These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


PUBMED FOR HANDHELDS

Journal Abstract Search


203 related items for PubMed ID: 22889611

  • 1. The trypanothione system and its implications in the therapy of trypanosomatid diseases.
    Flohé L.
    Int J Med Microbiol; 2012 Oct; 302(4-5):216-20. PubMed ID: 22889611
    [Abstract] [Full Text] [Related]

  • 2. Gamma-glutamylcysteine synthetase and tryparedoxin 1 exert high control on the antioxidant system in Trypanosoma cruzi contributing to drug resistance and infectivity.
    González-Chávez Z, Vázquez C, Mejia-Tlachi M, Márquez-Dueñas C, Manning-Cela R, Encalada R, Rodríguez-Enríquez S, Michels PAM, Moreno-Sánchez R, Saavedra E.
    Redox Biol; 2019 Sep; 26():101231. PubMed ID: 31203195
    [Abstract] [Full Text] [Related]

  • 3. Targeting trypanothione metabolism in trypanosomatid human parasites.
    Olin-Sandoval V, Moreno-Sánchez R, Saavedra E.
    Curr Drug Targets; 2010 Dec; 11(12):1614-30. PubMed ID: 20735352
    [Abstract] [Full Text] [Related]

  • 4. The trypanothione system and the opportunities it offers to create drugs for the neglected kinetoplast diseases.
    Flohé L.
    Biotechnol Adv; 2012 Dec; 30(1):294-301. PubMed ID: 21620942
    [Abstract] [Full Text] [Related]

  • 5. Targeting Trypanothione Metabolism in Trypanosomatids.
    González-Montero MC, Andrés-Rodríguez J, García-Fernández N, Pérez-Pertejo Y, Reguera RM, Balaña-Fouce R, García-Estrada C.
    Molecules; 2024 May 09; 29(10):. PubMed ID: 38792079
    [Abstract] [Full Text] [Related]

  • 6. Enzymes of the trypanothione metabolism as targets for antitrypanosomal drug development.
    Schmidt A, Krauth-Siegel RL.
    Curr Top Med Chem; 2002 Nov 09; 2(11):1239-59. PubMed ID: 12171583
    [Abstract] [Full Text] [Related]

  • 7. The parasite-specific trypanothione metabolism of trypanosoma and leishmania.
    Krauth-Siegel RL, Meiering SK, Schmidt H.
    Biol Chem; 2003 Apr 09; 384(4):539-49. PubMed ID: 12751784
    [Abstract] [Full Text] [Related]

  • 8. Structural insights into the enzymes of the trypanothione pathway: targets for antileishmaniasis drugs.
    Colotti G, Baiocco P, Fiorillo A, Boffi A, Poser E, Chiaro FD, Ilari A.
    Future Med Chem; 2013 Oct 09; 5(15):1861-75. PubMed ID: 24144416
    [Abstract] [Full Text] [Related]

  • 9. The Achilles' heel of trypanosomatids: trypanothione-mediated hydroperoxide metabolism.
    Flohé L.
    Biofactors; 1998 Oct 09; 8(1-2):87-91. PubMed ID: 9699014
    [No Abstract] [Full Text] [Related]

  • 10. Recent Advancement in the Search of Innovative Antiprotozoal Agents Targeting Trypanothione Metabolism.
    Saccoliti F, Di Santo R, Costi R.
    ChemMedChem; 2020 Dec 15; 15(24):2420-2435. PubMed ID: 32805075
    [Abstract] [Full Text] [Related]

  • 11. Thiol-based redox metabolism of protozoan parasites.
    Müller S, Liebau E, Walter RD, Krauth-Siegel RL.
    Trends Parasitol; 2003 Jul 15; 19(7):320-8. PubMed ID: 12855383
    [Abstract] [Full Text] [Related]

  • 12. Glutathione and trypanothione in parasitic hydroperoxide metabolism.
    Flohé L, Hecht HJ, Steinert P.
    Free Radic Biol Med; 1999 Nov 15; 27(9-10):966-84. PubMed ID: 10569629
    [Abstract] [Full Text] [Related]

  • 13. Preparative enzymatic synthesis of trypanothione and trypanothione analogues.
    Comini MA, Dirdjaja N, Kaschel M, Krauth-Siegel RL.
    Int J Parasitol; 2009 Aug 15; 39(10):1059-62. PubMed ID: 19477177
    [Abstract] [Full Text] [Related]

  • 14. Peroxidases of trypanosomatids.
    Castro H, Tomás AM.
    Antioxid Redox Signal; 2008 Sep 15; 10(9):1593-606. PubMed ID: 18498224
    [Abstract] [Full Text] [Related]

  • 15. Drug target validation of the trypanothione pathway enzymes through metabolic modelling.
    Olin-Sandoval V, González-Chávez Z, Berzunza-Cruz M, Martínez I, Jasso-Chávez R, Becker I, Espinoza B, Moreno-Sánchez R, Saavedra E.
    FEBS J; 2012 May 15; 279(10):1811-33. PubMed ID: 22394478
    [Abstract] [Full Text] [Related]

  • 16. Trypanothione biosynthesis in Leishmania major.
    Oza SL, Shaw MP, Wyllie S, Fairlamb AH.
    Mol Biochem Parasitol; 2005 Jan 15; 139(1):107-16. PubMed ID: 15610825
    [Abstract] [Full Text] [Related]

  • 17. Cynaropicrin targets the trypanothione redox system in Trypanosoma brucei.
    Zimmermann S, Oufir M, Leroux A, Krauth-Siegel RL, Becker K, Kaiser M, Brun R, Hamburger M, Adams M.
    Bioorg Med Chem; 2013 Nov 15; 21(22):7202-9. PubMed ID: 24080104
    [Abstract] [Full Text] [Related]

  • 18. Thiol redox biology of trypanosomatids and potential targets for chemotherapy.
    Leroux AE, Krauth-Siegel RL.
    Mol Biochem Parasitol; 2016 Nov 15; 206(1-2):67-74. PubMed ID: 26592324
    [Abstract] [Full Text] [Related]

  • 19. Phenotypic analysis of trypanothione synthetase knockdown in the African trypanosome.
    Ariyanayagam MR, Oza SL, Guther ML, Fairlamb AH.
    Biochem J; 2005 Oct 15; 391(Pt 2):425-32. PubMed ID: 16008527
    [Abstract] [Full Text] [Related]

  • 20. Insights into the redox biology of Trypanosoma cruzi: Trypanothione metabolism and oxidant detoxification.
    Irigoín F, Cibils L, Comini MA, Wilkinson SR, Flohé L, Radi R.
    Free Radic Biol Med; 2008 Sep 15; 45(6):733-42. PubMed ID: 18588970
    [Abstract] [Full Text] [Related]


    Page: [Next] [New Search]
    of 11.