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Journal Abstract Search

360 related items for PubMed ID: 22914623

  • 1. Targeted disruption of the BCL9/β-catenin complex inhibits oncogenic Wnt signaling.
    Takada K, Zhu D, Bird GH, Sukhdeo K, Zhao JJ, Mani M, Lemieux M, Carrasco DE, Ryan J, Horst D, Fulciniti M, Munshi NC, Xu W, Kung AL, Shivdasani RA, Walensky LD, Carrasco DR.
    Sci Transl Med; 2012 Aug 22; 4(148):148ra117. PubMed ID: 22914623
    [Abstract] [Full Text] [Related]

  • 2. SOX7 Suppresses Wnt Signaling by Disrupting β-Catenin/BCL9 Interaction.
    Fan R, He H, Yao W, Zhu Y, Zhou X, Gui M, Lu J, Xi H, Deng Z, Fan M.
    DNA Cell Biol; 2018 Feb 22; 37(2):126-132. PubMed ID: 29271667
    [Abstract] [Full Text] [Related]

  • 3. LATS2 suppresses oncogenic Wnt signaling by disrupting β-catenin/BCL9 interaction.
    Li J, Chen X, Ding X, Cheng Y, Zhao B, Lai ZC, Al Hezaimi K, Hakem R, Guan KL, Wang CY.
    Cell Rep; 2013 Dec 26; 5(6):1650-63. PubMed ID: 24360964
    [Abstract] [Full Text] [Related]

  • 4. LncRNA NCK1-AS1 exerts oncogenic property in gastric cancer by targeting the miR-22-3p/BCL9 axis to activate the Wnt/β-catenin signaling.
    Guan B, Ma J, Yang Z, Yu F, Yao J.
    Environ Toxicol; 2021 Aug 26; 36(8):1640-1653. PubMed ID: 33974352
    [Abstract] [Full Text] [Related]

  • 5. Hypoxia activates Wnt/β-catenin signaling by regulating the expression of BCL9 in human hepatocellular carcinoma.
    Xu W, Zhou W, Cheng M, Wang J, Liu Z, He S, Luo X, Huang W, Chen T, Yan W, Xiao J.
    Sci Rep; 2017 Jan 11; 7():40446. PubMed ID: 28074862
    [Abstract] [Full Text] [Related]

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  • 7. miR-1301 inhibits hepatocellular carcinoma cell migration, invasion, and angiogenesis by decreasing Wnt/β-catenin signaling through targeting BCL9.
    Yang C, Xu Y, Cheng F, Hu Y, Yang S, Rao J, Wang X.
    Cell Death Dis; 2017 Aug 17; 8(8):e2999. PubMed ID: 28817119
    [Abstract] [Full Text] [Related]

  • 8. A novel β-catenin/BCL9 complex inhibitor blocks oncogenic Wnt signaling and disrupts cholesterol homeostasis in colorectal cancer.
    Tanton H, Sewastianik T, Seo HS, Remillard D, Pierre RS, Bala P, Aitymbayev D, Dennis P, Adler K, Geffken E, Yeoh Z, Vangos N, Garbicz F, Scott D, Sethi N, Bradner J, Dhe-Paganon S, Carrasco RD.
    Sci Adv; 2022 Apr 29; 8(17):eabm3108. PubMed ID: 35486727
    [Abstract] [Full Text] [Related]

  • 9. The function of BCL9 in Wnt/beta-catenin signaling and colorectal cancer cells.
    de la Roche M, Worm J, Bienz M.
    BMC Cancer; 2008 Jul 15; 8():199. PubMed ID: 18627596
    [Abstract] [Full Text] [Related]

  • 10. The interactions of Bcl9/Bcl9L with β-catenin and Pygopus promote breast cancer growth, invasion, and metastasis.
    Vafaizadeh V, Buechel D, Rubinstein N, Kalathur RKR, Bazzani L, Saxena M, Valenta T, Hausmann G, Cantù C, Basler K, Christofori G.
    Oncogene; 2021 Oct 15; 40(43):6195-6209. PubMed ID: 34545187
    [Abstract] [Full Text] [Related]

