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237 related items for PubMed ID: 22960596

  • 1. Simvastatin inhibition of mevalonate pathway induces apoptosis in human breast cancer cells via activation of JNK/CHOP/DR5 signaling pathway.
    Gopalan A, Yu W, Sanders BG, Kline K.
    Cancer Lett; 2013 Feb 01; 329(1):9-16. PubMed ID: 22960596
    [Abstract] [Full Text] [Related]

  • 2. Involvement of de novo ceramide synthesis in gamma-tocopherol and gamma-tocotrienol-induced apoptosis in human breast cancer cells.
    Gopalan A, Yu W, Jiang Q, Jang Y, Sanders BG, Kline K.
    Mol Nutr Food Res; 2012 Dec 01; 56(12):1803-11. PubMed ID: 23065795
    [Abstract] [Full Text] [Related]

  • 3. Tocotrienols induce apoptosis in breast cancer cell lines via an endoplasmic reticulum stress-dependent increase in extrinsic death receptor signaling.
    Park SK, Sanders BG, Kline K.
    Breast Cancer Res Treat; 2010 Nov 01; 124(2):361-75. PubMed ID: 20157774
    [Abstract] [Full Text] [Related]

  • 4. Arsenic trioxide sensitizes human glioma cells, but not normal astrocytes, to TRAIL-induced apoptosis via CCAAT/enhancer-binding protein homologous protein-dependent DR5 up-regulation.
    Kim EH, Yoon MJ, Kim SU, Kwon TK, Sohn S, Choi KS.
    Cancer Res; 2008 Jan 01; 68(1):266-75. PubMed ID: 18172319
    [Abstract] [Full Text] [Related]

  • 5. Tanshinone IIA Facilitates TRAIL Sensitization by Up-regulating DR5 through the ROS-JNK-CHOP Signaling Axis in Human Ovarian Carcinoma Cell Lines.
    Chang CC, Kuan CP, Lin JY, Lai JS, Ho TF.
    Chem Res Toxicol; 2015 Aug 17; 28(8):1574-83. PubMed ID: 26203587
    [Abstract] [Full Text] [Related]

  • 6. Upregulation of DR5 by proteasome inhibitors potently sensitizes glioma cells to TRAIL-induced apoptosis.
    Hetschko H, Voss V, Seifert V, Prehn JH, Kögel D.
    FEBS J; 2008 Apr 17; 275(8):1925-36. PubMed ID: 18341587
    [Abstract] [Full Text] [Related]

  • 7. Phosphorylation of eIF2α attenuates statin-induced apoptosis by inhibiting the stabilization and translocation of p53 to the mitochondria.
    Lee SK, Kim YS.
    Int J Oncol; 2013 Mar 17; 42(3):810-6. PubMed ID: 23354132
    [Abstract] [Full Text] [Related]

  • 8. Simvastatin inhibits C-reactive protein-induced pro-inflammatory changes in endothelial cells by decreasing mevalonate pathway products.
    Liang YJ, Shyu KG, Wang BW, Lai LP.
    Cardiology; 2008 Mar 17; 110(3):182-90. PubMed ID: 18057884
    [Abstract] [Full Text] [Related]

  • 9. CAAT/enhancer binding protein homologous protein-dependent death receptor 5 induction is a major component of SHetA2-induced apoptosis in lung cancer cells.
    Lin YD, Chen S, Yue P, Zou W, Benbrook DM, Liu S, Le TC, Berlin KD, Khuri FR, Sun SY.
    Cancer Res; 2008 Jul 01; 68(13):5335-44. PubMed ID: 18593935
    [Abstract] [Full Text] [Related]

  • 10. Role of endoplasmic reticulum stress in alpha-TEA mediated TRAIL/DR5 death receptor dependent apoptosis.
    Tiwary R, Yu W, Li J, Park SK, Sanders BG, Kline K.
    PLoS One; 2010 Jul 29; 5(7):e11865. PubMed ID: 20686688
    [Abstract] [Full Text] [Related]

  • 11. Distinct roles of different forms of vitamin E in DHA-induced apoptosis in triple-negative breast cancer cells.
    Xiong A, Yu W, Tiwary R, Sanders BG, Kline K.
    Mol Nutr Food Res; 2012 Jun 29; 56(6):923-34. PubMed ID: 22707267
    [Abstract] [Full Text] [Related]

