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Journal Abstract Search

422 related items for PubMed ID: 22961653

  • 1. Intrahepatic cholestasis of pregnancy levels of sulfated progesterone metabolites inhibit farnesoid X receptor resulting in a cholestatic phenotype.
    Abu-Hayyeh S, Papacleovoulou G, Lövgren-Sandblom A, Tahir M, Oduwole O, Jamaludin NA, Ravat S, Nikolova V, Chambers J, Selden C, Rees M, Marschall HU, Parker MG, Williamson C.
    Hepatology; 2013 Feb; 57(2):716-26. PubMed ID: 22961653
    [Abstract] [Full Text] [Related]

  • 2. Progesterone metabolites as farnesoid X receptor inhibitors.
    Abu-Hayyeh S, Williamson C.
    Dig Dis; 2015 Feb; 33(3):300-6. PubMed ID: 26045261
    [Abstract] [Full Text] [Related]

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  • 4. Promoter DNA methylation of farnesoid X receptor and pregnane X receptor modulates the intrahepatic cholestasis of pregnancy phenotype.
    Cabrerizo R, Castaño GO, Burgueño AL, Fernández Gianotti T, Gonzalez Lopez Ledesma MM, Flichman D, Pirola CJ, Sookoian S.
    PLoS One; 2014 Feb; 9(1):e87697. PubMed ID: 24498169
    [Abstract] [Full Text] [Related]

  • 5. Effect of maternal cholestasis on TGR5 expression in human and rat placenta at term.
    Keitel V, Spomer L, Marin JJ, Williamson C, Geenes V, Kubitz R, Häussinger D, Macias RI.
    Placenta; 2013 Sep; 34(9):810-6. PubMed ID: 23849932
    [Abstract] [Full Text] [Related]

  • 6. Functional variants of the central bile acid sensor FXR identified in intrahepatic cholestasis of pregnancy.
    Van Mil SW, Milona A, Dixon PH, Mullenbach R, Geenes VL, Chambers J, Shevchuk V, Moore GE, Lammert F, Glantz AG, Mattsson LA, Whittaker J, Parker MG, White R, Williamson C.
    Gastroenterology; 2007 Aug; 133(2):507-16. PubMed ID: 17681172
    [Abstract] [Full Text] [Related]

  • 7. Maternal and Fetal Bile Acid Homeostasis Regulated by Sulfated Progesterone Metabolites through FXR Signaling Pathway in a Pregnant Sow Model.
    Wang P, Yuan P, Lin S, Zhong H, Zhang X, Zhuo Y, Li J, Che L, Feng B, Lin Y, Xu S, Wu D, Burrin DG, Fang Z.
    Int J Mol Sci; 2022 Jun 10; 23(12):. PubMed ID: 35742938
    [Abstract] [Full Text] [Related]

  • 8. Obeticholic acid improves fetal bile acid profile in a mouse model of gestational hypercholanemia.
    Pataia V, McIlvride S, Papacleovoulou G, Ovadia C, McDonald JAK, Wahlström A, Jansen E, Adorini L, Shapiro D, Marchesi JR, Marschall HU, Williamson C.
    Am J Physiol Gastrointest Liver Physiol; 2020 Aug 01; 319(2):G197-G211. PubMed ID: 32597707
    [Abstract] [Full Text] [Related]

  • 9. Targeting FXR in Cholestasis.
    Keitel V, Dröge C, Häussinger D.
    Handb Exp Pharmacol; 2019 Aug 01; 256():299-324. PubMed ID: 31201556
    [Abstract] [Full Text] [Related]

  • 10. Agonist of farnesoid X receptor protects against bile acid induced damage and oxidative stress in mouse placenta--a study on maternal cholestasis model.
    Wu WB, Xu YY, Cheng WW, Wang YX, Liu Y, Huang D, Zhang HJ.
    Placenta; 2015 May 01; 36(5):545-51. PubMed ID: 25747729
    [Abstract] [Full Text] [Related]

  • 11. Bile acids and progesterone metabolites in intrahepatic cholestasis of pregnancy.
    Reyes H, Sjövall J.
    Ann Med; 2000 Mar 01; 32(2):94-106. PubMed ID: 10766400
    [Abstract] [Full Text] [Related]

  • 12. Inhibition of Na+-taurocholate Co-transporting polypeptide-mediated bile acid transport by cholestatic sulfated progesterone metabolites.
    Abu-Hayyeh S, Martinez-Becerra P, Sheikh Abdul Kadir SH, Selden C, Romero MR, Rees M, Marschall HU, Marin JJ, Williamson C.
    J Biol Chem; 2010 May 28; 285(22):16504-12. PubMed ID: 20177056
    [Abstract] [Full Text] [Related]

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  • 14. Yinchen decoction protects against cholic acid diet-induced cholestatic liver injury in mice through liver and ileal FXR signaling.
    Song G, Zou B, Zhao J, Weng F, Li Y, Xu X, Zhang S, Yan D, Jin J, Sun X, Liu C, Qiu F.
    J Ethnopharmacol; 2023 Sep 15; 313():116560. PubMed ID: 37149065
    [Abstract] [Full Text] [Related]

  • 15.
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  • 16. Potential role of trans-inhibition of the bile salt export pump by progesterone metabolites in the etiopathogenesis of intrahepatic cholestasis of pregnancy.
    Vallejo M, Briz O, Serrano MA, Monte MJ, Marin JJ.
    J Hepatol; 2006 Jun 15; 44(6):1150-7. PubMed ID: 16458994
    [Abstract] [Full Text] [Related]

  • 17. Effects of ursodeoxycholic acid on conjugated bile acids and progesterone metabolites in serum and urine of patients with intrahepatic cholestasis of pregnancy.
    Meng LJ, Reyes H, Palma J, Hernandez I, Ribalta J, Sjövall J.
    J Hepatol; 1997 Dec 15; 27(6):1029-40. PubMed ID: 9453429
    [Abstract] [Full Text] [Related]

  • 18. Alisol B 23-acetate protects against ANIT-induced hepatotoxity and cholestasis, due to FXR-mediated regulation of transporters and enzymes involved in bile acid homeostasis.
    Meng Q, Chen XL, Wang CY, Liu Q, Sun HJ, Sun PY, Huo XK, Liu ZH, Yao JH, Liu KX.
    Toxicol Appl Pharmacol; 2015 Mar 15; 283(3):178-86. PubMed ID: 25655198
    [Abstract] [Full Text] [Related]

  • 19. Profiles of bile acids and progesterone metabolites in the urine and serum of women with intrahepatic cholestasis of pregnancy.
    Meng LJ, Reyes H, Palma J, Hernandez I, Ribalta J, Sjövall J.
    J Hepatol; 1997 Aug 15; 27(2):346-57. PubMed ID: 9288610
    [Abstract] [Full Text] [Related]

  • 20. Intrahepatic Cholestasis of Pregnancy Increases Inflammatory Susceptibility in Neonatal Offspring by Modulating Gut Microbiota.
    Lin QX, Huang WW, Shen W, Deng XS, Tang ZY, Chen ZH, Zhao W, Fan HY.
    Front Immunol; 2022 Aug 15; 13():889646. PubMed ID: 35769469
    [Abstract] [Full Text] [Related]

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