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Journal Abstract Search


212 related items for PubMed ID: 2296310

  • 1. A transgenic mouse model of sickle cell disorder.
    Greaves DR, Fraser P, Vidal MA, Hedges MJ, Ropers D, Luzzatto L, Grosveld F.
    Nature; 1990 Jan 11; 343(6254):183-5. PubMed ID: 2296310
    [Abstract] [Full Text] [Related]

  • 2. Correction of sickle cell disease in transgenic mouse models by gene therapy.
    Pawliuk R, Westerman KA, Fabry ME, Payen E, Tighe R, Bouhassira EE, Acharya SA, Ellis J, London IM, Eaves CJ, Humphries RK, Beuzard Y, Nagel RL, Leboulch P.
    Science; 2001 Dec 14; 294(5550):2368-71. PubMed ID: 11743206
    [Abstract] [Full Text] [Related]

  • 3. High oxygen environment during pregnancy rescues sickle cell anemia mice from prenatal death.
    Ye L, Chang JC, Lu R, Kan YW.
    Blood Cells Mol Dis; 2008 Dec 14; 41(1):67-72. PubMed ID: 18207438
    [Abstract] [Full Text] [Related]

  • 4. Overview of pathophysiology and rationale for treatment of sickle cell anemia.
    Rodgers GP.
    Semin Hematol; 1997 Jul 14; 34(3 Suppl 3):2-7. PubMed ID: 9317195
    [Abstract] [Full Text] [Related]

  • 5. Mouse models of sickle cell disease.
    Beuzard Y.
    Transfus Clin Biol; 2008 Jul 14; 15(1-2):7-11. PubMed ID: 18502677
    [Abstract] [Full Text] [Related]

  • 6. Anti-beta s-ribozyme reduces beta s mRNA levels in transgenic mice: potential application to the gene therapy of sickle cell anemia.
    Alami R, Gilman JG, Feng YQ, Marmorato A, Rochlin I, Suzuka SM, Fabry ME, Nagel RL, Bouhassira EE.
    Blood Cells Mol Dis; 1999 Apr 14; 25(2):110-9. PubMed ID: 10389593
    [Abstract] [Full Text] [Related]

  • 7. Adeno-associated virus 2-mediated transduction and erythroid lineage-restricted long-term expression of the human beta-globin gene in hematopoietic cells from homozygous beta-thalassemic mice.
    Tan M, Qing K, Zhou S, Yoder MC, Srivastava A.
    Mol Ther; 2001 Jun 14; 3(6):940-6. PubMed ID: 11407908
    [Abstract] [Full Text] [Related]

  • 8. [Molecular and cellular pathophysiology of sickle cell anemia].
    Labie D, Elion J.
    Pathol Biol (Paris); 1999 Jan 14; 47(1):7-12. PubMed ID: 10081773
    [Abstract] [Full Text] [Related]

  • 9. Genetic correction of sickle cell disease: insights using transgenic mouse models.
    Blouin MJ, Beauchemin H, Wright A, De Paepe M, Sorette M, Bleau AM, Nakamoto B, Ou CN, Stamatoyannopoulos G, Trudel M.
    Nat Med; 2000 Feb 14; 6(2):177-82. PubMed ID: 10655106
    [Abstract] [Full Text] [Related]

  • 10. A novel transgenic mouse model produced from lentiviral germline integration for the study of beta-thalassemia gene therapy.
    Li W, Xie S, Guo X, Gong X, Wang S, Lin D, Zhang J, Ren Z, Huang S, Zeng F, Zeng Y.
    Haematologica; 2008 Mar 14; 93(3):356-62. PubMed ID: 18268280
    [Abstract] [Full Text] [Related]

  • 11. Beta globin gene inhibition by antisense RNA transcripts.
    Xu L, Ferry AE, Monteiro C, Pace BS.
    Gene Ther; 2000 Mar 14; 7(5):438-44. PubMed ID: 10694826
    [Abstract] [Full Text] [Related]

  • 12. Expression of an anti-sickling beta-globin in human erythroblasts derived from retrovirally transduced primitive normal and sickle cell disease hematopoietic cells.
    Oh IH, Fabry ME, Humphries RK, Pawliuk R, Leboulch P, Hoffman R, Nagel RL, Eaves C.
    Exp Hematol; 2004 May 14; 32(5):461-9. PubMed ID: 15145214
    [Abstract] [Full Text] [Related]

  • 13. Monovalent cation changes in sickle erythrocytes: a direct reflection of alpha-globin gene number.
    Embury SH, Backer K, Glader BE.
    J Lab Clin Med; 1985 Jul 14; 106(1):75-9. PubMed ID: 4009025
    [Abstract] [Full Text] [Related]

  • 14. Foetal haemoglobin levels in sickle cell anaemia in Nigerians.
    Falusi AG, Esan GJ.
    Afr J Med Med Sci; 1989 Jun 14; 18(2):145-9. PubMed ID: 2474239
    [Abstract] [Full Text] [Related]

  • 15. Sickling of nucleated erythroid precursors from patients with sickle cell anemia.
    Hasegawa S, Rodgers GP, Dwyer N, Noguchi CT, Blanchette-Mackie EJ, Uyesaka N, Schechter AN, Fibach E.
    Exp Hematol; 1998 Apr 14; 26(4):314-9. PubMed ID: 9546314
    [Abstract] [Full Text] [Related]

  • 16. Raised Hb F levels in sickle cell disease are caused by a determinant linked to the beta globin gene cluster.
    Kulozik AE, Thein SL, Kar BC, Wainscoat JS, Serjeant GR, Weatherall DJ.
    Prog Clin Biol Res; 1987 Apr 14; 251():427-39. PubMed ID: 2448811
    [Abstract] [Full Text] [Related]

  • 17. Pathophysiology and therapy for haemoglobinopathies. Part I: sickle cell disease.
    Madigan C, Malik P.
    Expert Rev Mol Med; 2006 Apr 28; 8(9):1-23. PubMed ID: 16690007
    [Abstract] [Full Text] [Related]

  • 18. Therapeutic haemoglobin synthesis in beta-thalassaemic mice expressing lentivirus-encoded human beta-globin.
    May C, Rivella S, Callegari J, Heller G, Gaensler KM, Luzzatto L, Sadelain M.
    Nature; 2000 Jul 06; 406(6791):82-6. PubMed ID: 10894546
    [Abstract] [Full Text] [Related]

  • 19. Sickle-cell haemoglobin polymerization: is it the primary pathogenic event of sickle-cell anaemia?
    Vekilov PG.
    Br J Haematol; 2007 Oct 06; 139(2):173-84. PubMed ID: 17897293
    [Abstract] [Full Text] [Related]

  • 20. Transgenic knockout mice exclusively expressing human hemoglobin S after transfer of a 240-kb betas-globin yeast artificial chromosome: A mouse model of sickle cell anemia.
    Chang JC, Lu R, Lin C, Xu SM, Kan YW, Porcu S, Carlson E, Kitamura M, Yang S, Flebbe-Rehwaldt L, Gaensler KM.
    Proc Natl Acad Sci U S A; 1998 Dec 08; 95(25):14886-90. PubMed ID: 9843985
    [Abstract] [Full Text] [Related]


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