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584 related items for PubMed ID: 22943175

  • 1. In-vitro metabolism of glycyrrhetinic acid by human and rat liver microsomes and its interactions with six CYP substrates.
    Zhao K, Ding M, Cao H, Cao ZX.
    J Pharm Pharmacol; 2012 Oct; 64(10):1445-51. PubMed ID: 22943175
    [Abstract] [Full Text] [Related]

  • 2. In vitro metabolism of fipronil by human and rat cytochrome P450 and its interactions with testosterone and diazepam.
    Tang J, Amin Usmani K, Hodgson E, Rose RL.
    Chem Biol Interact; 2004 Apr 15; 147(3):319-29. PubMed ID: 15135087
    [Abstract] [Full Text] [Related]

  • 3. Isoniazid is a mechanism-based inhibitor of cytochrome P450 1A2, 2A6, 2C19 and 3A4 isoforms in human liver microsomes.
    Wen X, Wang JS, Neuvonen PJ, Backman JT.
    Eur J Clin Pharmacol; 2002 Jan 15; 57(11):799-804. PubMed ID: 11868802
    [Abstract] [Full Text] [Related]

  • 4. Gemfibrozil is a potent inhibitor of human cytochrome P450 2C9.
    Wen X, Wang JS, Backman JT, Kivistö KT, Neuvonen PJ.
    Drug Metab Dispos; 2001 Nov 15; 29(11):1359-61. PubMed ID: 11602509
    [Abstract] [Full Text] [Related]

  • 5. Roles of CYP3A4 and CYP2C19 in methyl hydroxylated and N-oxidized metabolite formation from voriconazole, a new anti-fungal agent, in human liver microsomes.
    Murayama N, Imai N, Nakane T, Shimizu M, Yamazaki H.
    Biochem Pharmacol; 2007 Jun 15; 73(12):2020-6. PubMed ID: 17433262
    [Abstract] [Full Text] [Related]

  • 6. In vitro metabolism of glycyrrhetic acid by human cytochrome P450.
    Liu L, Xiao J, Peng ZH, Chen Y.
    Yao Xue Xue Bao; 2011 Jan 15; 46(1):81-7. PubMed ID: 21462897
    [Abstract] [Full Text] [Related]

  • 7. The inhibitory effect of polyunsaturated fatty acids on human CYP enzymes.
    Yao HT, Chang YW, Lan SJ, Chen CT, Hsu JT, Yeh TK.
    Life Sci; 2006 Nov 25; 79(26):2432-40. PubMed ID: 16978661
    [Abstract] [Full Text] [Related]

  • 8. The role of CYP2C in the in vitro bioactivation of the contraceptive steroid desogestrel.
    Gentile DM, Verhoeven CH, Shimada T, Back DJ.
    J Pharmacol Exp Ther; 1998 Dec 25; 287(3):975-82. PubMed ID: 9864282
    [Abstract] [Full Text] [Related]

  • 9. Progesterone and testosterone hydroxylation by cytochromes P450 2C19, 2C9, and 3A4 in human liver microsomes.
    Yamazaki H, Shimada T.
    Arch Biochem Biophys; 1997 Oct 01; 346(1):161-9. PubMed ID: 9328296
    [Abstract] [Full Text] [Related]

  • 10. Characterization of CYP2C19 and CYP2C9 from human liver: respective roles in microsomal tolbutamide, S-mephenytoin, and omeprazole hydroxylations.
    Lasker JM, Wester MR, Aramsombatdee E, Raucy JL.
    Arch Biochem Biophys; 1998 May 01; 353(1):16-28. PubMed ID: 9578596
    [Abstract] [Full Text] [Related]

  • 11. Differential selectivity of cytochrome P450 inhibitors against probe substrates in human and rat liver microsomes.
    Eagling VA, Tjia JF, Back DJ.
    Br J Clin Pharmacol; 1998 Feb 01; 45(2):107-14. PubMed ID: 9491822
    [Abstract] [Full Text] [Related]

  • 12. Interactions between CYP2C9 and CYP2C19 in reconstituted binary systems influence their catalytic activity: possible rationale for the inability of CYP2C19 to catalyze methoxychlor demethylation in human liver microsomes.
    Hazai E, Kupfer D.
    Drug Metab Dispos; 2005 Jan 01; 33(1):157-64. PubMed ID: 15486075
    [Abstract] [Full Text] [Related]

  • 13. The inhibitory effect of tannic acid on cytochrome P450 enzymes and NADPH-CYP reductase in rat and human liver microsomes.
    Yao HT, Chang YW, Lan SJ, Yeh TK.
    Food Chem Toxicol; 2008 Feb 01; 46(2):645-53. PubMed ID: 17950511
    [Abstract] [Full Text] [Related]

  • 14. Identification of human cytochrome P450 isoforms involved in the 3-hydroxylation of quinine by human live microsomes and nine recombinant human cytochromes P450.
    Zhao XJ, Yokoyama H, Chiba K, Wanwimolruk S, Ishizaki T.
    J Pharmacol Exp Ther; 1996 Dec 01; 279(3):1327-34. PubMed ID: 8968357
    [Abstract] [Full Text] [Related]

  • 15. In vitro characterization of sarizotan metabolism: hepatic clearance, identification and characterization of metabolites, drug-metabolizing enzyme identification, and evaluation of cytochrome p450 inhibition.
    Gallemann D, Wimmer E, Höfer CC, Freisleben A, Fluck M, Ladstetter B, Dolgos H.
    Drug Metab Dispos; 2010 Jun 01; 38(6):905-16. PubMed ID: 20219851
    [Abstract] [Full Text] [Related]

  • 16. An automated, high-throughput, 384 well Cytochrome P450 cocktail IC50 assay using a rapid resolution LC-MS/MS end-point.
    Youdim KA, Lyons R, Payne L, Jones BC, Saunders K.
    J Pharm Biomed Anal; 2008 Sep 10; 48(1):92-9. PubMed ID: 18584988
    [Abstract] [Full Text] [Related]

  • 17. Substrate specificity for rat cytochrome P450 (CYP) isoforms: screening with cDNA-expressed systems of the rat.
    Kobayashi K, Urashima K, Shimada N, Chiba K.
    Biochem Pharmacol; 2002 Mar 01; 63(5):889-96. PubMed ID: 11911841
    [Abstract] [Full Text] [Related]

  • 18. In vitro metabolism of carbofuran by human, mouse, and rat cytochrome P450 and interactions with chlorpyrifos, testosterone, and estradiol.
    Usmani KA, Hodgson E, Rose RL.
    Chem Biol Interact; 2004 Dec 07; 150(3):221-32. PubMed ID: 15560889
    [Abstract] [Full Text] [Related]

  • 19. Major role of human liver microsomal cytochrome P450 2C9 (CYP2C9) in the oxidative metabolism of celecoxib, a novel cyclooxygenase-II inhibitor.
    Tang C, Shou M, Mei Q, Rushmore TH, Rodrigues AD.
    J Pharmacol Exp Ther; 2000 May 07; 293(2):453-9. PubMed ID: 10773015
    [Abstract] [Full Text] [Related]

  • 20. CYP2B6, CYP3A4, and CYP2C19 are responsible for the in vitro N-demethylation of meperidine in human liver microsomes.
    Ramírez J, Innocenti F, Schuetz EG, Flockhart DA, Relling MV, Santucci R, Ratain MJ.
    Drug Metab Dispos; 2004 Sep 07; 32(9):930-6. PubMed ID: 15319333
    [Abstract] [Full Text] [Related]

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