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Journal Abstract Search

1120 related items for PubMed ID: 22878233

  • 1. Mitochondrial fission induces glycolytic reprogramming in cancer-associated myofibroblasts, driving stromal lactate production, and early tumor growth.
    Guido C, Whitaker-Menezes D, Lin Z, Pestell RG, Howell A, Zimmers TA, Casimiro MC, Aquila S, Ando' S, Martinez-Outschoorn UE, Sotgia F, Lisanti MP.
    Oncotarget; 2012 Aug; 3(8):798-810. PubMed ID: 22878233
    [Abstract] [Full Text] [Related]

  • 2. Metabolic reprogramming of cancer-associated fibroblasts by TGF-β drives tumor growth: connecting TGF-β signaling with "Warburg-like" cancer metabolism and L-lactate production.
    Guido C, Whitaker-Menezes D, Capparelli C, Balliet R, Lin Z, Pestell RG, Howell A, Aquila S, Andò S, Martinez-Outschoorn U, Sotgia F, Lisanti MP.
    Cell Cycle; 2012 Aug 15; 11(16):3019-35. PubMed ID: 22874531
    [Abstract] [Full Text] [Related]

  • 3. Mitochondrial oxidative stress in cancer-associated fibroblasts drives lactate production, promoting breast cancer tumor growth: understanding the aging and cancer connection.
    Balliet RM, Capparelli C, Guido C, Pestell TG, Martinez-Outschoorn UE, Lin Z, Whitaker-Menezes D, Chiavarina B, Pestell RG, Howell A, Sotgia F, Lisanti MP.
    Cell Cycle; 2011 Dec 01; 10(23):4065-73. PubMed ID: 22129993
    [Abstract] [Full Text] [Related]

  • 4. Tumor microenvironment and metabolic synergy in breast cancers: critical importance of mitochondrial fuels and function.
    Martinez-Outschoorn U, Sotgia F, Lisanti MP.
    Semin Oncol; 2014 Apr 01; 41(2):195-216. PubMed ID: 24787293
    [Abstract] [Full Text] [Related]

  • 5. Hyperactivation of oxidative mitochondrial metabolism in epithelial cancer cells in situ: visualizing the therapeutic effects of metformin in tumor tissue.
    Whitaker-Menezes D, Martinez-Outschoorn UE, Flomenberg N, Birbe RC, Witkiewicz AK, Howell A, Pavlides S, Tsirigos A, Ertel A, Pestell RG, Broda P, Minetti C, Lisanti MP, Sotgia F.
    Cell Cycle; 2011 Dec 01; 10(23):4047-64. PubMed ID: 22134189
    [Abstract] [Full Text] [Related]

  • 6. Metabolic remodeling of the tumor microenvironment: migration stimulating factor (MSF) reprograms myofibroblasts toward lactate production, fueling anabolic tumor growth.
    Carito V, Bonuccelli G, Martinez-Outschoorn UE, Whitaker-Menezes D, Caroleo MC, Cione E, Howell A, Pestell RG, Lisanti MP, Sotgia F.
    Cell Cycle; 2012 Sep 15; 11(18):3403-14. PubMed ID: 22918248
    [Abstract] [Full Text] [Related]

  • 7. Cigarette smoke metabolically promotes cancer, via autophagy and premature aging in the host stromal microenvironment.
    Salem AF, Al-Zoubi MS, Whitaker-Menezes D, Martinez-Outschoorn UE, Lamb R, Hulit J, Howell A, Gandara R, Sartini M, Galbiati F, Bevilacqua G, Sotgia F, Lisanti MP.
    Cell Cycle; 2013 Mar 01; 12(5):818-25. PubMed ID: 23388463
    [Abstract] [Full Text] [Related]

  • 8. Pyruvate kinase expression (PKM1 and PKM2) in cancer-associated fibroblasts drives stromal nutrient production and tumor growth.
    Chiavarina B, Whitaker-Menezes D, Martinez-Outschoorn UE, Witkiewicz AK, Birbe R, Howell A, Pestell RG, Smith J, Daniel R, Sotgia F, Lisanti MP.
    Cancer Biol Ther; 2011 Dec 15; 12(12):1101-13. PubMed ID: 22236875
    [Abstract] [Full Text] [Related]

  • 9. Energy transfer in "parasitic" cancer metabolism: mitochondria are the powerhouse and Achilles' heel of tumor cells.
    Martinez-Outschoorn UE, Pestell RG, Howell A, Tykocinski ML, Nagajyothi F, Machado FS, Tanowitz HB, Sotgia F, Lisanti MP.
    Cell Cycle; 2011 Dec 15; 10(24):4208-16. PubMed ID: 22033146
    [Abstract] [Full Text] [Related]

  • 10. Cancer cells metabolically "fertilize" the tumor microenvironment with hydrogen peroxide, driving the Warburg effect: implications for PET imaging of human tumors.
    Martinez-Outschoorn UE, Lin Z, Trimmer C, Flomenberg N, Wang C, Pavlides S, Pestell RG, Howell A, Sotgia F, Lisanti MP.
    Cell Cycle; 2011 Aug 01; 10(15):2504-20. PubMed ID: 21778829
    [Abstract] [Full Text] [Related]

