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Journal Abstract Search

588 related items for PubMed ID: 22921586

  • 1. The mycobacterial cord factor adjuvant analogue trehalose-6,6'-dibehenate (TDB) activates the Nlrp3 inflammasome.
    Schweneker K, Gorka O, Schweneker M, Poeck H, Tschopp J, Peschel C, Ruland J, Gross O.
    Immunobiology; 2013 Apr; 218(4):664-73. PubMed ID: 22921586
    [Abstract] [Full Text] [Related]

  • 2. Contribution of MINCLE-SYK Signaling to Activation of Primary Human APCs by Mycobacterial Cord Factor and the Novel Adjuvant TDB.
    Ostrop J, Jozefowski K, Zimmermann S, Hofmann K, Strasser E, Lepenies B, Lang R.
    J Immunol; 2015 Sep 01; 195(5):2417-28. PubMed ID: 26202982
    [Abstract] [Full Text] [Related]

  • 3. Differential control of Mincle-dependent cord factor recognition and macrophage responses by the transcription factors C/EBPβ and HIF1α.
    Schoenen H, Huber A, Sonda N, Zimmermann S, Jantsch J, Lepenies B, Bronte V, Lang R.
    J Immunol; 2014 Oct 01; 193(7):3664-75. PubMed ID: 25156364
    [Abstract] [Full Text] [Related]

  • 4. Tripartite-motif protein 30 negatively regulates NLRP3 inflammasome activation by modulating reactive oxygen species production.
    Hu Y, Mao K, Zeng Y, Chen S, Tao Z, Yang C, Sun S, Wu X, Meng G, Sun B.
    J Immunol; 2010 Dec 15; 185(12):7699-705. PubMed ID: 21048113
    [Abstract] [Full Text] [Related]

  • 5. An ITAM-Syk-CARD9 signalling axis triggers contact hypersensitivity by stimulating IL-1 production in dendritic cells.
    Yasukawa S, Miyazaki Y, Yoshii C, Nakaya M, Ozaki N, Toda S, Kuroda E, Ishibashi K, Yasuda T, Natsuaki Y, Mi-ichi F, Iizasa E, Nakahara T, Yamazaki M, Kabashima K, Iwakura Y, Takai T, Saito T, Kurosaki T, Malissen B, Ohno N, Furue M, Yoshida H, Hara H.
    Nat Commun; 2014 May 07; 5():3755. PubMed ID: 24806599
    [Abstract] [Full Text] [Related]

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  • 7. Mycobacterium abscessus activates the NLRP3 inflammasome via Dectin-1-Syk and p62/SQSTM1.
    Lee HM, Yuk JM, Kim KH, Jang J, Kang G, Park JB, Son JW, Jo EK.
    Immunol Cell Biol; 2012 Jul 07; 90(6):601-10. PubMed ID: 21876553
    [Abstract] [Full Text] [Related]

  • 8. Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence.
    Gross O, Poeck H, Bscheider M, Dostert C, Hannesschläger N, Endres S, Hartmann G, Tardivel A, Schweighoffer E, Tybulewicz V, Mocsai A, Tschopp J, Ruland J.
    Nature; 2009 May 21; 459(7245):433-6. PubMed ID: 19339971
    [Abstract] [Full Text] [Related]

  • 9. Malassezia yeasts activate the NLRP3 inflammasome in antigen-presenting cells via Syk-kinase signalling.
    Kistowska M, Fenini G, Jankovic D, Feldmeyer L, Kerl K, Bosshard P, Contassot E, French LE.
    Exp Dermatol; 2014 Dec 21; 23(12):884-9. PubMed ID: 25267545
    [Abstract] [Full Text] [Related]

  • 10. Internalized Cryptococcus neoformans Activates the Canonical Caspase-1 and the Noncanonical Caspase-8 Inflammasomes.
    Chen M, Xing Y, Lu A, Fang W, Sun B, Chen C, Liao W, Meng G.
    J Immunol; 2015 Nov 15; 195(10):4962-72. PubMed ID: 26466953
    [Abstract] [Full Text] [Related]

