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224 related items for PubMed ID: 22878643

  • 1. The adenosine A3 receptor agonist Cl-IB-MECA induces cell death through Ca²⁺/ROS-dependent down regulation of ERK and Akt in A172 human glioma cells.
    Kim TH, Kim YK, Woo JS.
    Neurochem Res; 2012 Dec; 37(12):2667-77. PubMed ID: 22878643
    [Abstract] [Full Text] [Related]

  • 2. Effects of synthetic A3 adenosine receptor agonists on cell proliferation and viability are receptor independent at micromolar concentrations.
    Mlejnek P, Dolezel P, Frydrych I.
    J Physiol Biochem; 2013 Sep; 69(3):405-17. PubMed ID: 23184730
    [Abstract] [Full Text] [Related]

  • 3. Thio-Cl-IB-MECA, a novel A₃ adenosine receptor agonist, suppresses angiogenesis by regulating PI3K/AKT/mTOR and ERK signaling in endothelial cells.
    Kim GD, Oh J, Jeong LS, Lee SK.
    Biochem Biophys Res Commun; 2013 Jul 19; 437(1):79-86. PubMed ID: 23791876
    [Abstract] [Full Text] [Related]

  • 4. Cl-IB-MECA inhibits human thyroid cancer cell proliferation independently of A3 adenosine receptor activation.
    Morello S, Petrella A, Festa M, Popolo A, Monaco M, Vuttariello E, Chiappetta G, Parente L, Pinto A.
    Cancer Biol Ther; 2008 Feb 19; 7(2):278-84. PubMed ID: 18059189
    [Abstract] [Full Text] [Related]

  • 5. A novel adenosine analog, thio-Cl-IB-MECA, induces G0/G1 cell cycle arrest and apoptosis in human promyelocytic leukemia HL-60 cells.
    Lee EJ, Min HY, Chung HJ, Park EJ, Shin DH, Jeong LS, Lee SK.
    Biochem Pharmacol; 2005 Sep 15; 70(6):918-24. PubMed ID: 16051194
    [Abstract] [Full Text] [Related]

  • 6. P-glycoprotein mediates resistance to A3 adenosine receptor agonist 2-chloro-N6-(3-iodobenzyl)-adenosine-5'-n-methyluronamide in human leukemia cells.
    Mlejnek P, Dolezel P, Kosztyu P.
    J Cell Physiol; 2012 Feb 15; 227(2):676-85. PubMed ID: 21520073
    [Abstract] [Full Text] [Related]

  • 7. Mitochondrial and caspase pathways are involved in the induction of apoptosis by IB-MECA in ovarian cancer cell lines.
    Abedi H, Aghaei M, Panjehpour M, Hajiahmadi S.
    Tumour Biol; 2014 Nov 15; 35(11):11027-39. PubMed ID: 25095978
    [Abstract] [Full Text] [Related]

  • 8. Suppression of inflammation response by a novel A₃ adenosine receptor agonist thio-Cl-IB-MECA through inhibition of Akt and NF-κB signaling.
    Lee HS, Chung HJ, Lee HW, Jeong LS, Lee SK.
    Immunobiology; 2011 Sep 15; 216(9):997-1003. PubMed ID: 21514967
    [Abstract] [Full Text] [Related]

  • 9. Kaempferol induces cell death through ERK and Akt-dependent down-regulation of XIAP and survivin in human glioma cells.
    Jeong JC, Kim MS, Kim TH, Kim YK.
    Neurochem Res; 2009 May 15; 34(5):991-1001. PubMed ID: 18949556
    [Abstract] [Full Text] [Related]

  • 10. Silibinin induces cell death through reactive oxygen species-dependent downregulation of notch-1/ERK/Akt signaling in human breast cancer cells.
    Kim TH, Woo JS, Kim YK, Kim KH.
    J Pharmacol Exp Ther; 2014 May 15; 349(2):268-78. PubMed ID: 24472723
    [Abstract] [Full Text] [Related]

