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Journal Abstract Search

129 related items for PubMed ID: 22966891

  • 1. Association of DHODH haplotype variants and response to leflunomide treatment in rheumatoid arthritis.
    O'Doherty C, Schnabl M, Spargo L, Cleland LG, James M, Proudman SM, Wiese MD.
    Pharmacogenomics; 2012 Sep; 13(12):1427-34. PubMed ID: 22966891
    [Abstract] [Full Text] [Related]

  • 2. The effect of exon (19C>A) dihydroorotate dehydrogenase gene polymorphism on rheumatoid arthritis treatment with leflunomide.
    Pawlik A, Herczynska M, Kurzawski M, Safranow K, Dziedziejko V, Drozdzik M.
    Pharmacogenomics; 2009 Feb; 10(2):303-9. PubMed ID: 19207032
    [Abstract] [Full Text] [Related]

  • 3. Precision Medicine With Leflunomide: Consideration of the DHODH Haplotype and Plasma Teriflunomide Concentration and Modification of Outcomes in Patients With Rheumatoid Arthritis.
    Wiese MD, Hopkins AM, King C, Wechalekar MD, Lee A, Spargo L, Metcalf R, McWilliams L, Hill C, Cleland LG, Proudman SM.
    Arthritis Care Res (Hoboken); 2021 Jul; 73(7):983-989. PubMed ID: 32339392
    [Abstract] [Full Text] [Related]

  • 4. Dihydroorotate dehydrogenase polymorphism influences the toxicity of leflunomide treatment in patients with rheumatoid arthritis.
    Grabar PB, Rozman B, Logar D, Praprotnik S, Dolzan V.
    Ann Rheum Dis; 2009 Aug; 68(8):1367-8. PubMed ID: 19605743
    [No Abstract] [Full Text] [Related]

  • 5. Mechanism of action of leflunomide in rheumatoid arthritis.
    Fox RI.
    J Rheumatol Suppl; 1998 Jul; 53():20-6. PubMed ID: 9666414
    [Abstract] [Full Text] [Related]

  • 6. Leflunomide, a new disease-modifying drug for treating active rheumatoid arthritis in methotrexate-controlled phase II clinical trial.
    Bao C, Chen S, Gu Y, Lao Z, Ni L, Yu Q, Xu J, Li X, Liu J, Sun L, He P, Ma J, Xu S, Ding C.
    Chin Med J (Engl); 2003 Aug; 116(8):1228-34. PubMed ID: 12935395
    [Abstract] [Full Text] [Related]

  • 7. Validation of the associations between single nucleotide polymorphisms or haplotypes and responses to disease-modifying antirheumatic drugs in patients with rheumatoid arthritis: a proposal for prospective pharmacogenomic study in clinical practice.
    Taniguchi A, Urano W, Tanaka E, Furihata S, Kamitsuji S, Inoue E, Yamanaka M, Yamanaka H, Kamatani N.
    Pharmacogenet Genomics; 2007 Jun; 17(6):383-90. PubMed ID: 17502830
    [Abstract] [Full Text] [Related]

  • 8. Leflunomide in active rheumatoid arthritis: a prospective study in daily practice.
    Van Roon EN, Jansen TL, Mourad L, Houtman PM, Bruyn GA, Griep EN, Wilffert B, Tobi H, Brouwers JR.
    Br J Clin Pharmacol; 2004 Jun; 57(6):790-7. PubMed ID: 15151525
    [Abstract] [Full Text] [Related]

  • 9. Polymorphisms in cytochrome P450 2C19 enzyme and cessation of leflunomide in patients with rheumatoid arthritis.
    Wiese MD, Schnabl M, O'Doherty C, Spargo LD, Sorich MJ, Cleland LG, Proudman SM.
    Arthritis Res Ther; 2012 Jul 12; 14(4):R163. PubMed ID: 22784880
    [Abstract] [Full Text] [Related]

  • 10. Leflunomide in clinical practice.
    Pinto P, Dougados M.
    Acta Reumatol Port; 2006 Jul 12; 31(3):215-24. PubMed ID: 17094333
    [Abstract] [Full Text] [Related]

