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446 related items for PubMed ID: 22948392

  • 1. Suppression of HSP70 expression sensitizes NSCLC cell lines to TRAIL-induced apoptosis by upregulating DR4 and DR5 and downregulating c-FLIP-L expressions.
    Zhuang H, Jiang W, Zhang X, Qiu F, Gan Z, Cheng W, Zhang J, Guan S, Tang B, Huang Q, Wu X, Huang X, Jiang W, Hu Q, Lu M, Hua ZC.
    J Mol Med (Berl); 2013 Feb; 91(2):219-35. PubMed ID: 22948392
    [Abstract] [Full Text] [Related]

  • 2. Dissecting the roles of DR4, DR5 and c-FLIP in the regulation of geranylgeranyltransferase I inhibition-mediated augmentation of TRAIL-induced apoptosis.
    Chen S, Fu L, Raja SM, Yue P, Khuri FR, Sun SY.
    Mol Cancer; 2010 Jan 29; 9():23. PubMed ID: 20113484
    [Abstract] [Full Text] [Related]

  • 3. The proteasome inhibitor PS-341 (bortezomib) up-regulates DR5 expression leading to induction of apoptosis and enhancement of TRAIL-induced apoptosis despite up-regulation of c-FLIP and survivin expression in human NSCLC cells.
    Liu X, Yue P, Chen S, Hu L, Lonial S, Khuri FR, Sun SY.
    Cancer Res; 2007 May 15; 67(10):4981-8. PubMed ID: 17510429
    [Abstract] [Full Text] [Related]

  • 4. Phytosphingosine in combination with TRAIL sensitizes cancer cells to TRAIL through synergistic up-regulation of DR4 and DR5.
    Choi SY, Kim MJ, Chung HY, Lee SJ, Jang YJ.
    Oncol Rep; 2007 Jan 15; 17(1):175-84. PubMed ID: 17143496
    [Abstract] [Full Text] [Related]

  • 5. Pifithrin-μ is efficacious against non-small cell lung cancer via inhibition of heat shock protein 70.
    Zhou Y, Ma J, Zhang J, He L, Gong J, Long C.
    Oncol Rep; 2017 Jan 15; 37(1):313-322. PubMed ID: 28004121
    [Abstract] [Full Text] [Related]

  • 6. Apigenin potentiates TRAIL therapy of non-small cell lung cancer via upregulating DR4/DR5 expression in a p53-dependent manner.
    Chen M, Wang X, Zha D, Cai F, Zhang W, He Y, Huang Q, Zhuang H, Hua ZC.
    Sci Rep; 2016 Oct 18; 6():35468. PubMed ID: 27752089
    [Abstract] [Full Text] [Related]

  • 7. Short-hairpin RNA-induced suppression of adenine nucleotide translocase-2 in breast cancer cells restores their susceptibility to TRAIL-induced apoptosis by activating JNK and modulating TRAIL receptor expression.
    Jang JY, Jeon YK, Choi Y, Kim CW.
    Mol Cancer; 2010 Sep 28; 9():262. PubMed ID: 20875141
    [Abstract] [Full Text] [Related]

  • 8. ABT-737 induces expression of the death receptor 5 and sensitizes human cancer cells to TRAIL-induced apoptosis.
    Song JH, Kandasamy K, Kraft AS.
    J Biol Chem; 2008 Sep 05; 283(36):25003-13. PubMed ID: 18599488
    [Abstract] [Full Text] [Related]

  • 9. CCAAT/enhancer binding protein homologous protein-dependent death receptor 5 induction and ubiquitin/proteasome-mediated cellular FLICE-inhibitory protein down-regulation contribute to enhancement of tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by dimethyl-celecoxib in human non small-cell lung cancer cells.
    Chen S, Liu X, Yue P, Schönthal AH, Khuri FR, Sun SY.
    Mol Pharmacol; 2007 Nov 05; 72(5):1269-79. PubMed ID: 17684158
    [Abstract] [Full Text] [Related]

  • 10. Inhibition of ataxia telangiectasia mutated kinase activity enhances TRAIL-mediated apoptosis in human melanoma cells.
    Ivanov VN, Zhou H, Partridge MA, Hei TK.
    Cancer Res; 2009 Apr 15; 69(8):3510-9. PubMed ID: 19351839
    [Abstract] [Full Text] [Related]

