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Journal Abstract Search

131 related items for PubMed ID: 22882079

  • 21. Discovery of further pyrrolidine trans-lactams as inhibitors of human neutrophil elastase (HNE) with potential as development candidates and the crystal structure of HNE complexed with an inhibitor (GW475151).
    Macdonald SJ, Dowle MD, Harrison LA, Clarke GD, Inglis GG, Johnson MR, Shah P, Smith RA, Amour A, Fleetwood G, Humphreys DC, Molloy CR, Dixon M, Godward RE, Wonacott AJ, Singh OM, Hodgson ST, Hardy GW.
    J Med Chem; 2002 Aug 29; 45(18):3878-90. PubMed ID: 12190311
    [Abstract] [Full Text] [Related]

  • 22. N-Acyl and N-sulfonyloxazolidine-2,4-diones are pseudo-irreversible inhibitors of serine proteases.
    Santana AB, Lucas SD, Gonçalves LM, Correia HF, Cardote TA, Guedes RC, Iley J, Moreira R.
    Bioorg Med Chem Lett; 2012 Jun 15; 22(12):3993-7. PubMed ID: 22595175
    [Abstract] [Full Text] [Related]

  • 23. Novel neutrophil elastase inhibitors as a treatment for neutrophil-predominant inflammatory lung diseases.
    Ohbayashi H.
    IDrugs; 2002 Sep 15; 5(9):910-23. PubMed ID: 12800053
    [Abstract] [Full Text] [Related]

  • 24. Design and synthesis of peptide-based carboxylic acid-containing transition-state inhibitors of human neutrophil elastase.
    Sato F, Inoue Y, Omodani T, Imano K, Okazaki H, Takemura T, Komiya M.
    Bioorg Med Chem Lett; 2002 Feb 25; 12(4):551-5. PubMed ID: 11844670
    [Abstract] [Full Text] [Related]

  • 25. Design, synthesis and evaluation of N-benzoylindazole derivatives and analogues as inhibitors of human neutrophil elastase.
    Crocetti L, Giovannoni MP, Schepetkin IA, Quinn MT, Khlebnikov AI, Cilibrizzi A, Piaz VD, Graziano A, Vergelli C.
    Bioorg Med Chem; 2011 Aug 01; 19(15):4460-72. PubMed ID: 21741848
    [Abstract] [Full Text] [Related]

  • 26. Clickable 4-Oxo-β-lactam-Based Selective Probing for Human Neutrophil Elastase Related Proteomes.
    Ruivo EF, Gonçalves LM, Carvalho LA, Guedes RC, Hofbauer S, Brito JA, Archer M, Moreira R, Lucas SD.
    ChemMedChem; 2016 Sep 20; 11(18):2037-42. PubMed ID: 27465595
    [Abstract] [Full Text] [Related]

  • 27. Ahp-Cyclodepsipeptides as tunable inhibitors of human neutrophil elastase and kallikrein 7: Total synthesis of tutuilamide A, serine protease selectivity profile and comparison with lyngbyastatin 7.
    Chen QY, Luo D, Seabra GM, Luesch H.
    Bioorg Med Chem; 2020 Dec 01; 28(23):115756. PubMed ID: 33002682
    [Abstract] [Full Text] [Related]

  • 28. Structure activity relationship studies of cinnamic acid derivatives as inhibitors of human neutrophil elastase revealed by ligand docking calculations.
    Siedle B, Murillo R, Hucke O, Labahn A, Merfort I.
    Pharmazie; 2003 May 01; 58(5):337-9. PubMed ID: 12779051
    [Abstract] [Full Text] [Related]

  • 29. New peptolides from the cyanobacterium Nostoc insulare as selective and potent inhibitors of human leukocyte elastase.
    Mehner C, Müller D, Kehraus S, Hautmann S, Gütschow M, König GM.
    Chembiochem; 2008 Nov 03; 9(16):2692-703. PubMed ID: 18924217
    [Abstract] [Full Text] [Related]

  • 30. Natural compounds as inhibitors of human neutrophil elastase.
    Siedle B, Hrenn A, Merfort I.
    Planta Med; 2007 May 03; 73(5):401-20. PubMed ID: 17447201
    [Abstract] [Full Text] [Related]

  • 31. Intratracheally-instilled antileukoprotease and alpha 1-proteinase inhibitor: effect on human neutrophil elastase-induced experimental emphysema and pulmonary localization.
    Rudolphus A, Kramps JA, Mauve I, Dijkman JH.
    Histochem J; 1994 Oct 03; 26(10):817-24. PubMed ID: 7883591
    [Abstract] [Full Text] [Related]

  • 32. Chemical constituents from the leaves of Ilex paraguariensis inhibit human neutrophil elastase.
    Xu GH, Kim YH, Choo SJ, Ryoo IJ, Yoo JK, Ahn JS, Yoo ID.
    Arch Pharm Res; 2009 Sep 03; 32(9):1215-20. PubMed ID: 19784576
    [Abstract] [Full Text] [Related]

  • 33. ONO-6818 Cortech/Ono.
    Trifilieff A.
    Curr Opin Investig Drugs; 2002 Aug 03; 3(8):1161-4. PubMed ID: 12211408
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  • 35. 1H-pyrrolo[2,3-b]pyridine: A new scaffold for human neutrophil elastase (HNE) inhibitors.
    Crocetti L, Giovannoni MP, Schepetkin IA, Quinn MT, Khlebnikov AI, Cantini N, Guerrini G, Iacovone A, Teodori E, Vergelli C.
    Bioorg Med Chem; 2018 Nov 15; 26(21):5583-5595. PubMed ID: 30385225
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