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222 related items for PubMed ID: 22926525

  • 1. Histone methylase MLL1 has critical roles in tumor growth and angiogenesis and its knockdown suppresses tumor growth in vivo.
    Ansari KI, Kasiri S, Mandal SS.
    Oncogene; 2013 Jul 11; 32(28):3359-70. PubMed ID: 22926525
    [Abstract] [Full Text] [Related]

  • 2. Histone methylase MLL1 coordinates with HIF and regulate lncRNA HOTAIR expression under hypoxia.
    Bhan A, Deb P, Shihabeddin N, Ansari KI, Brotto M, Mandal SS.
    Gene; 2017 Sep 20; 629():16-28. PubMed ID: 28756022
    [Abstract] [Full Text] [Related]

  • 3. Overexpression of human histone methylase MLL1 upon exposure to a food contaminant mycotoxin, deoxynivalenol.
    Ansari KI, Hussain I, Das HK, Mandal SS.
    FEBS J; 2009 Jun 20; 276(12):3299-307. PubMed ID: 19438726
    [Abstract] [Full Text] [Related]

  • 4. Mixed lineage leukaemia-4 regulates cell-cycle progression and cell viability and its depletion suppresses growth of xenografted tumour in vivo.
    Ansari KI, Kasiri S, Mishra BP, Mandal SS.
    Br J Cancer; 2012 Jul 10; 107(2):315-24. PubMed ID: 22713656
    [Abstract] [Full Text] [Related]

  • 5. MLL1 is essential for the senescence-associated secretory phenotype.
    Capell BC, Drake AM, Zhu J, Shah PP, Dou Z, Dorsey J, Simola DF, Donahue G, Sammons M, Rai TS, Natale C, Ridky TW, Adams PD, Berger SL.
    Genes Dev; 2016 Feb 01; 30(3):321-36. PubMed ID: 26833731
    [Abstract] [Full Text] [Related]

  • 6. Epigenetic drug screening for trophoblast syncytialization reveals a novel role for MLL1 in regulating fetoplacental growth.
    Wu J, Qin C, Tian F, Liu X, Hu J, Wu F, Chen C, Lin Y.
    BMC Med; 2024 Feb 05; 22(1):57. PubMed ID: 38317232
    [Abstract] [Full Text] [Related]

  • 7. Antisense transcript long noncoding RNA (lncRNA) HOTAIR is transcriptionally induced by estradiol.
    Bhan A, Hussain I, Ansari KI, Kasiri S, Bashyal A, Mandal SS.
    J Mol Biol; 2013 Oct 09; 425(19):3707-22. PubMed ID: 23375982
    [Abstract] [Full Text] [Related]

  • 8. miR-193a targets MLL1 mRNA and drastically decreases MLL1 protein production: Ectopic expression of the miRNA aberrantly lowers H3K4me3 content of the chromatin and hampers cell proliferation and viability.
    Sengupta D, Deb M, Kar S, Parbin S, Pradhan N, Patra SK.
    Gene; 2019 Jul 15; 705():22-35. PubMed ID: 31005612
    [Abstract] [Full Text] [Related]

  • 9. Hypoxia-induced mixed-lineage leukemia 1 regulates glioma stem cell tumorigenic potential.
    Heddleston JM, Wu Q, Rivera M, Minhas S, Lathia JD, Sloan AE, Iliopoulos O, Hjelmeland AB, Rich JN.
    Cell Death Differ; 2012 Mar 15; 19(3):428-39. PubMed ID: 21836617
    [Abstract] [Full Text] [Related]

  • 10. Neuronal Kmt2a/Mll1 histone methyltransferase is essential for prefrontal synaptic plasticity and working memory.
    Jakovcevski M, Ruan H, Shen EY, Dincer A, Javidfar B, Ma Q, Peter CJ, Cheung I, Mitchell AC, Jiang Y, Lin CL, Pothula V, Stewart AF, Ernst P, Yao WD, Akbarian S.
    J Neurosci; 2015 Apr 01; 35(13):5097-108. PubMed ID: 25834037
    [Abstract] [Full Text] [Related]

