMed ID: 22285700
    [Abstract] [Full Text] [Related]

  • 19. HS-116, a novel phosphatidylinositol 3-kinase inhibitor induces apoptosis and suppresses angiogenesis of hepatocellular carcinoma through inhibition of the PI3K/AKT/mTOR pathway.
    Jung KH, Choi MJ, Hong S, Lee H, Hong SW, Zheng HM, Lee HS, Hong S, Hong SS.
    Cancer Lett; 2012 Mar 28; 316(2):187-95. PubMed ID: 22182943
    [Abstract] [Full Text] [Related]

  • 20. Investigation of prunetrin induced G2/M cell cycle arrest and apoptosis via Akt/mTOR/MAPK pathways in hepatocellular carcinoma cells.
    Abusaliya A, Bhosale PB, Kim HH, Park MY, Jeong SH, Lee S, Kim GS.
    Biomed Pharmacother; 2024 May 28; 174():116483. PubMed ID: 38552440
    [Abstract] [Full Text] [Related]

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