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Journal Abstract Search

233 related items for PubMed ID: 22880001

  • 1. Rapid detection of an ABT-737-sensitive primed for death state in cells using microplate-based respirometry.
    Clerc P, Carey GB, Mehrabian Z, Wei M, Hwang H, Girnun GD, Chen H, Martin SS, Polster BM.
    PLoS One; 2012; 7(8):e42487. PubMed ID: 22880001
    [Abstract] [Full Text] [Related]

  • 2. Drp1 is dispensable for apoptotic cytochrome c release in primed MCF10A and fibroblast cells but affects Bcl-2 antagonist-induced respiratory changes.
    Clerc P, Ge SX, Hwang H, Waddell J, Roelofs BA, Karbowski M, Sesaki H, Polster BM.
    Br J Pharmacol; 2014 Apr; 171(8):1988-99. PubMed ID: 24206264
    [Abstract] [Full Text] [Related]

  • 3. Granzyme B triggers a prolonged pressure to die in Bcl-2 overexpressing cells, defining a window of opportunity for effective treatment with ABT-737.
    Sutton VR, Sedelies K, Dewson G, Christensen ME, Bird PI, Johnstone RW, Kluck RM, Trapani JA, Waterhouse NJ.
    Cell Death Dis; 2012 Jul 05; 3(7):e344. PubMed ID: 22764103
    [Abstract] [Full Text] [Related]

  • 4. Mcl-1 down-regulation potentiates ABT-737 lethality by cooperatively inducing Bak activation and Bax translocation.
    Chen S, Dai Y, Harada H, Dent P, Grant S.
    Cancer Res; 2007 Jan 15; 67(2):782-91. PubMed ID: 17234790
    [Abstract] [Full Text] [Related]

  • 5. Efficient elimination of cancer cells by deoxyglucose-ABT-263/737 combination therapy.
    Yamaguchi R, Janssen E, Perkins G, Ellisman M, Kitada S, Reed JC.
    PLoS One; 2011 Jan 15; 6(9):e24102. PubMed ID: 21949692
    [Abstract] [Full Text] [Related]

  • 6. Bcl-2, Bcl-x(L), and Bcl-w are not equivalent targets of ABT-737 and navitoclax (ABT-263) in lymphoid and leukemic cells.
    Mérino D, Khaw SL, Glaser SP, Anderson DJ, Belmont LD, Wong C, Yue P, Robati M, Phipson B, Fairlie WD, Lee EF, Campbell KJ, Vandenberg CJ, Cory S, Roberts AW, Ludlam MJ, Huang DC, Bouillet P.
    Blood; 2012 Jun 14; 119(24):5807-16. PubMed ID: 22538851
    [Abstract] [Full Text] [Related]

  • 7. Clitocine induces apoptosis and enhances the lethality of ABT-737 in human colon cancer cells by disrupting the interaction of Mcl-1 and Bak.
    Sun JG, Xiang J, Zeng XL, Li X, Wu P, Fung KP, Liu FY.
    Cancer Lett; 2014 Dec 28; 355(2):253-63. PubMed ID: 25304383
    [Abstract] [Full Text] [Related]

  • 8. Inhibition of phosphatidylinositol 3-kinase/AKT signaling by NVP-BKM120 promotes ABT-737-induced toxicity in a caspase-dependent manner through mitochondrial dysfunction and DNA damage response in established and primary cultured glioblastoma cells.
    Jane EP, Premkumar DR, Morales A, Foster KA, Pollack IF.
    J Pharmacol Exp Ther; 2014 Jul 28; 350(1):22-35. PubMed ID: 24741074
    [Abstract] [Full Text] [Related]

  • 9. The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized.
    van Delft MF, Wei AH, Mason KD, Vandenberg CJ, Chen L, Czabotar PE, Willis SN, Scott CL, Day CL, Cory S, Adams JM, Roberts AW, Huang DC.
    Cancer Cell; 2006 Nov 28; 10(5):389-99. PubMed ID: 17097561
    [Abstract] [Full Text] [Related]

  • 10. Actinomycin D synergistically enhances the efficacy of the BH3 mimetic ABT-737 by downregulating Mcl-1 expression.
    Olberding KE, Wang X, Zhu Y, Pan J, Rai SN, Li C.
    Cancer Biol Ther; 2010 Nov 01; 10(9):918-29. PubMed ID: 20818182
    [Abstract] [Full Text] [Related]

