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Journal Abstract Search

344 related items for PubMed ID: 22949330

  • 1. Semi-synthesis and biological evaluation of 1,2,3-triazole-based podophyllotoxin congeners as potent antitumor agents inducing apoptosis in HepG2 cells.
    Chen J, Ma L, Zhang R, Tang J, Lai H, Wang J, Wang G, Xu Q, Chen T, Peng F, Qiu J, Liang X, Cao D, Ran Y, Peng A, Wei Y, Chen L.
    Arch Pharm (Weinheim); 2012 Dec; 345(12):945-56. PubMed ID: 22949330
    [Abstract] [Full Text] [Related]

  • 2. Design, synthesis, and biological testing of 4beta-[(4-substituted)-1,2,3-triazol-1-yl]podophyllotoxin analogues as antitumor agents.
    Reddy PB, Paul DV, Agrawal SK, Saxena AK, Kumar HM, Qazi GN.
    Arch Pharm (Weinheim); 2008 Feb; 341(2):126-31. PubMed ID: 18214838
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and cytotoxic activity on human cancer cells of carbamate derivatives of 4β-(1,2,3-triazol-1-yl)podophyllotoxin.
    Liu JF, Sang CY, Xu XH, Zhang LL, Yang X, Hui L, Zhang JB, Chen SW.
    Eur J Med Chem; 2013 Jun; 64():621-8. PubMed ID: 23711769
    [Abstract] [Full Text] [Related]

  • 4. 4β-[(4-Alkyl)-1,2,3-triazol-1-yl] podophyllotoxins as anticancer compounds: design, synthesis and biological evaluation.
    Reddy DM, Srinivas J, Chashoo G, Saxena AK, Sampath Kumar HM.
    Eur J Med Chem; 2011 Jun; 46(6):1983-91. PubMed ID: 21477899
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and biological evaluation of 4beta-[(4-substituted)-1,2,3-triazol-1-yl]podophyllotoxins as potential anticancer agents.
    Reddy PB, Agrawal SK, Singh S, Bhat BA, Saxena AK, Kumar HM, Qazi GN.
    Chem Biodivers; 2008 Sep; 5(9):1792-802. PubMed ID: 18816530
    [Abstract] [Full Text] [Related]

  • 6. 4β-amidotriazole linked podophyllotoxin congeners: DNA topoisomerase-IIα inhibition and potential anticancer agents for prostate cancer.
    Reddy VG, Bonam SR, Reddy TS, Akunuri R, Naidu VGM, Nayak VL, Bhargava SK, Kumar HMS, Srihari P, Kamal A.
    Eur J Med Chem; 2018 Jan 20; 144():595-611. PubMed ID: 29289884
    [Abstract] [Full Text] [Related]

  • 7. A convergent synthesis of alkyne-azide cycloaddition derivatives of 4-α,β-2-propyne podophyllotoxin depicting potent cytotoxic activity.
    Zilla MK, Nayak D, Vishwakarma RA, Sharma PR, Goswami A, Ali A.
    Eur J Med Chem; 2014 Apr 22; 77():47-55. PubMed ID: 24607588
    [Abstract] [Full Text] [Related]

  • 8. Synthesis and cytotoxicity evaluation of novel podophyllotoxin derivatives.
    Chengniu W, Zhonghua W, Yu Z, Chunyan N, Xiaodong Z, Li Z.
    Arch Pharm (Weinheim); 2011 Nov 22; 344(11):735-40. PubMed ID: 21887802
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and biological evaluation of new 4beta-anilino- and 4beta-imido-substituted podophyllotoxin congeners.
    Kamal A, Gayatri NL, Reddy DR, Mohan Reddy PS, Arifuddin M, Dastidar SG, Kondapi AK, Rajkumar M.
    Bioorg Med Chem; 2005 Nov 15; 13(22):6218-25. PubMed ID: 16061385
    [Abstract] [Full Text] [Related]

  • 10. Studies on novel 4beta-[(4-substituted)-1,2,3-triazol-1-yl] podophyllotoxins as potential anticancer agents.
    Bhat BA, Reddy PB, Agrawal SK, Saxena AK, Kumar HM, Qazi GN.
    Eur J Med Chem; 2008 Oct 15; 43(10):2067-72. PubMed ID: 17988764
    [Abstract] [Full Text] [Related]

  • 11. Synthesis and biological evaluation of novel podophyllotoxin analogs as antitumor agents.
    Zhang ZH, Zhang LM, Luo G, Zhang S, Chen H, Zhou J.
    J Asian Nat Prod Res; 2014 Oct 15; 16(5):527-34. PubMed ID: 24824554
    [Abstract] [Full Text] [Related]

