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330 related items for PubMed ID: 22922338

  • 1. Capsazepine, a TRPV1 antagonist, sensitizes colorectal cancer cells to apoptosis by TRAIL through ROS-JNK-CHOP-mediated upregulation of death receptors.
    Sung B, Prasad S, Ravindran J, Yadav VR, Aggarwal BB.
    Free Radic Biol Med; 2012 Nov 15; 53(10):1977-87. PubMed ID: 22922338
    [Abstract] [Full Text] [Related]

  • 2. Quercetin enhances apoptotic effect of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in ovarian cancer cells through reactive oxygen species (ROS) mediated CCAAT enhancer-binding protein homologous protein (CHOP)-death receptor 5 pathway.
    Yi L, Zongyuan Y, Cheng G, Lingyun Z, Guilian Y, Wei G.
    Cancer Sci; 2014 May 15; 105(5):520-7. PubMed ID: 24612139
    [Abstract] [Full Text] [Related]

  • 3. Azadirone, a limonoid tetranortriterpene, induces death receptors and sensitizes human cancer cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) through a p53 protein-independent mechanism: evidence for the role of the ROS-ERK-CHOP-death receptor pathway.
    Gupta SC, Francis SK, Nair MS, Mo YY, Aggarwal BB.
    J Biol Chem; 2013 Nov 08; 288(45):32343-32356. PubMed ID: 24078627
    [Abstract] [Full Text] [Related]

  • 4. Gossypol induces death receptor-5 through activation of the ROS-ERK-CHOP pathway and sensitizes colon cancer cells to TRAIL.
    Sung B, Ravindran J, Prasad S, Pandey MK, Aggarwal BB.
    J Biol Chem; 2010 Nov 12; 285(46):35418-27. PubMed ID: 20837473
    [Abstract] [Full Text] [Related]

  • 5. ROS and CHOP are critical for dibenzylideneacetone to sensitize tumor cells to TRAIL through induction of death receptors and downregulation of cell survival proteins.
    Prasad S, Yadav VR, Ravindran J, Aggarwal BB.
    Cancer Res; 2011 Jan 15; 71(2):538-49. PubMed ID: 21127198
    [Abstract] [Full Text] [Related]

  • 6. Cardamonin sensitizes tumour cells to TRAIL through ROS- and CHOP-mediated up-regulation of death receptors and down-regulation of survival proteins.
    Yadav VR, Prasad S, Aggarwal BB.
    Br J Pharmacol; 2012 Feb 15; 165(3):741-53. PubMed ID: 21797841
    [Abstract] [Full Text] [Related]

  • 7. Tanshinone IIA Facilitates TRAIL Sensitization by Up-regulating DR5 through the ROS-JNK-CHOP Signaling Axis in Human Ovarian Carcinoma Cell Lines.
    Chang CC, Kuan CP, Lin JY, Lai JS, Ho TF.
    Chem Res Toxicol; 2015 Aug 17; 28(8):1574-83. PubMed ID: 26203587
    [Abstract] [Full Text] [Related]

  • 8. Snake venom toxin from Vipera lebetina turanica sensitizes cancer cells to TRAIL through ROS- and JNK-mediated upregulation of death receptors and downregulation of survival proteins.
    Park MH, Jo M, Won D, Song HS, Song MJ, Hong JT.
    Apoptosis; 2012 Dec 17; 17(12):1316-26. PubMed ID: 23007278
    [Abstract] [Full Text] [Related]

  • 9. Zyflamend sensitizes tumor cells to TRAIL-induced apoptosis through up-regulation of death receptors and down-regulation of survival proteins: role of ROS-dependent CCAAT/enhancer-binding protein-homologous protein pathway.
    Kim JH, Park B, Gupta SC, Kannappan R, Sung B, Aggarwal BB.
    Antioxid Redox Signal; 2012 Mar 01; 16(5):413-27. PubMed ID: 22004570
    [Abstract] [Full Text] [Related]

  • 10. Kaempferol Sensitizes Human Ovarian Cancer Cells-OVCAR-3 and SKOV-3 to Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL)-Induced Apoptosis via JNK/ERK-CHOP Pathway and Up-Regulation of Death Receptors 4 and 5.
    Zhao Y, Tian B, Wang Y, Ding H.
    Med Sci Monit; 2017 Oct 26; 23():5096-5105. PubMed ID: 29070784
    [Abstract] [Full Text] [Related]