  • 11. Mechanisms that lead to the regulation of NLRP3 inflammasome expression and activation in human dental pulp fibroblasts.
    Zhang A, Wang P, Ma X, Yin X, Li J, Wang H, Jiang W, Jia Q, Ni L.
    Mol Immunol; 2015 Aug 15; 66(2):253-62. PubMed ID: 25863775
    [Abstract] [Full Text] [Related]

  • 12. The Mincle-activating adjuvant TDB induces MyD88-dependent Th1 and Th17 responses through IL-1R signaling.
    Desel C, Werninghaus K, Ritter M, Jozefowski K, Wenzel J, Russkamp N, Schleicher U, Christensen D, Wirtz S, Kirschning C, Agger EM, Prazeres da Costa C, Lang R.
    PLoS One; 2013 Aug 15; 8(1):e53531. PubMed ID: 23308247
    [Abstract] [Full Text] [Related]

  • 13. C-type lectin receptor dectin-3 mediates trehalose 6,6'-dimycolate (TDM)-induced Mincle expression through CARD9/Bcl10/MALT1-dependent nuclear factor (NF)-κB activation.
    Zhao XQ, Zhu LL, Chang Q, Jiang C, You Y, Luo T, Jia XM, Lin X.
    J Biol Chem; 2014 Oct 24; 289(43):30052-62. PubMed ID: 25202022
    [Abstract] [Full Text] [Related]

  • 14. Cutting edge: Mincle is essential for recognition and adjuvanticity of the mycobacterial cord factor and its synthetic analog trehalose-dibehenate.
    Schoenen H, Bodendorfer B, Hitchens K, Manzanero S, Werninghaus K, Nimmerjahn F, Agger EM, Stenger S, Andersen P, Ruland J, Brown GD, Wells C, Lang R.
    J Immunol; 2010 Mar 15; 184(6):2756-60. PubMed ID: 20164423
    [Abstract] [Full Text] [Related]

  • 15. CEACAM1 negatively regulates IL-1β production in LPS activated neutrophils by recruiting SHP-1 to a SYK-TLR4-CEACAM1 complex.
    Lu R, Pan H, Shively JE.
    PLoS Pathog; 2012 Mar 15; 8(4):e1002597. PubMed ID: 22496641
    [Abstract] [Full Text] [Related]

  • 16. Reactive oxygen species activated NLRP3 inflammasomes prime environment-induced murine dry eye.
    Zheng Q, Ren Y, Reinach PS, She Y, Xiao B, Hua S, Qu J, Chen W.
    Exp Eye Res; 2014 Aug 15; 125():1-8. PubMed ID: 24836981
    [Abstract] [Full Text] [Related]

  • 17. Trehalose diester glycolipids are superior to the monoesters in binding to Mincle, activation of macrophages in vitro and adjuvant activity in vivo.
    Huber A, Kallerup RS, Korsholm KS, Franzyk H, Lepenies B, Christensen D, Foged C, Lang R.
    Innate Immun; 2016 Aug 15; 22(6):405-18. PubMed ID: 27252171
    [Abstract] [Full Text] [Related]

  • 18. Serum amyloid A induces NLRP-3-mediated IL-1β secretion in neutrophils.
    Migita K, Izumi Y, Jiuchi Y, Kozuru H, Kawahara C, Nakamura M, Nakamura T, Agematsu K, Masumoto J, Yasunami M, Kawakami A, Eguchi K.
    PLoS One; 2014 Aug 15; 9(5):e96703. PubMed ID: 24846290
    [Abstract] [Full Text] [Related]

  • 19. Dectin-2 is a primary receptor for NLRP3 inflammasome activation in dendritic cell response to Histoplasma capsulatum.
    Chang TH, Huang JH, Lin HC, Chen WY, Lee YH, Hsu LC, Netea MG, Ting JP, Wu-Hsieh BA.
    PLoS Pathog; 2017 Jul 15; 13(7):e1006485. PubMed ID: 28671985
    [Abstract] [Full Text] [Related]

  • 20. Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases.
    Shio MT, Eisenbarth SC, Savaria M, Vinet AF, Bellemare MJ, Harder KW, Sutterwala FS, Bohle DS, Descoteaux A, Flavell RA, Olivier M.
    PLoS Pathog; 2009 Aug 15; 5(8):e1000559. PubMed ID: 19696895
    [Abstract] [Full Text] [Related]

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