  • 11. Piribedil disrupts the MLL1-WDR5 interaction and sensitizes MLL-rearranged acute myeloid leukemia (AML) to doxorubicin-induced apoptosis.
    Zhang X, Zheng X, Yang H, Yan J, Fu X, Wei R, Xu X, Zhang Z, Yu A, Zhou K, Ding J, Geng M, Huang X.
    Cancer Lett; 2018 Sep 01; 431():150-160. PubMed ID: 29857126
    [Abstract] [Full Text] [Related]

  • 12. Tumorigenicity of Ewing sarcoma is critically dependent on the trithorax proteins MLL1 and menin.
    Svoboda LK, Bailey N, Van Noord RA, Krook MA, Harris A, Cramer C, Jasman B, Patel RM, Thomas D, Borkin D, Cierpicki T, Grembecka J, Lawlor ER.
    Oncotarget; 2017 Jan 03; 8(1):458-471. PubMed ID: 27888797
    [Abstract] [Full Text] [Related]

  • 13. MLL1, a H3K4 methyltransferase, regulates the TNFα-stimulated activation of genes downstream of NF-κB.
    Wang X, Zhu K, Li S, Liao Y, Du R, Zhang X, Shu HB, Guo AY, Li L, Wu M.
    J Cell Sci; 2012 Sep 01; 125(Pt 17):4058-66. PubMed ID: 22623725
    [Abstract] [Full Text] [Related]

  • 14. Human CpG binding protein interacts with MLL1, MLL2 and hSet1 and regulates Hox gene expression.
    Ansari KI, Mishra BP, Mandal SS.
    Biochim Biophys Acta; 2008 Jan 01; 1779(1):66-73. PubMed ID: 18082152
    [Abstract] [Full Text] [Related]

  • 15. MLL1 promotes myogenesis by epigenetically regulating Myf5.
    Cai S, Zhu Q, Guo C, Yuan R, Zhang X, Nie Y, Chen L, Fang Y, Chen K, Zhang J, Mo D, Chen Y.
    Cell Prolif; 2020 Feb 01; 53(2):e12744. PubMed ID: 31840352
    [Abstract] [Full Text] [Related]

  • 16. Cell context in the control of self-renewal and proliferation regulated by MLL1.
    Artinger EL, Ernst P.
    Cell Cycle; 2013 Sep 15; 12(18):2969-72. PubMed ID: 23974107
    [Abstract] [Full Text] [Related]

  • 17. The many facets of MLL1 regulation.
    Zhang P, Bergamin E, Couture JF.
    Biopolymers; 2013 Feb 15; 99(2):136-45. PubMed ID: 23175388
    [Abstract] [Full Text] [Related]

  • 18. Histone methyltransferase MLL1 regulates MDR1 transcription and chemoresistance.
    Huo H, Magro PG, Pietsch EC, Patel BB, Scotto KW.
    Cancer Res; 2010 Nov 01; 70(21):8726-35. PubMed ID: 20861184
    [Abstract] [Full Text] [Related]

  • 19. Mixed lineage leukemia: roles in gene expression, hormone signaling and mRNA processing.
    Ansari KI, Mandal SS.
    FEBS J; 2010 Apr 01; 277(8):1790-804. PubMed ID: 20236313
    [Abstract] [Full Text] [Related]

  • 20. An aberrantly sustained emergency granulopoiesis response accelerates postchemotherapy relapse in MLL1-rearranged acute myeloid leukemia in mice.
    Wang H, Shah CA, Hu L, Huang W, Platanias LC, Eklund EA.
    J Biol Chem; 2020 Jul 10; 295(28):9663-9675. PubMed ID: 32467231
    [Abstract] [Full Text] [Related]

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