  • 11. Inhibition of euchromatin histone-lysine N-methyltransferase 2 sensitizes breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through reactive oxygen species-mediated activating transcription factor 4-C/EBP homologous protein-death receptor 5 pathway activation.
    Kim SY, Hong M, Heo SH, Park S, Kwon TK, Sung YH, Oh Y, Lee S, Yi GS, Kim I.
    Mol Carcinog; 2018 Nov 26; 57(11):1492-1506. PubMed ID: 29964331
    [Abstract] [Full Text] [Related]

  • 12. Verrucarin A sensitizes TRAIL-induced apoptosis via the upregulation of DR5 in an eIF2α/CHOP-dependent manner.
    Moon DO, Asami Y, Long H, Jang JH, Bae EY, Kim BY, Choi YH, Kang CH, Ahn JS, Kim GY.
    Toxicol In Vitro; 2013 Feb 26; 27(1):257-63. PubMed ID: 22982206
    [Abstract] [Full Text] [Related]

  • 13. 5, 7-Dimethoxyflavone sensitizes TRAIL-induced apoptosis through DR5 upregulation in hepatocellular carcinoma cells.
    Yang JF, Cao JG, Tian L, Liu F.
    Cancer Chemother Pharmacol; 2012 Jan 26; 69(1):195-206. PubMed ID: 21660448
    [Abstract] [Full Text] [Related]

  • 14. Role of endoplasmic reticulum stress in alpha-TEA mediated TRAIL/DR5 death receptor dependent apoptosis.
    Tiwary R, Yu W, Li J, Park SK, Sanders BG, Kline K.
    PLoS One; 2010 Jul 29; 5(7):e11865. PubMed ID: 20686688
    [Abstract] [Full Text] [Related]

  • 15. Ursolic acid, a pentacyclin triterpene, potentiates TRAIL-induced apoptosis through p53-independent up-regulation of death receptors: evidence for the role of reactive oxygen species and JNK.
    Prasad S, Yadav VR, Kannappan R, Aggarwal BB.
    J Biol Chem; 2011 Feb 18; 286(7):5546-57. PubMed ID: 21156789
    [Abstract] [Full Text] [Related]

  • 16. Medicarpin, a legume phytoalexin sensitizes myeloid leukemia cells to TRAIL-induced apoptosis through the induction of DR5 and activation of the ROS-JNK-CHOP pathway.
    Trivedi R, Maurya R, Mishra DP.
    Cell Death Dis; 2014 Oct 16; 5(10):e1465. PubMed ID: 25321472
    [Abstract] [Full Text] [Related]

  • 17. The herbal compound cryptotanshinone restores sensitivity in cancer cells that are resistant to the tumor necrosis factor-related apoptosis-inducing ligand.
    Tse AK, Chow KY, Cao HH, Cheng CY, Kwan HY, Yu H, Zhu GY, Wu YC, Fong WF, Yu ZL.
    J Biol Chem; 2013 Oct 11; 288(41):29923-33. PubMed ID: 23986445
    [Abstract] [Full Text] [Related]

  • 18. Ginsenoside compound K sensitizes human colon cancer cells to TRAIL-induced apoptosis via autophagy-dependent and -independent DR5 upregulation.
    Chen L, Meng Y, Sun Q, Zhang Z, Guo X, Sheng X, Tai G, Cheng H, Zhou Y.
    Cell Death Dis; 2016 Aug 11; 7(8):e2334. PubMed ID: 27512955
    [Abstract] [Full Text] [Related]

  • 19. Garcinol potentiates TRAIL-induced apoptosis through modulation of death receptors and antiapoptotic proteins.
    Prasad S, Ravindran J, Sung B, Pandey MK, Aggarwal BB.
    Mol Cancer Ther; 2010 Apr 11; 9(4):856-68. PubMed ID: 20371723
    [Abstract] [Full Text] [Related]

  • 20. Guggulsterone sensitizes hepatoma cells to TRAIL-induced apoptosis through the induction of CHOP-dependent DR5: involvement of ROS-dependent ER-stress.
    Moon DO, Park SY, Choi YH, Ahn JS, Kim GY.
    Biochem Pharmacol; 2011 Dec 01; 82(11):1641-50. PubMed ID: 21903093
    [Abstract] [Full Text] [Related]

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