  • 11. Inhibition of cell proliferation through cell cycle arrest and apoptosis by thio-Cl-IB-MECA, a novel A3 adenosine receptor agonist, in human lung cancer cells.
    Kim SJ, Min HY, Chung HJ, Park EJ, Hong JY, Kang YJ, Shin DH, Jeong LS, Lee SK.
    Cancer Lett; 2008 Jun 18; 264(2):309-15. PubMed ID: 18321638
    [Abstract] [Full Text] [Related]

  • 12. Ciglitazone induces caspase-independent apoptosis through down-regulation of XIAP and survivin in human glioma cells.
    Kang DW, Choi CH, Park JY, Kang SK, Kim YK.
    Neurochem Res; 2008 Mar 18; 33(3):551-61. PubMed ID: 17940898
    [Abstract] [Full Text] [Related]

  • 13. Induction of apoptosis by A3 adenosine receptor agonist N-(3-iodobenzyl)-adenosine-5'-N-methylcarboxamide in human leukaemia cells: a possible involvement of intracellular mechanism.
    Mlejnek P, Dolezel P.
    Acta Physiol (Oxf); 2010 Jun 18; 199(2):171-9. PubMed ID: 20121715
    [Abstract] [Full Text] [Related]

  • 14. Underlying mechanism of quercetin-induced cell death in human glioma cells.
    Kim EJ, Choi CH, Park JY, Kang SK, Kim YK.
    Neurochem Res; 2008 Jun 18; 33(6):971-9. PubMed ID: 18322795
    [Abstract] [Full Text] [Related]

  • 15. Induction of apoptosis in rat cardiocytes by A3 adenosine receptor activation and its suppression by isoproterenol.
    Shneyvays V, Jacobson KA, Li AH, Nawrath H, Zinman T, Isaac A, Shainberg A.
    Exp Cell Res; 2000 May 25; 257(1):111-26. PubMed ID: 10854059
    [Abstract] [Full Text] [Related]

  • 16. p53-Independent induction of Fas and apoptosis in leukemic cells by an adenosine derivative, Cl-IB-MECA.
    Kim SG, Ravi G, Hoffmann C, Jung YJ, Kim M, Chen A, Jacobson KA.
    Biochem Pharmacol; 2002 Mar 01; 63(5):871-80. PubMed ID: 11911839
    [Abstract] [Full Text] [Related]

  • 17. A3 adenosine receptor activation inhibits cell proliferation via phosphatidylinositol 3-kinase/Akt-dependent inhibition of the extracellular signal-regulated kinase 1/2 phosphorylation in A375 human melanoma cells.
    Merighi S, Benini A, Mirandola P, Gessi S, Varani K, Leung E, Maclennan S, Borea PA.
    J Biol Chem; 2005 May 20; 280(20):19516-26. PubMed ID: 15774470
    [Abstract] [Full Text] [Related]

  • 18. Cl-IB-MECA [2-chloro-N6-(3-iodobenzyl)adenosine-5'-N-methylcarboxamide] reduces ischemia/reperfusion injury in mice by activating the A3 adenosine receptor.
    Ge ZD, Peart JN, Kreckler LM, Wan TC, Jacobson MA, Gross GJ, Auchampach JA.
    J Pharmacol Exp Ther; 2006 Dec 20; 319(3):1200-10. PubMed ID: 16985166
    [Abstract] [Full Text] [Related]

  • 19. A3 adenosine receptor agonist IB-MECA reverses chronic cerebral ischemia-induced inhibitory avoidance memory deficit.
    Cheng P, Zhang J, Chu Z, Liu W, Lin H, Wu Y, Zhu J.
    Eur J Pharmacol; 2022 Apr 15; 921():174874. PubMed ID: 35278404
    [Abstract] [Full Text] [Related]

  • 20. Cl-IB-MECA enhances TRAIL-induced apoptosis via the modulation of NF-kappaB signalling pathway in thyroid cancer cells.
    Morello S, Sorrentino R, Porta A, Forte G, Popolo A, Petrella A, Pinto A.
    J Cell Physiol; 2009 Nov 15; 221(2):378-86. PubMed ID: 19562684
    [Abstract] [Full Text] [Related]

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