  • 11. The alkylphospholipid perifosine induces apoptosis of human lung cancer cells requiring inhibition of Akt and activation of the extrinsic apoptotic pathway.
    Elrod HA, Lin YD, Yue P, Wang X, Lonial S, Khuri FR, Sun SY.
    Mol Cancer Ther; 2007 Jul 15; 6(7):2029-38. PubMed ID: 17604333
    [Abstract] [Full Text] [Related]

  • 12. Upregulation of c-FLIP-short in response to TRAIL promotes survival of NSCLC cells, which could be suppressed by inhibition of Ca2+/calmodulin signaling.
    Kaminskyy VO, Surova OV, Piskunova T, Zborovskaya IB, Tchevkina EM, Andera L, Zhivotovsky B.
    Cell Death Dis; 2013 Mar 07; 4(3):e522. PubMed ID: 23470529
    [Abstract] [Full Text] [Related]

  • 13. N-Acetyl-Glucosamine Sensitizes Non-Small Cell Lung Cancer Cells to TRAIL-Induced Apoptosis by Activating Death Receptor 5.
    Liang Y, Xu W, Liu S, Chi J, Zhang J, Sui A, Wang L, Liang Z, Li D, Chen Y, Niu H.
    Cell Physiol Biochem; 2018 Mar 07; 45(5):2054-2070. PubMed ID: 29533936
    [Abstract] [Full Text] [Related]

  • 14. PPARgamma ligands enhance TRAIL-induced apoptosis through DR5 upregulation and c-FLIP downregulation in human lung cancer cells.
    Zou W, Liu X, Yue P, Khuri FR, Sun SY.
    Cancer Biol Ther; 2007 Jan 07; 6(1):99-106. PubMed ID: 17172826
    [Abstract] [Full Text] [Related]

  • 15. Procaspase 8 overexpression in non-small-cell lung cancer promotes apoptosis induced by FLIP silencing.
    Wilson TR, Redmond KM, McLaughlin KM, Crawford N, Gately K, O'Byrne K, Le-Clorrenec C, Holohan C, Fennell DA, Johnston PG, Longley DB.
    Cell Death Differ; 2009 Oct 07; 16(10):1352-61. PubMed ID: 19543235
    [Abstract] [Full Text] [Related]

  • 16. The eIF4E/eIF4G interaction inhibitor 4EGI-1 augments TRAIL-mediated apoptosis through c-FLIP Down-regulation and DR5 induction independent of inhibition of cap-dependent protein translation.
    Fan S, Li Y, Yue P, Khuri FR, Sun SY.
    Neoplasia; 2010 Apr 07; 12(4):346-56. PubMed ID: 20360945
    [Abstract] [Full Text] [Related]

  • 17. Kaempferol Sensitizes Human Ovarian Cancer Cells-OVCAR-3 and SKOV-3 to Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL)-Induced Apoptosis via JNK/ERK-CHOP Pathway and Up-Regulation of Death Receptors 4 and 5.
    Zhao Y, Tian B, Wang Y, Ding H.
    Med Sci Monit; 2017 Oct 26; 23():5096-5105. PubMed ID: 29070784
    [Abstract] [Full Text] [Related]

  • 18. Down-regulation of Cbl-b by bufalin results in up-regulation of DR4/DR5 and sensitization of TRAIL-induced apoptosis in breast cancer cells.
    Yan S, Qu X, Xu C, Zhu Z, Zhang L, Xu L, Song N, Teng Y, Liu Y.
    J Cancer Res Clin Oncol; 2012 Aug 26; 138(8):1279-89. PubMed ID: 22447040
    [Abstract] [Full Text] [Related]

  • 19. DR5-mediated DISC controls caspase-8 cleavage and initiation of apoptosis in human glioblastomas.
    Bellail AC, Tse MC, Song JH, Phuphanich S, Olson JJ, Sun SY, Hao C.
    J Cell Mol Med; 2010 Jun 26; 14(6A):1303-17. PubMed ID: 19432816
    [Abstract] [Full Text] [Related]

  • 20. Downregulation of active caspase 8 as a mechanism of acquired TRAIL resistance in mismatch repair-proficient colon carcinoma cell lines.
    Van Geelen CM, Pennarun B, Ek WB, Le PT, Spierings DC, De Vries EG, De Jong S.
    Int J Oncol; 2010 Oct 26; 37(4):1031-41. PubMed ID: 20811726
    [Abstract] [Full Text] [Related]

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