  • 12. Verrucarin A sensitizes TRAIL-induced apoptosis via the upregulation of DR5 in an eIF2α/CHOP-dependent manner.
    Moon DO, Asami Y, Long H, Jang JH, Bae EY, Kim BY, Choi YH, Kang CH, Ahn JS, Kim GY.
    Toxicol In Vitro; 2013 Feb 29; 27(1):257-63. PubMed ID: 22982206
    [Abstract] [Full Text] [Related]

  • 13. HMG-CoA reductase inhibitor simvastatin overcomes bortezomib-induced apoptosis resistance by disrupting a geranylgeranyl pyrophosphate-dependent survival pathway.
    Fuchs D, Berges C, Opelz G, Daniel V, Naujokat C.
    Biochem Biophys Res Commun; 2008 Sep 19; 374(2):309-14. PubMed ID: 18625202
    [Abstract] [Full Text] [Related]

  • 14. CCAAT/enhancer binding protein homologous protein-dependent death receptor 5 induction and ubiquitin/proteasome-mediated cellular FLICE-inhibitory protein down-regulation contribute to enhancement of tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by dimethyl-celecoxib in human non small-cell lung cancer cells.
    Chen S, Liu X, Yue P, Schönthal AH, Khuri FR, Sun SY.
    Mol Pharmacol; 2007 Nov 19; 72(5):1269-79. PubMed ID: 17684158
    [Abstract] [Full Text] [Related]

  • 15. Rottlerin induces apoptosis via death receptor 5 (DR5) upregulation through CHOP-dependent and PKC delta-independent mechanism in human malignant tumor cells.
    Lim JH, Park JW, Choi KS, Park YB, Kwon TK.
    Carcinogenesis; 2009 May 19; 30(5):729-36. PubMed ID: 19037087
    [Abstract] [Full Text] [Related]

  • 16. Licochalcone D exhibits cytotoxicity in breast cancer cells and enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis through upregulation of death receptor 5.
    Zhang Y, Wang L, Dong C, Zhuang Y, Hao G, Wang F.
    J Biochem Mol Toxicol; 2024 Jul 19; 38(7):e23757. PubMed ID: 38937960
    [Abstract] [Full Text] [Related]

  • 17. Simvastatin reduces lipoprotein-associated phospholipase A2 in lipopolysaccharide-stimulated human monocyte-derived macrophages through inhibition of the mevalonate-geranylgeranyl pyrophosphate-RhoA-p38 mitogen-activated protein kinase pathway.
    Song JX, Ren JY, Chen H.
    J Cardiovasc Pharmacol; 2011 Feb 19; 57(2):213-22. PubMed ID: 21052011
    [Abstract] [Full Text] [Related]

  • 18. Anti-gout agent allopurinol exerts cytotoxicity to human hormone-refractory prostate cancer cells in combination with tumor necrosis factor-related apoptosis-inducing ligand.
    Yasuda T, Yoshida T, Goda AE, Horinaka M, Yano K, Shiraishi T, Wakada M, Mizutani Y, Miki T, Sakai T.
    Mol Cancer Res; 2008 Dec 19; 6(12):1852-60. PubMed ID: 19074830
    [Abstract] [Full Text] [Related]

  • 19. Baicalein overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance via two different cell-specific pathways in cancer cells but not in normal cells.
    Taniguchi H, Yoshida T, Horinaka M, Yasuda T, Goda AE, Konishi M, Wakada M, Kataoka K, Yoshikawa T, Sakai T.
    Cancer Res; 2008 Nov 01; 68(21):8918-27. PubMed ID: 18974136
    [Abstract] [Full Text] [Related]

  • 20. Simvastatin antagonizes tumor necrosis factor-alpha inhibition of bone morphogenetic proteins-2-induced osteoblast differentiation by regulating Smad signaling and Ras/Rho-mitogen-activated protein kinase pathway.
    Yamashita M, Otsuka F, Mukai T, Otani H, Inagaki K, Miyoshi T, Goto J, Yamamura M, Makino H.
    J Endocrinol; 2008 Mar 01; 196(3):601-13. PubMed ID: 18310456
    [Abstract] [Full Text] [Related]

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