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388 related items for PubMed ID: 22927446

  • 1. Autophagy-related gene 7 (ATG7) and reactive oxygen species/extracellular signal-regulated kinase regulate tetrandrine-induced autophagy in human hepatocellular carcinoma.
    Gong K, Chen C, Zhan Y, Chen Y, Huang Z, Li W.
    J Biol Chem; 2012 Oct 12; 287(42):35576-35588. PubMed ID: 22927446
    [Abstract] [Full Text] [Related]

  • 2. Tetrandrine induces apoptosis by activating reactive oxygen species and repressing Akt activity in human hepatocellular carcinoma.
    Liu C, Gong K, Mao X, Li W.
    Int J Cancer; 2011 Sep 15; 129(6):1519-31. PubMed ID: 21128229
    [Abstract] [Full Text] [Related]

  • 3. Extracellular signal-regulated kinase, receptor interacting protein, and reactive oxygen species regulate shikonin-induced autophagy in human hepatocellular carcinoma.
    Gong K, Zhang Z, Chen Y, Shu HB, Li W.
    Eur J Pharmacol; 2014 Sep 05; 738():142-52. PubMed ID: 24886888
    [Abstract] [Full Text] [Related]

  • 4. The plant alkaloid tetrandrine inhibits metastasis via autophagy-dependent Wnt/β-catenin and metastatic tumor antigen 1 signaling in human liver cancer cells.
    Zhang Z, Liu T, Yu M, Li K, Li W.
    J Exp Clin Cancer Res; 2018 Jan 15; 37(1):7. PubMed ID: 29334999
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  • 5. Synergistic anti-tumour effects of tetrandrine and chloroquine combination therapy in human cancer: a potential antagonistic role for p21.
    Mei L, Chen Y, Wang Z, Wang J, Wan J, Yu C, Liu X, Li W.
    Br J Pharmacol; 2015 May 15; 172(9):2232-45. PubMed ID: 25521075
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma.
    Shimizu S, Takehara T, Hikita H, Kodama T, Tsunematsu H, Miyagi T, Hosui A, Ishida H, Tatsumi T, Kanto T, Hiramatsu N, Fujita N, Yoshimori T, Hayashi N.
    Int J Cancer; 2012 Aug 01; 131(3):548-57. PubMed ID: 21858812
    [Abstract] [Full Text] [Related]

  • 7. Synergistic antitumour activity of sorafenib in combination with tetrandrine is mediated by reactive oxygen species (ROS)/Akt signaling.
    Wan J, Liu T, Mei L, Li J, Gong K, Yu C, Li W.
    Br J Cancer; 2013 Jul 23; 109(2):342-50. PubMed ID: 23807172
    [Abstract] [Full Text] [Related]

  • 8. P38 MAP kinase functions as a switch in MS-275-induced reactive oxygen species-dependent autophagy and apoptosis in human colon cancer cells.
    Zhan Y, Gong K, Chen C, Wang H, Li W.
    Free Radic Biol Med; 2012 Aug 01; 53(3):532-43. PubMed ID: 22634147
    [Abstract] [Full Text] [Related]

  • 9. Autophagy induction enhances tetrandrine-induced apoptosis via the AMPK/mTOR pathway in human bladder cancer cells.
    Kou B, Liu W, Xu X, Yang Y, Yi Q, Guo F, Li J, Zhou J, Kou Q.
    Oncol Rep; 2017 Nov 01; 38(5):3137-3143. PubMed ID: 29048631
    [Abstract] [Full Text] [Related]

  • 10. Combination therapy with protein kinase inhibitor H89 and Tetrandrine elicits enhanced synergistic antitumor efficacy.
    Yu M, Liu T, Chen Y, Li Y, Li W.
    J Exp Clin Cancer Res; 2018 Jun 04; 37(1):114. PubMed ID: 29866132
    [Abstract] [Full Text] [Related]

  • 11. Lapatinib induces autophagic cell death and inhibits growth of human hepatocellular carcinoma.
    Chen YJ, Chi CW, Su WC, Huang HL.
    Oncotarget; 2014 Jul 15; 5(13):4845-54. PubMed ID: 24947784
    [Abstract] [Full Text] [Related]

