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Journal Abstract Search

402 related items for PubMed ID: 22932900

  • 1. Activation of peroxisome proliferator-activated receptor α (PPARα) suppresses hypoxia-inducible factor-1α (HIF-1α) signaling in cancer cells.
    Zhou J, Zhang S, Xue J, Avery J, Wu J, Lind SE, Ding WQ.
    J Biol Chem; 2012 Oct 12; 287(42):35161-35169. PubMed ID: 22932900
    [Abstract] [Full Text] [Related]

  • 2. Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway.
    Carroll VA, Ashcroft M.
    Cancer Res; 2006 Jun 15; 66(12):6264-70. PubMed ID: 16778202
    [Abstract] [Full Text] [Related]

  • 3. Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3'-kinase/Akt signaling pathway.
    Blancher C, Moore JW, Robertson N, Harris AL.
    Cancer Res; 2001 Oct 01; 61(19):7349-55. PubMed ID: 11585776
    [Abstract] [Full Text] [Related]

  • 4. Prolyl hydroxylase 2 dependent and Von-Hippel-Lindau independent degradation of Hypoxia-inducible factor 1 and 2 alpha by selenium in clear cell renal cell carcinoma leads to tumor growth inhibition.
    Chintala S, Najrana T, Toth K, Cao S, Durrani FA, Pili R, Rustum YM.
    BMC Cancer; 2012 Jul 17; 12():293. PubMed ID: 22804960
    [Abstract] [Full Text] [Related]

  • 5. HIF-1α/GPER signaling mediates the expression of VEGF induced by hypoxia in breast cancer associated fibroblasts (CAFs).
    De Francesco EM, Lappano R, Santolla MF, Marsico S, Caruso A, Maggiolini M.
    Breast Cancer Res; 2013 Jul 17; 15(4):R64. PubMed ID: 23947803
    [Abstract] [Full Text] [Related]

  • 6. Antiangiogenic activity of phthalides-enriched Angelica Sinensis extract by suppressing WSB-1/pVHL/HIF-1α/VEGF signaling in bladder cancer.
    Chen MC, Hsu WL, Chang WL, Chou TC.
    Sci Rep; 2017 Jul 14; 7(1):5376. PubMed ID: 28710377
    [Abstract] [Full Text] [Related]

  • 7. Rhapontigenin inhibited hypoxia inducible factor 1 alpha accumulation and angiogenesis in hypoxic PC-3 prostate cancer cells.
    Jung DB, Lee HJ, Jeong SJ, Lee HJ, Lee EO, Kim YC, Ahn KS, Chen CY, Kim SH.
    Biol Pharm Bull; 2011 Jul 14; 34(6):850-5. PubMed ID: 21628883
    [Abstract] [Full Text] [Related]

  • 8. Estrogen receptor α is a novel target of the Von Hippel-Lindau protein and is responsible for the proliferation of VHL-deficient cells under hypoxic conditions.
    Jung YS, Lee SJ, Yoon MH, Ha NC, Park BJ.
    Cell Cycle; 2012 Dec 01; 11(23):4462-73. PubMed ID: 23159849
    [Abstract] [Full Text] [Related]

  • 9. trans-3,4,5'-Trihydroxystibene inhibits hypoxia-inducible factor 1alpha and vascular endothelial growth factor expression in human ovarian cancer cells.
    Cao Z, Fang J, Xia C, Shi X, Jiang BH.
    Clin Cancer Res; 2004 Aug 01; 10(15):5253-63. PubMed ID: 15297429
    [Abstract] [Full Text] [Related]

  • 10. Activation of hypoxia-induced transcription in normoxia.
    Hägg M, Wennström S.
    Exp Cell Res; 2005 May 15; 306(1):180-91. PubMed ID: 15878343
    [Abstract] [Full Text] [Related]