  • 11. Leflunomide in clinical practice. A retrospective observational study on use of leflunomide in New Zealand.
    Jagoda JS, Rajapakse CN.
    Int J Rheum Dis; 2011 Oct 12; 14(4):340-4. PubMed ID: 22004230
    [Abstract] [Full Text] [Related]

  • 12. The influence of previous and concomitant leflunomide on the efficacy and safety of infliximab therapy in patients with rheumatoid arthritis; a longitudinal observational study.
    Flendrie M, Creemers MC, Welsing PM, van Riel PL.
    Rheumatology (Oxford); 2005 Apr 12; 44(4):472-8. PubMed ID: 15598707
    [Abstract] [Full Text] [Related]

  • 13. Comparative effectiveness of tumour necrosis factor alpha inhibitors in combination with either methotrexate or leflunomide.
    Strangfeld A, Hierse F, Kekow J, von Hinueber U, Tony HP, Dockhorn R, Listing J, Zink A.
    Ann Rheum Dis; 2009 Dec 12; 68(12):1856-62. PubMed ID: 19126559
    [Abstract] [Full Text] [Related]

  • 14. Two-year, blinded, randomized, controlled trial of treatment of active rheumatoid arthritis with leflunomide compared with methotrexate. Utilization of Leflunomide in the Treatment of Rheumatoid Arthritis Trial Investigator Group.
    Cohen S, Cannon GW, Schiff M, Weaver A, Fox R, Olsen N, Furst D, Sharp J, Moreland L, Caldwell J, Kaine J, Strand V.
    Arthritis Rheum; 2001 Sep 12; 44(9):1984-92. PubMed ID: 11592358
    [Abstract] [Full Text] [Related]

  • 15. Leflunomide and rheumatoid arthritis: new preparation. Neither the safest nor the most effective slow-acting antirheumatic drug.
    Prescrire Int; 2001 Apr 12; 10(52):36-9. PubMed ID: 11718154
    [Abstract] [Full Text] [Related]

  • 16. Clinical experience with leflunomide in rheumatoid arthritis. Leflunomide Investigators' Group.
    Rozman B.
    J Rheumatol Suppl; 1998 Jul 12; 53():27-32. PubMed ID: 9666415
    [Abstract] [Full Text] [Related]

  • 17. The effect of ESR1 and ESR2 gene polymorphisms on the outcome of rheumatoid arthritis treatment with leflunomide.
    Dziedziejko V, Kurzawski M, Safranow K, Chlubek D, Pawlik A.
    Pharmacogenomics; 2011 Jan 12; 12(1):41-7. PubMed ID: 21174621
    [Abstract] [Full Text] [Related]

  • 18. Genetic polymorphisms in metabolic pathways of leflunomide in the treatment of rheumatoid arthritis.
    Soukup T, Dosedel M, Nekvindova J, Toms J, Vlcek J, Pavek P.
    Clin Exp Rheumatol; 2015 Jan 12; 33(3):426-32. PubMed ID: 25664505
    [Abstract] [Full Text] [Related]

  • 19. Leflunomide discontinuation in rheumatoid arthritis and influence of associated disease-modifying anti-rheumatic drugs: a survival analysis.
    Rodriguez-Rodriguez L, Jover-Jover JA, Fontsere O, Peña-Blanco RC, León L, Fernández-Gutierrez B, Abásolo L.
    Scand J Rheumatol; 2013 Jan 12; 42(6):433-6. PubMed ID: 23742043
    [Abstract] [Full Text] [Related]

  • 20. Common polymorphisms in the folate pathway predict efficacy of combination regimens containing methotrexate and sulfasalazine in early rheumatoid arthritis.
    James HM, Gillis D, Hissaria P, Lester S, Somogyi AA, Cleland LG, Proudman SM.
    J Rheumatol; 2008 Apr 12; 35(4):562-71. PubMed ID: 18322994
    [Abstract] [Full Text] [Related]

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