  • 11. Cell-type-specific function of BCL9 involves a transcriptional activation domain that synergizes with beta-catenin.
    Sustmann C, Flach H, Ebert H, Eastman Q, Grosschedl R.
    Mol Cell Biol; 2008 May 15; 28(10):3526-37. PubMed ID: 18347063
    [Abstract] [Full Text] [Related]

  • 12. Fusion of the BCL9 HD2 domain to E1A increases the cytopathic effect of an oncolytic adenovirus that targets colon cancer cells.
    Fuerer C, Homicsko K, Lukashev AN, Pittet AL, Iggo RD.
    BMC Cancer; 2006 Oct 04; 6():236. PubMed ID: 17020613
    [Abstract] [Full Text] [Related]

  • 13. Wnt status-dependent oncogenic role of BCL9 and BCL9L in hepatocellular carcinoma.
    Huge N, Sandbothe M, Schröder AK, Stalke A, Eilers M, Schäffer V, Schlegelberger B, Illig T, Vajen B, Skawran B.
    Hepatol Int; 2020 May 04; 14(3):373-384. PubMed ID: 31440992
    [Abstract] [Full Text] [Related]

  • 14. Analysis of the interaction of BCL9 with beta-catenin and development of fluorescence polarization and surface plasmon resonance binding assays for this interaction.
    Kawamoto SA, Thompson AD, Coleska A, Nikolovska-Coleska Z, Yi H, Wang S.
    Biochemistry; 2009 Oct 13; 48(40):9534-41. PubMed ID: 19715304
    [Abstract] [Full Text] [Related]

  • 15. Wnt/β-catenin signaling regulates Yes-associated protein (YAP) gene expression in colorectal carcinoma cells.
    Konsavage WM, Kyler SL, Rennoll SA, Jin G, Yochum GS.
    J Biol Chem; 2012 Apr 06; 287(15):11730-9. PubMed ID: 22337891
    [Abstract] [Full Text] [Related]

  • 16. Loss of BCL9/9l suppresses Wnt driven tumourigenesis in models that recapitulate human cancer.
    Gay DM, Ridgway RA, Müller M, Hodder MC, Hedley A, Clark W, Leach JD, Jackstadt R, Nixon C, Huels DJ, Campbell AD, Bird TG, Sansom OJ.
    Nat Commun; 2019 Feb 13; 10(1):723. PubMed ID: 30760720
    [Abstract] [Full Text] [Related]

  • 17. Positive feedback regulation between phospholipase D and Wnt signaling promotes Wnt-driven anchorage-independent growth of colorectal cancer cells.
    Kang DW, Min do S.
    PLoS One; 2010 Aug 12; 5(8):e12109. PubMed ID: 20711340
    [Abstract] [Full Text] [Related]

  • 18. BCL9 promotes epithelial mesenchymal transition and invasion in cisplatin resistant NSCLC cells via β-catenin pathway.
    Zhang Y, Zhang Q, Chen H, Wang C.
    Life Sci; 2018 Sep 01; 208():284-294. PubMed ID: 30009824
    [Abstract] [Full Text] [Related]

  • 19. Role of a BCL9-related beta-catenin-binding protein, B9L, in tumorigenesis induced by aberrant activation of Wnt signaling.
    Adachi S, Jigami T, Yasui T, Nakano T, Ohwada S, Omori Y, Sugano S, Ohkawara B, Shibuya H, Nakamura T, Akiyama T.
    Cancer Res; 2004 Dec 01; 64(23):8496-501. PubMed ID: 15574752
    [Abstract] [Full Text] [Related]

  • 20. Inhibition of β-catenin/B cell lymphoma 9 protein-protein interaction using α-helix-mimicking sulfono-γ-AApeptide inhibitors.
    Sang P, Zhang M, Shi Y, Li C, Abdulkadir S, Li Q, Ji H, Cai J.
    Proc Natl Acad Sci U S A; 2019 May 28; 116(22):10757-10762. PubMed ID: 31088961
    [Abstract] [Full Text] [Related]

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