  • 11. Expression of hypoxia-inducible factor 1alpha, hypoxia-inducible factor 2alpha, and von Hippel-Lindau protein in epithelial ovarian neoplasms and allelic loss of von Hippel-Lindau gene: nuclear expression of hypoxia-inducible factor 1alpha is an independent prognostic factor in ovarian carcinoma.
    Osada R, Horiuchi A, Kikuchi N, Yoshida J, Hayashi A, Ota M, Katsuyama Y, Melillo G, Konishi I.
    Hum Pathol; 2007 Sep 15; 38(9):1310-20. PubMed ID: 17555795
    [Abstract] [Full Text] [Related]

  • 12. PPARα regulates mobilization and homing of endothelial progenitor cells through the HIF-1α/SDF-1 pathway.
    Wang Z, Moran E, Ding L, Cheng R, Xu X, Ma JX.
    Invest Ophthalmol Vis Sci; 2014 May 20; 55(6):3820-32. PubMed ID: 24845641
    [Abstract] [Full Text] [Related]

  • 13. Runx2 protein stabilizes hypoxia-inducible factor-1α through competition with von Hippel-Lindau protein (pVHL) and stimulates angiogenesis in growth plate hypertrophic chondrocytes.
    Lee SH, Che X, Jeong JH, Choi JY, Lee YJ, Lee YH, Bae SC, Lee YM.
    J Biol Chem; 2012 Apr 27; 287(18):14760-71. PubMed ID: 22351759
    [Abstract] [Full Text] [Related]

  • 14. GPER mediates the angiocrine actions induced by IGF1 through the HIF-1α/VEGF pathway in the breast tumor microenvironment.
    De Francesco EM, Sims AH, Maggiolini M, Sotgia F, Lisanti MP, Clarke RB.
    Breast Cancer Res; 2017 Dec 06; 19(1):129. PubMed ID: 29212519
    [Abstract] [Full Text] [Related]

  • 15. Wogonin inhibits tumor angiogenesis via degradation of HIF-1α protein.
    Song X, Yao J, Wang F, Zhou M, Zhou Y, Wang H, Wei L, Zhao L, Li Z, Lu N, Guo Q.
    Toxicol Appl Pharmacol; 2013 Sep 01; 271(2):144-55. PubMed ID: 23707765
    [Abstract] [Full Text] [Related]

  • 16. COMMD1 Promotes pVHL and O2-Independent Proteolysis of HIF-1alpha via HSP90/70.
    van de Sluis B, Groot AJ, Vermeulen J, van der Wall E, van Diest PJ, Wijmenga C, Klomp LW, Vooijs M.
    PLoS One; 2009 Oct 05; 4(10):e7332. PubMed ID: 19802386
    [Abstract] [Full Text] [Related]

  • 17. Apolipoprotein A-I mimetic peptides inhibit expression and activity of hypoxia-inducible factor-1α in human ovarian cancer cell lines and a mouse ovarian cancer model.
    Gao F, Chattopadhyay A, Navab M, Grijalva V, Su F, Fogelman AM, Reddy ST, Farias-Eisner R.
    J Pharmacol Exp Ther; 2012 Aug 05; 342(2):255-62. PubMed ID: 22537771
    [Abstract] [Full Text] [Related]

  • 18. Flavonoids-induced accumulation of hypoxia-inducible factor (HIF)-1alpha/2alpha is mediated through chelation of iron.
    Park SS, Bae I, Lee YJ.
    J Cell Biochem; 2008 Apr 15; 103(6):1989-98. PubMed ID: 17973296
    [Abstract] [Full Text] [Related]

  • 19. Identification of an alternative mechanism of degradation of the hypoxia-inducible factor-1alpha.
    André H, Pereira TS.
    J Biol Chem; 2008 Oct 24; 283(43):29375-84. PubMed ID: 18694926
    [Abstract] [Full Text] [Related]

  • 20. iASPP is essential for HIF-1α stabilization to promote angiogenesis and glycolysis via attenuating VHL-mediated protein degradation.
    Zhao D, Zheng S, Wang X, Liu H, Zhao K, Li L, Hu Y.
    Oncogene; 2022 Mar 24; 41(13):1944-1958. PubMed ID: 35169254
    [Abstract] [Full Text] [Related]

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