  • 12. Longikaurin A, a natural ent-kaurane, induces G2/M phase arrest via downregulation of Skp2 and apoptosis induction through ROS/JNK/c-Jun pathway in hepatocellular carcinoma cells.
    Liao YJ, Bai HY, Li ZH, Zou J, Chen JW, Zheng F, Zhang JX, Mai SJ, Zeng MS, Sun HD, Pu JX, Xie D.
    Cell Death Dis; 2014 Mar 20; 5(3):e1137. PubMed ID: 24651440
    [Abstract] [Full Text] [Related]

  • 13. β-Thujaplicin induces autophagic cell death, apoptosis, and cell cycle arrest through ROS-mediated Akt and p38/ERK MAPK signaling in human hepatocellular carcinoma.
    Zhang G, He J, Ye X, Zhu J, Hu X, Shen M, Ma Y, Mao Z, Song H, Chen F.
    Cell Death Dis; 2019 Mar 15; 10(4):255. PubMed ID: 30874538
    [Abstract] [Full Text] [Related]

  • 14. Inhibition of autophagic flux by salinomycin results in anti-cancer effect in hepatocellular carcinoma cells.
    Klose J, Stankov MV, Kleine M, Ramackers W, Panayotova-Dimitrova D, Jäger MD, Klempnauer J, Winkler M, Bektas H, Behrens GM, Vondran FW.
    PLoS One; 2014 Mar 15; 9(5):e95970. PubMed ID: 24816744
    [Abstract] [Full Text] [Related]

  • 15. GL-V9 induced upregulation and mitochondrial localization of NAG-1 associates with ROS generation and cell death in hepatocellular carcinoma cells.
    Zhang X, Kang Y, Huo T, Tao R, Wang X, Li Z, Guo Q, Zhao L.
    Free Radic Biol Med; 2017 Nov 15; 112():49-59. PubMed ID: 28697922
    [Abstract] [Full Text] [Related]

  • 16. Calf Spleen Extractive Injection (CSEI), a small peptides enriched extraction, induces human hepatocellular carcinoma cell apoptosis via ROS/MAPKs dependent mitochondrial pathway.
    Jia D, Lu W, Zhang X, Cai G, Teng L, Wang X, Zhang M, Zeng Y, Liang C, Wang D.
    J Pharmacol Sci; 2016 Oct 15; 132(2):122-130. PubMed ID: 28314430
    [Abstract] [Full Text] [Related]

  • 17. Tetrandrine induces autophagy and differentiation by activating ROS and Notch1 signaling in leukemia cells.
    Liu T, Men Q, Wu G, Yu C, Huang Z, Liu X, Li W.
    Oncotarget; 2015 Apr 10; 6(10):7992-8006. PubMed ID: 25797266
    [Abstract] [Full Text] [Related]

  • 18. Coptisine induces autophagic cell death through down-regulation of PI3K/Akt/mTOR signaling pathway and up-regulation of ROS-mediated mitochondrial dysfunction in hepatocellular carcinoma Hep3B cells.
    Kim SY, Hwangbo H, Kim MY, Ji SY, Lee H, Kim GY, Kwon CY, Leem SH, Hong SH, Cheong J, Choi YH.
    Arch Biochem Biophys; 2021 Jan 15; 697():108688. PubMed ID: 33227289
    [Abstract] [Full Text] [Related]

  • 19. Bafilomycin A1 induces caspase-independent cell death in hepatocellular carcinoma cells via targeting of autophagy and MAPK pathways.
    Yan Y, Jiang K, Liu P, Zhang X, Dong X, Gao J, Liu Q, Barr MP, Zhang Q, Hou X, Meng S, Gong P.
    Sci Rep; 2016 Nov 15; 6():37052. PubMed ID: 27845389
    [Abstract] [Full Text] [Related]

  • 20. Tetrandrine induces programmed cell death in human oral cancer CAL 27 cells through the reactive oxygen species production and caspase-dependent pathways and associated with beclin-1-induced cell autophagy.
    Lien JC, Lin MW, Chang SJ, Lai KC, Huang AC, Yu FS, Chung JG.
    Environ Toxicol; 2017 Jan 15; 32(1):329-343. PubMed ID: 26822499
    [Abstract] [Full Text] [Related]

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