  • 12. Synthesis and biological evaluation of 4β-acrylamidopodophyllotoxin congeners as DNA damaging agents.
    Kamal A, Suresh P, Janaki Ramaiah M, Mallareddy A, Kumar BA, Raju P, Vinay Gopal J, Pushpavalli SN, Lavanya A, Sarma P, Pal-Bhadra M.
    Bioorg Med Chem; 2011 Aug 01; 19(15):4589-600. PubMed ID: 21737288
    [Abstract] [Full Text] [Related]

  • 13. Design, synthesis and molecular docking studies of novel N-benzenesulfonyl-1,2,3,4-tetrahydroisoquinoline-based triazoles with potential anticancer activity.
    Pingaew R, Mandi P, Nantasenamat C, Prachayasittikul S, Ruchirawat S, Prachayasittikul V.
    Eur J Med Chem; 2014 Jun 23; 81():192-203. PubMed ID: 24836071
    [Abstract] [Full Text] [Related]

  • 14. A rational design strategy of the novel topoisomerase II inhibitors for the synthesis of the 4-O-(2-pyrazinecarboxylic)-4'-demethylepipodophyllotoxin with antitumor activity by diminishing the relaxation reaction of topoisomerase II-DNA decatenation.
    Zhao W, Chen L, Li HM, Wang DJ, Li DS, Chen T, Yuan ZP, Tang YJ.
    Bioorg Med Chem; 2014 Jun 01; 22(11):2998-3007. PubMed ID: 24775914
    [Abstract] [Full Text] [Related]

  • 15. One-pot synthesis of podophyllotoxin-thiourea congeners by employing NH₂SO₃H/NaI: Anticancer activity, DNA topoisomerase-II inhibition, and apoptosis inducing agents.
    Shankaraiah N, Kumar NP, Amula SB, Nekkanti S, Jeengar MK, Naidu VG, Reddy TS, Kamal A.
    Bioorg Med Chem Lett; 2015 Oct 01; 25(19):4239-44. PubMed ID: 26292628
    [Abstract] [Full Text] [Related]

  • 16. Synthesis of 4β-triazole-podophyllotoxin derivatives by azide-alkyne cycloaddition and biological evaluation as potential antitumor agents.
    Chen H, Zuo S, Wang X, Tang X, Zhao M, Lu Y, Chen L, Liu J, Liu Y, Liu D, Zhang S, Li T.
    Eur J Med Chem; 2011 Sep 01; 46(9):4709-14. PubMed ID: 21821321
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and biological evaluation of 4β-sulphonamido and 4β-[(4'-sulphonamido)benzamide]podophyllotoxins as DNA topoisomerase-IIα and apoptosis inducing agents.
    Kamal A, Suresh P, Ramaiah MJ, Mallareddy A, Imthiajali S, Pushpavalli SN, Lavanya A, Pal-Bhadra M.
    Bioorg Med Chem; 2012 Mar 15; 20(6):2054-66. PubMed ID: 22364746
    [Abstract] [Full Text] [Related]

  • 18. Synthesis and biological evaluation of a series of podophyllotoxins derivatives as a class of potent antitubulin agents.
    Liu Y, Wei D, Zhao Y, Cheng W, Lu Y, Ma Y, Li X, Han C, Wei Y, Cao H, Zhao C.
    Bioorg Med Chem; 2012 Nov 01; 20(21):6285-95. PubMed ID: 23022053
    [Abstract] [Full Text] [Related]

  • 19. Synthesis of 4β-N-polyaromatic substituted podophyllotoxins: DNA topoisomerase inhibition, anticancer and apoptosis-inducing activities.
    Kamal A, Kumar BA, Suresh P, Agrawal SK, Chashoo G, Singh SK, Saxena AK.
    Bioorg Med Chem; 2010 Dec 15; 18(24):8493-500. PubMed ID: 21074444
    [Abstract] [Full Text] [Related]

  • 20. 4β-[4'-(1-(Aryl)ureido)benzamide]podophyllotoxins as DNA topoisomerase I and IIα inhibitors and apoptosis inducing agents.
    Kamal A, Suresh P, Ramaiah MJ, Srinivasa Reddy T, Kapavarapu RK, Rao BN, Imthiajali S, Lakshminarayan Reddy T, Pushpavalli SN, Shankaraiah N, Pal-Bhadra M.
    Bioorg Med Chem; 2013 Sep 01; 21(17):5198-208. PubMed ID: 23849207
    [Abstract] [Full Text] [Related]

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