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454 related items for PubMed ID: 22982526

  • 1. Docking studies, synthesis, characterization of some novel oxazine substituted 9-anilinoacridine derivatives and evaluation for their antioxidant and anticancer activities as topoisomerase II inhibitors.
    Kalirajan R, Kulshrestha V, Sankar S, Jubie S.
    Eur J Med Chem; 2012 Oct; 56():217-24. PubMed ID: 22982526
    [Abstract] [Full Text] [Related]

  • 2. Synthesis, cytotoxicity and topoisomerase II inhibitory activity of lomefloxacin derivatives.
    Zhou Y, Xu X, Sun Y, Wang H, Sun H, You Q.
    Bioorg Med Chem Lett; 2013 May 15; 23(10):2974-8. PubMed ID: 23566520
    [Abstract] [Full Text] [Related]

  • 3. Design, synthesis and systematic evaluation of cytotoxic 3-heteroarylisoquinolinamines as topoisomerases inhibitors.
    My Van HT, Woo H, Jeong HM, Khadka DB, Yang SH, Zhao C, Jin Y, Lee ES, Youl Lee K, Kwon Y, Cho WJ.
    Eur J Med Chem; 2014 Jul 23; 82():181-94. PubMed ID: 24904965
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and pharmacological evaluation of novel bisindolylalkanes analogues.
    Song YL, Dong YF, Yang T, Zhang CC, Su LM, Huang X, Zhang DN, Yang GL, Liu YX.
    Bioorg Med Chem; 2013 Dec 15; 21(24):7624-7. PubMed ID: 24262885
    [Abstract] [Full Text] [Related]

  • 5. Synthesis, biological evaluation, and molecular docking study of 3-(3'-heteroatom substituted-2'-hydroxy-1'-propyloxy) xanthone analogues as novel topoisomerase IIα catalytic inhibitor.
    Jun KY, Lee EY, Jung MJ, Lee OH, Lee ES, Park Choo HY, Na Y, Kwon Y.
    Eur J Med Chem; 2011 Jun 15; 46(6):1964-71. PubMed ID: 21419530
    [Abstract] [Full Text] [Related]

  • 6. Synthesis, cytotoxicity, DNA binding and topoisomerase II inhibition of cassiarin A derivatives.
    Luesakul U, Palaga T, Krusong K, Ngamrojanavanich N, Vilaivan T, Puthong S, Muangsin N.
    Bioorg Med Chem Lett; 2014 Jul 01; 24(13):2845-50. PubMed ID: 24835201
    [Abstract] [Full Text] [Related]

  • 7. New derivatives of 11-methyl-6-[2-(dimethylamino)ethyl]-6H-indolo[2,3-b]quinoline as cytotoxic DNA topoisomerase II inhibitors.
    Luniewski W, Wietrzyk J, Godlewska J, Switalska M, Piskozub M, Peczynska-Czoch W, Kaczmarek L.
    Bioorg Med Chem Lett; 2012 Oct 01; 22(19):6103-7. PubMed ID: 22944121
    [Abstract] [Full Text] [Related]

  • 8. The 1'-substituent on the anilino ring of the antitumor drug amsacrine is a critical element for topoisomerase II inhibition and cytotoxicity.
    Rene B, Fosse P, Khelifa T, Jacquemin-Sablon A, Bailly C.
    Mol Pharmacol; 1996 Feb 01; 49(2):343-50. PubMed ID: 8632768
    [Abstract] [Full Text] [Related]

  • 9. Novel ciprofloxacin hybrids using biology oriented drug synthesis (BIODS) approach: Anticancer activity, effects on cell cycle profile, caspase-3 mediated apoptosis, topoisomerase II inhibition, and antibacterial activity.
    Kassab AE, Gedawy EM.
    Eur J Med Chem; 2018 Apr 25; 150():403-418. PubMed ID: 29547830
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and biological evaluation of benzo[a]phenazine derivatives as a dual inhibitor of topoisomerase I and II.
    Zhuo ST, Li CY, Hu MH, Chen SB, Yao PF, Huang SL, Ou TM, Tan JH, An LK, Li D, Gu LQ, Huang ZS.
    Org Biomol Chem; 2013 Jun 28; 11(24):3989-4005. PubMed ID: 23657605
    [Abstract] [Full Text] [Related]

  • 11. N-fused imidazoles as novel anticancer agents that inhibit catalytic activity of topoisomerase IIα and induce apoptosis in G1/S phase.
    Baviskar AT, Madaan C, Preet R, Mohapatra P, Jain V, Agarwal A, Guchhait SK, Kundu CN, Banerjee UC, Bharatam PV.
    J Med Chem; 2011 Jul 28; 54(14):5013-30. PubMed ID: 21644529
    [Abstract] [Full Text] [Related]

  • 12. Pyrroloquinolinone-based dual topoisomerase I/II inhibitor.
    Dalla Via L, Marzaro G, Ferrarese A, Gia O, Chilin A.
    Eur J Med Chem; 2014 Apr 22; 77():103-9. PubMed ID: 24631729
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and evaluation of novel podophyllotoxin analogs.
    Li J, Hua HM, Tang YB, Zhang S, Ohkoshi E, Lee KH, Xiao Zy.
    Bioorg Med Chem Lett; 2012 Jul 01; 22(13):4293-5. PubMed ID: 22658864
    [Abstract] [Full Text] [Related]

  • 14. Novel Thiazine Substituted 9-Anilinoacridines: Synthesis, Antitumour Activity and Structure Activity Relationships.
    Kalirajan R, Gaurav K, Pandiselvi A, Gowramma B, Sankar S.
    Anticancer Agents Med Chem; 2019 Jul 01; 19(11):1350-1358. PubMed ID: 30961512
    [Abstract] [Full Text] [Related]

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  • 18. Synthesis, biological evaluation and modeling studies of terphenyl topoisomerase IIα inhibitors as anticancer agents.
    Qiu J, Zhao B, Zhong W, Shen Y, Lin H.
    Eur J Med Chem; 2015 Apr 13; 94():427-35. PubMed ID: 25800514
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  • 20. Synthesis of podophyllotoxin linked β-carboline congeners as potential anticancer agents and DNA topoisomerase II inhibitors.
    Sathish M, Kavitha B, Nayak VL, Tangella Y, Ajitha A, Nekkanti S, Alarifi A, Shankaraiah N, Nagesh N, Kamal A.
    Eur J Med Chem; 2018 Jan 20; 144():557-571. PubMed ID: 29289881
    [Abstract] [Full Text] [Related]

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