  • 11. Different forms of cell death induced by putative BCL2 inhibitors.
    Vogler M, Weber K, Dinsdale D, Schmitz I, Schulze-Osthoff K, Dyer MJ, Cohen GM.
    Cell Death Differ; 2009 Jul 01; 16(7):1030-9. PubMed ID: 19390557
    [Abstract] [Full Text] [Related]

  • 12. BH3 mimetic ABT-737 potentiates TRAIL-mediated apoptotic signaling by unsequestering Bim and Bak in human pancreatic cancer cells.
    Huang S, Sinicrope FA.
    Cancer Res; 2008 Apr 15; 68(8):2944-51. PubMed ID: 18413764
    [Abstract] [Full Text] [Related]

  • 13. Targeting BCL-2 family proteins to overcome drug resistance in non-small cell lung cancer.
    Wesarg E, Hoffarth S, Wiewrodt R, Kröll M, Biesterfeld S, Huber C, Schuler M.
    Int J Cancer; 2007 Dec 01; 121(11):2387-94. PubMed ID: 17688235
    [Abstract] [Full Text] [Related]

  • 14. ABT-737 synergizes with bortezomib to induce apoptosis, mediated by Bid cleavage, Bax activation, and mitochondrial dysfunction in an Akt-dependent context in malignant human glioma cell lines.
    Premkumar DR, Jane EP, DiDomenico JD, Vukmer NA, Agostino NR, Pollack IF.
    J Pharmacol Exp Ther; 2012 Jun 01; 341(3):859-72. PubMed ID: 22393246
    [Abstract] [Full Text] [Related]

  • 15. Co-administration of ABT-737 and SAHA induces apoptosis, mediated by Noxa upregulation, Bax activation and mitochondrial dysfunction in PTEN-intact malignant human glioma cell lines.
    Foster KA, Jane EP, Premkumar DR, Morales A, Pollack IF.
    J Neurooncol; 2014 Dec 01; 120(3):459-72. PubMed ID: 25139025
    [Abstract] [Full Text] [Related]

  • 16. ABT-737 induces apoptosis in mantle cell lymphoma cells with a Bcl-2high/Mcl-1low profile and synergizes with other antineoplastic agents.
    Touzeau C, Dousset C, Bodet L, Gomez-Bougie P, Bonnaud S, Moreau A, Moreau P, Pellat-Deceunynck C, Amiot M, Le Gouill S.
    Clin Cancer Res; 2011 Sep 15; 17(18):5973-81. PubMed ID: 21821698
    [Abstract] [Full Text] [Related]

  • 17. Use of human cancer cell lines mitochondria to explore the mechanisms of BH3 peptides and ABT-737-induced mitochondrial membrane permeabilization.
    Buron N, Porceddu M, Brabant M, Desgué D, Racoeur C, Lassalle M, Péchoux C, Rustin P, Jacotot E, Borgne-Sanchez A.
    PLoS One; 2010 Mar 31; 5(3):e9924. PubMed ID: 20360986
    [Abstract] [Full Text] [Related]

  • 18. Mechanism of synergy of N-(4-hydroxyphenyl)retinamide and ABT-737 in acute lymphoblastic leukemia cell lines: Mcl-1 inactivation.
    Kang MH, Wan Z, Kang YH, Sposto R, Reynolds CP.
    J Natl Cancer Inst; 2008 Apr 16; 100(8):580-95. PubMed ID: 18398104
    [Abstract] [Full Text] [Related]

  • 19. Prosurvival Bcl-2 family members affect autophagy only indirectly, by inhibiting Bax and Bak.
    Lindqvist LM, Heinlein M, Huang DC, Vaux DL.
    Proc Natl Acad Sci U S A; 2014 Jun 10; 111(23):8512-7. PubMed ID: 24912196
    [Abstract] [Full Text] [Related]

  • 20. Activity of vincristine, L-ASP, and dexamethasone against acute lymphoblastic leukemia is enhanced by the BH3-mimetic ABT-737 in vitro and in vivo.
    Kang MH, Kang YH, Szymanska B, Wilczynska-Kalak U, Sheard MA, Harned TM, Lock RB, Reynolds CP.
    Blood; 2007 Sep 15; 110(6):2057-66. PubMed ID: 17536015
    [Abstract] [Full Text] [Related]

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