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Journal Abstract Search

104 related items for PubMed ID: 2291561

  • 1. The development of hydroxypyridin-4-ones as orally active iron chelators.
    Hider RC, Singh S, Porter JB, Huehns ER.
    Ann N Y Acad Sci; 1990; 612():327-38. PubMed ID: 2291561
    [No Abstract] [Full Text] [Related]

  • 2. The design of orally active iron chelators.
    Hider RC, Zhou T.
    Ann N Y Acad Sci; 2005; 1054():141-54. PubMed ID: 16339660
    [Abstract] [Full Text] [Related]

  • 3. Influence of lipophilicity on the bioavailability and disposition of orally active 3-hydroxypyridin-4-one metal chelators.
    Yokel RA, Fredenburg AM, Meurer KA, Skinner TL.
    Drug Metab Dispos; 1995 Oct; 23(10):1178-80. PubMed ID: 8654208
    [No Abstract] [Full Text] [Related]

  • 4. Synthesis, physicochemical properties and biological evaluation of aromatic ester prodrugs of 1-(2'-hydroxyethyl)-2-ethyl-3-hydroxypyridin-4-one (CP102): orally active iron chelators with clinical potential.
    Liu ZD, Liu DY, Lu SL, Hider RC.
    J Pharm Pharmacol; 1999 May; 51(5):555-64. PubMed ID: 10411215
    [Abstract] [Full Text] [Related]

  • 5. Synthesis, physicochemical properties, and biological evaluation of N-substituted 2-alkyl-3-hydroxy-4(1H)-pyridinones: orally active iron chelators with clinical potential.
    Dobbin PS, Hider RC, Hall AD, Taylor PD, Sarpong P, Porter JB, Xiao G, van der Helm D.
    J Med Chem; 1993 Aug 20; 36(17):2448-58. PubMed ID: 8355246
    [Abstract] [Full Text] [Related]

  • 6. Synthesis of 2-amido-3-hydroxypyridin-4(1H)-ones: novel iron chelators with enhanced pFe3+ values.
    Liu ZD, Piyamongkol S, Liu DY, Khodr HH, Lu SL, Hider RC.
    Bioorg Med Chem; 2001 Mar 20; 9(3):563-73. PubMed ID: 11310590
    [Abstract] [Full Text] [Related]

  • 7. Design, synthesis and evaluation of N-basic substituted 3-hydroxypyridin-4-ones: orally active iron chelators with lysosomotrophic potential.
    Liu ZD, Khodr HH, Lu SL, Hider RC.
    J Pharm Pharmacol; 2000 Mar 20; 52(3):263-72. PubMed ID: 10757413
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  • 13. Basic 3-hydroxypyridin-4-ones: potential antimalarial agents.
    Dehkordi LS, Liu ZD, Hider RC.
    Eur J Med Chem; 2008 May 20; 43(5):1035-47. PubMed ID: 17869385
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  • 14. Protoporphyria induced by the orally active iron chelator 1,2-diethyl-3-hydroxypyridin-4-one in C57BL/10ScSn mice.
    Smith AG, Clothier B, Francis JE, Gibbs AH, De Matteis F, Hider RC.
    Blood; 1997 Feb 01; 89(3):1045-51. PubMed ID: 9028337
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  • 15. Influence of iron chelators, 1,2-dialkyl-3-hydroxypyridin-4-ones, on the lipid peroxidation and glutathione level in the liver of mice.
    Eybl V, Caisová D, Koutenský J, Kontoghiorghes GJ.
    Arch Toxicol Suppl; 1991 Feb 01; 14():185-7. PubMed ID: 1805729
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  • 16. The design and properties of 3-hydroxypyridin-4-one iron chelators with high pFe(3+) values.
    Liu ZD, Piyamongkol S, Hider RC.
    Transfus Sci; 2000 Dec 01; 23(3):269-70. PubMed ID: 11099914
    [No Abstract] [Full Text] [Related]

  • 17. Iron mobilization from hepatocyte monolayer cultures by chelators: the importance of membrane permeability and the iron-binding constant.
    Porter JB, Gyparaki M, Burke LC, Huehns ER, Sarpong P, Saez V, Hider RC.
    Blood; 1988 Nov 01; 72(5):1497-503. PubMed ID: 3179437
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  • 18. Relative oral efficacy and acute toxicity of hydroxypyridin-4-one iron chelators in mice.
    Porter JB, Morgan J, Hoyes KP, Burke LC, Huehns ER, Hider RC.
    Blood; 1990 Dec 01; 76(11):2389-96. PubMed ID: 2257308
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