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Journal Abstract Search

248 related items for PubMed ID: 22966074

  • 1. The Wnt signaling pathway effector TCF7L2 controls gut and brain proglucagon gene expression and glucose homeostasis.
    Shao W, Wang D, Chiang YT, Ip W, Zhu L, Xu F, Columbus J, Belsham DD, Irwin DM, Zhang H, Wen X, Wang Q, Jin T.
    Diabetes; 2013 Mar; 62(3):789-800. PubMed ID: 22966074
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  • 2. P21-activated protein kinase 1 (Pak1) mediates the cross talk between insulin and β-catenin on proglucagon gene expression and its ablation affects glucose homeostasis in male C57BL/6 mice.
    Chiang YA, Shao W, Xu XX, Chernoff J, Jin T.
    Endocrinology; 2013 Jan; 154(1):77-88. PubMed ID: 23183186
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  • 3. The LIM homeodomain protein ISL1 mediates the function of TCF7L2 in pancreatic beta cells.
    Shao W, Szeto V, Song Z, Tian L, Feng ZP, Nostro MC, Jin T.
    J Mol Endocrinol; 2018 Jul; 61(1):1-12. PubMed ID: 29678908
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  • 4. The Wnt signaling pathway effector TCF7L2 is upregulated by insulin and represses hepatic gluconeogenesis.
    Ip W, Shao W, Chiang YT, Jin T.
    Am J Physiol Endocrinol Metab; 2012 Nov 01; 303(9):E1166-76. PubMed ID: 22967502
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  • 5. Insulin detemir enhances proglucagon gene expression in the intestinal L cells via stimulating β-catenin and CREB activities.
    Liu S, Liu R, Chiang YT, Song L, Li X, Jin T, Wang Q.
    Am J Physiol Endocrinol Metab; 2012 Sep 15; 303(6):E740-51. PubMed ID: 22811470
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  • 8. Intestine-selective reduction of Gcg expression reveals the importance of the distal gut for GLP-1 secretion.
    Panaro BL, Yusta B, Matthews D, Koehler JA, Song Y, Sandoval DA, Drucker DJ.
    Mol Metab; 2020 Jul 15; 37():100990. PubMed ID: 32278655
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  • 13. The Role of Pancreatic Preproglucagon in Glucose Homeostasis in Mice.
    Chambers AP, Sorrell JE, Haller A, Roelofs K, Hutch CR, Kim KS, Gutierrez-Aguilar R, Li B, Drucker DJ, D'Alessio DA, Seeley RJ, Sandoval DA.
    Cell Metab; 2017 Apr 04; 25(4):927-934.e3. PubMed ID: 28325479
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  • 14. The developmental Wnt signaling pathway effector β-catenin/TCF mediates hepatic functions of the sex hormone estradiol in regulating lipid metabolism.
    Tian L, Shao W, Ip W, Song Z, Badakhshi Y, Jin T.
    PLoS Biol; 2019 Oct 04; 17(10):e3000444. PubMed ID: 31589598
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  • 17. Pancreatic alpha cell-selective deletion of Tcf7l2 impairs glucagon secretion and counter-regulatory responses to hypoglycaemia in mice.
    da Silva Xavier G, Mondragon A, Mourougavelou V, Cruciani-Guglielmacci C, Denom J, Herrera PL, Magnan C, Rutter GA.
    Diabetologia; 2017 Jun 04; 60(6):1043-1050. PubMed ID: 28343277
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  • 18. Mechanisms underlying proglucagon gene expression.
    Jin T.
    J Endocrinol; 2008 Jul 04; 198(1):17-28. PubMed ID: 18577568
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  • 19. TCF7L2 in mouse pancreatic beta cells plays a crucial role in glucose homeostasis by regulating beta cell mass.
    Takamoto I, Kubota N, Nakaya K, Kumagai K, Hashimoto S, Kubota T, Inoue M, Kajiwara E, Katsuyama H, Obata A, Sakurai Y, Iwamoto M, Kitamura T, Ueki K, Kadowaki T.
    Diabetologia; 2014 Mar 04; 57(3):542-53. PubMed ID: 24317852
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  • 20. Selective disruption of Tcf7l2 in the pancreatic β cell impairs secretory function and lowers β cell mass.
    Mitchell RK, Mondragon A, Chen L, Mcginty JA, French PM, Ferrer J, Thorens B, Hodson DJ, Rutter GA, Da Silva Xavier G.
    Hum Mol Genet; 2015 Mar 01; 24(5):1390-9. PubMed ID: 25355422
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