  • 11. Stromal-epithelial metabolic coupling in cancer: integrating autophagy and metabolism in the tumor microenvironment.
    Martinez-Outschoorn UE, Pavlides S, Howell A, Pestell RG, Tanowitz HB, Sotgia F, Lisanti MP.
    Int J Biochem Cell Biol; 2011 Jul 01; 43(7):1045-51. PubMed ID: 21300172
    [Abstract] [Full Text] [Related]

  • 12. Compartment-specific activation of PPARγ governs breast cancer tumor growth, via metabolic reprogramming and symbiosis.
    Avena P, Anselmo W, Whitaker-Menezes D, Wang C, Pestell RG, Lamb RS, Hulit J, Casaburi I, Andò S, Martinez-Outschoorn UE, Lisanti MP, Sotgia F.
    Cell Cycle; 2013 May 01; 12(9):1360-70. PubMed ID: 23574724
    [Abstract] [Full Text] [Related]

  • 13. Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis via glycolysis and ketone production.
    Capparelli C, Guido C, Whitaker-Menezes D, Bonuccelli G, Balliet R, Pestell TG, Goldberg AF, Pestell RG, Howell A, Sneddon S, Birbe R, Tsirigos A, Martinez-Outschoorn U, Sotgia F, Lisanti MP.
    Cell Cycle; 2012 Jun 15; 11(12):2285-302. PubMed ID: 22684298
    [Abstract] [Full Text] [Related]

  • 14. Two-compartment tumor metabolism: autophagy in the tumor microenvironment and oxidative mitochondrial metabolism (OXPHOS) in cancer cells.
    Salem AF, Whitaker-Menezes D, Lin Z, Martinez-Outschoorn UE, Tanowitz HB, Al-Zoubi MS, Howell A, Pestell RG, Sotgia F, Lisanti MP.
    Cell Cycle; 2012 Jul 01; 11(13):2545-56. PubMed ID: 22722266
    [Abstract] [Full Text] [Related]

  • 15. Ethanol exposure induces the cancer-associated fibroblast phenotype and lethal tumor metabolism: implications for breast cancer prevention.
    Sanchez-Alvarez R, Martinez-Outschoorn UE, Lin Z, Lamb R, Hulit J, Howell A, Sotgia F, Rubin E, Lisanti MP.
    Cell Cycle; 2013 Jan 15; 12(2):289-301. PubMed ID: 23257780
    [Abstract] [Full Text] [Related]

  • 16. Cancer metabolism, stemness and tumor recurrence: MCT1 and MCT4 are functional biomarkers of metabolic symbiosis in head and neck cancer.
    Curry JM, Tuluc M, Whitaker-Menezes D, Ames JA, Anantharaman A, Butera A, Leiby B, Cognetti DM, Sotgia F, Lisanti MP, Martinez-Outschoorn UE.
    Cell Cycle; 2013 May 01; 12(9):1371-84. PubMed ID: 23574725
    [Abstract] [Full Text] [Related]

  • 17. Oxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution: A new paradigm for understanding tumor metabolism, the field effect and genomic instability in cancer cells.
    Martinez-Outschoorn UE, Balliet RM, Rivadeneira DB, Chiavarina B, Pavlides S, Wang C, Whitaker-Menezes D, Daumer KM, Lin Z, Witkiewicz AK, Flomenberg N, Howell A, Pestell RG, Knudsen ES, Sotgia F, Lisanti MP.
    Cell Cycle; 2010 Aug 15; 9(16):3256-76. PubMed ID: 20814239
    [Abstract] [Full Text] [Related]

  • 18. Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NFκB activation in the tumor stromal microenvironment.
    Martinez-Outschoorn UE, Trimmer C, Lin Z, Whitaker-Menezes D, Chiavarina B, Zhou J, Wang C, Pavlides S, Martinez-Cantarin MP, Capozza F, Witkiewicz AK, Flomenberg N, Howell A, Pestell RG, Caro J, Lisanti MP, Sotgia F.
    Cell Cycle; 2010 Sep 01; 9(17):3515-33. PubMed ID: 20855962
    [Abstract] [Full Text] [Related]

  • 19. Understanding the "lethal" drivers of tumor-stroma co-evolution: emerging role(s) for hypoxia, oxidative stress and autophagy/mitophagy in the tumor micro-environment.
    Lisanti MP, Martinez-Outschoorn UE, Chiavarina B, Pavlides S, Whitaker-Menezes D, Tsirigos A, Witkiewicz A, Lin Z, Balliet R, Howell A, Sotgia F.
    Cancer Biol Ther; 2010 Sep 15; 10(6):537-42. PubMed ID: 20861671
    [Abstract] [Full Text] [Related]

  • 20. Ketones and lactate "fuel" tumor growth and metastasis: Evidence that epithelial cancer cells use oxidative mitochondrial metabolism.
    Bonuccelli G, Tsirigos A, Whitaker-Menezes D, Pavlides S, Pestell RG, Chiavarina B, Frank PG, Flomenberg N, Howell A, Martinez-Outschoorn UE, Sotgia F, Lisanti MP.
    Cell Cycle; 2010 Sep 01; 9(17):3506-14. PubMed ID: 20818174
    [Abstract] [Full Text] [Related]

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