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Journal Abstract Search

479 related items for PubMed ID: 22964643

  • 1. RAD52 inactivation is synthetically lethal with deficiencies in BRCA1 and PALB2 in addition to BRCA2 through RAD51-mediated homologous recombination.
    Lok BH, Carley AC, Tchang B, Powell SN.
    Oncogene; 2013 Jul 25; 32(30):3552-8. PubMed ID: 22964643
    [Abstract] [Full Text] [Related]

  • 2. Pan-cancer analysis of co-occurring mutations in RAD52 and the BRCA1-BRCA2-PALB2 axis in human cancers.
    Hamid AB, Frank LE, Bouley RA, Petreaca RC.
    PLoS One; 2022 Jul 25; 17(9):e0273736. PubMed ID: 36107942
    [Abstract] [Full Text] [Related]

  • 3. Rad52 inactivation is synthetically lethal with BRCA2 deficiency.
    Feng Z, Scott SP, Bussen W, Sharma GG, Guo G, Pandita TK, Powell SN.
    Proc Natl Acad Sci U S A; 2011 Jan 11; 108(2):686-91. PubMed ID: 21148102
    [Abstract] [Full Text] [Related]

  • 4. Palb2 synergizes with Trp53 to suppress mammary tumor formation in a model of inherited breast cancer.
    Bowman-Colin C, Xia B, Bunting S, Klijn C, Drost R, Bouwman P, Fineman L, Chen X, Culhane AC, Cai H, Rodig SJ, Bronson RT, Jonkers J, Nussenzweig A, Kanellopoulou C, Livingston DM.
    Proc Natl Acad Sci U S A; 2013 May 21; 110(21):8632-7. PubMed ID: 23657012
    [Abstract] [Full Text] [Related]

  • 5. Molecular pathways: understanding the role of Rad52 in homologous recombination for therapeutic advancement.
    Lok BH, Powell SN.
    Clin Cancer Res; 2012 Dec 01; 18(23):6400-6. PubMed ID: 23071261
    [Abstract] [Full Text] [Related]

  • 6. PALB2 links BRCA1 and BRCA2 in the DNA-damage response.
    Zhang F, Ma J, Wu J, Ye L, Cai H, Xia B, Yu X.
    Curr Biol; 2009 Mar 24; 19(6):524-9. PubMed ID: 19268590
    [Abstract] [Full Text] [Related]

  • 7. The endonuclease EEPD1 mediates synthetic lethality in RAD52-depleted BRCA1 mutant breast cancer cells.
    Hromas R, Kim HS, Sidhu G, Williamson E, Jaiswal A, Totterdale TA, Nole J, Lee SH, Nickoloff JA, Kong KY.
    Breast Cancer Res; 2017 Nov 16; 19(1):122. PubMed ID: 29145865
    [Abstract] [Full Text] [Related]

  • 8. BRCA1-Dependent and Independent Recruitment of PALB2-BRCA2-RAD51 in the DNA Damage Response and Cancer.
    Foo TK, Xia B.
    Cancer Res; 2022 Sep 16; 82(18):3191-3197. PubMed ID: 35819255
    [Abstract] [Full Text] [Related]

  • 9. Personalized synthetic lethality induced by targeting RAD52 in leukemias identified by gene mutation and expression profile.
    Cramer-Morales K, Nieborowska-Skorska M, Scheibner K, Padget M, Irvine DA, Sliwinski T, Haas K, Lee J, Geng H, Roy D, Slupianek A, Rassool FV, Wasik MA, Childers W, Copland M, Müschen M, Civin CI, Skorski T.
    Blood; 2013 Aug 15; 122(7):1293-304. PubMed ID: 23836560
    [Abstract] [Full Text] [Related]

  • 10. Plasticity of BRCA2 function in homologous recombination: genetic interactions of the PALB2 and DNA binding domains.
    Siaud N, Barbera MA, Egashira A, Lam I, Christ N, Schlacher K, Xia B, Jasin M.
    PLoS Genet; 2011 Dec 15; 7(12):e1002409. PubMed ID: 22194698
    [Abstract] [Full Text] [Related]

  • 11. Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair.
    Park JY, Singh TR, Nassar N, Zhang F, Freund M, Hanenberg H, Meetei AR, Andreassen PR.
    Oncogene; 2014 Oct 02; 33(40):4803-12. PubMed ID: 24141787
    [Abstract] [Full Text] [Related]

  • 12. Requirement of heterogeneous nuclear ribonucleoprotein C for BRCA gene expression and homologous recombination.
    Anantha RW, Alcivar AL, Ma J, Cai H, Simhadri S, Ule J, König J, Xia B.
    PLoS One; 2013 Oct 02; 8(4):e61368. PubMed ID: 23585894
    [Abstract] [Full Text] [Related]

  • 13. Replication Protein A Phosphorylation Facilitates RAD52-Dependent Homologous Recombination in BRCA-Deficient Cells.
    Carley AC, Jalan M, Subramanyam S, Roy R, Borgstahl GEO, Powell SN.
    Mol Cell Biol; 2022 Feb 17; 42(2):e0052421. PubMed ID: 34928169
    [Abstract] [Full Text] [Related]

  • 14. PALB2 is an integral component of the BRCA complex required for homologous recombination repair.
    Sy SM, Huen MS, Chen J.
    Proc Natl Acad Sci U S A; 2009 Apr 28; 106(17):7155-60. PubMed ID: 19369211
    [Abstract] [Full Text] [Related]

  • 15. PALB2 functionally connects the breast cancer susceptibility proteins BRCA1 and BRCA2.
    Zhang F, Fan Q, Ren K, Andreassen PR.
    Mol Cancer Res; 2009 Jul 28; 7(7):1110-8. PubMed ID: 19584259
    [Abstract] [Full Text] [Related]

  • 16. Selective killing of homologous recombination-deficient cancer cell lines by inhibitors of the RPA:RAD52 protein-protein interaction.
    Al-Mugotir M, Lovelace JJ, George J, Bessho M, Pal D, Struble L, Kolar C, Rana S, Natarajan A, Bessho T, Borgstahl GEO.
    PLoS One; 2021 Jul 28; 16(3):e0248941. PubMed ID: 33784323
    [Abstract] [Full Text] [Related]

  • 17. Methotrexate-mediated inhibition of RAD51 expression and homologous recombination in cancer cells.
    Du LQ, Du XQ, Bai JQ, Wang Y, Yang QS, Wang XC, Zhao P, Wang H, Liu Q, Fan FY.
    J Cancer Res Clin Oncol; 2012 May 28; 138(5):811-8. PubMed ID: 22274865
    [Abstract] [Full Text] [Related]

  • 18. Rad51 paralog complexes BCDX2 and CX3 act at different stages in the BRCA1-BRCA2-dependent homologous recombination pathway.
    Chun J, Buechelmaier ES, Powell SN.
    Mol Cell Biol; 2013 Jan 28; 33(2):387-95. PubMed ID: 23149936
    [Abstract] [Full Text] [Related]

  • 19. PALB2 regulates recombinational repair through chromatin association and oligomerization.
    Sy SM, Huen MS, Zhu Y, Chen J.
    J Biol Chem; 2009 Jul 03; 284(27):18302-10. PubMed ID: 19423707
    [Abstract] [Full Text] [Related]

  • 20. PALB2 self-interaction controls homologous recombination.
    Buisson R, Masson JY.
    Nucleic Acids Res; 2012 Nov 01; 40(20):10312-23. PubMed ID: 22941656
    [Abstract] [Full Text] [Related]

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