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355 related items for PubMed ID: 22983443

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  • 3. Chromatin modifications induced by the AML1-ETO fusion protein reversibly silence its genomic targets through AML1 and Sp1 binding motifs.
    Maiques-Diaz A, Chou FS, Wunderlich M, Gómez-López G, Jacinto FV, Rodriguez-Perales S, Larrayoz MJ, Calasanz MJ, Mulloy JC, Cigudosa JC, Alvarez S.
    Leukemia; 2012 Jun; 26(6):1329-37. PubMed ID: 22289984
    [Abstract] [Full Text] [Related]

  • 4. Chromatin accessibility, p300, and histone acetylation define PML-RARα and AML1-ETO binding sites in acute myeloid leukemia.
    Saeed S, Logie C, Francoijs KJ, Frigè G, Romanenghi M, Nielsen FG, Raats L, Shahhoseini M, Huynen M, Altucci L, Minucci S, Martens JH, Stunnenberg HG.
    Blood; 2012 Oct 11; 120(15):3058-68. PubMed ID: 22923494
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  • 5. Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding.
    Ptasinska A, Assi SA, Mannari D, James SR, Williamson D, Dunne J, Hoogenkamp M, Wu M, Care M, McNeill H, Cauchy P, Cullen M, Tooze RM, Tenen DG, Young BD, Cockerill PN, Westhead DR, Heidenreich O, Bonifer C.
    Leukemia; 2012 Aug 11; 26(8):1829-41. PubMed ID: 22343733
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  • 6. Definition of a small core transcriptional circuit regulated by AML1-ETO.
    Stengel KR, Ellis JD, Spielman CL, Bomber ML, Hiebert SW.
    Mol Cell; 2021 Feb 04; 81(3):530-545.e5. PubMed ID: 33382982
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  • 7. The myeloid master regulator transcription factor PU.1 is inactivated by AML1-ETO in t(8;21) myeloid leukemia.
    Vangala RK, Heiss-Neumann MS, Rangatia JS, Singh SM, Schoch C, Tenen DG, Hiddemann W, Behre G.
    Blood; 2003 Jan 01; 101(1):270-7. PubMed ID: 12393465
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  • 9. The oncofusion protein FUS-ERG targets key hematopoietic regulators and modulates the all-trans retinoic acid signaling pathway in t(16;21) acute myeloid leukemia.
    Sotoca AM, Prange KH, Reijnders B, Mandoli A, Nguyen LN, Stunnenberg HG, Martens JH.
    Oncogene; 2016 Apr 14; 35(15):1965-76. PubMed ID: 26148230
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  • 10. Genome-wide studies identify a novel interplay between AML1 and AML1/ETO in t(8;21) acute myeloid leukemia.
    Li Y, Wang H, Wang X, Jin W, Tan Y, Fang H, Chen S, Chen Z, Wang K.
    Blood; 2016 Jan 14; 127(2):233-42. PubMed ID: 26546158
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  • 11. UBASH3B/Sts-1-CBL axis regulates myeloid proliferation in human preleukemia induced by AML1-ETO.
    Goyama S, Schibler J, Gasilina A, Shrestha M, Lin S, Link KA, Chen J, Whitman SP, Bloomfield CD, Nicolet D, Assi SA, Ptasinska A, Heidenreich O, Bonifer C, Kitamura T, Nassar NN, Mulloy JC.
    Leukemia; 2016 Mar 14; 30(3):728-39. PubMed ID: 26449661
    [Abstract] [Full Text] [Related]

  • 12. ETO and AML1 phosphoproteins are expressed in CD34+ hematopoietic progenitors: implications for t(8;21) leukemogenesis and monitoring residual disease.
    Erickson PF, Dessev G, Lasher RS, Philips G, Robinson M, Drabkin HA.
    Blood; 1996 Sep 01; 88(5):1813-23. PubMed ID: 8781439
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  • 13. The leukemogenic t(8;21) fusion protein AML1-ETO controls rRNA genes and associates with nucleolar-organizing regions at mitotic chromosomes.
    Bakshi R, Zaidi SK, Pande S, Hassan MQ, Young DW, Montecino M, Lian JB, van Wijnen AJ, Stein JL, Stein GS.
    J Cell Sci; 2008 Dec 01; 121(Pt 23):3981-90. PubMed ID: 19001502
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  • 14. Epigenetic Silencing of Eyes Absent 4 Gene by Acute Myeloid Leukemia 1-Eight-twenty-one Oncoprotein Contributes to Leukemogenesis in t(8;21) Acute Myeloid Leukemia.
    Huang S, Jiang MM, Chen GF, Qian K, Gao HH, Guan W, Shi JL, Liu AQ, Liu J, Wang BH, Li YH, Yu L.
    Chin Med J (Engl); 2016 Jun 05; 129(11):1355-62. PubMed ID: 27231175
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  • 15. A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis.
    Sun XJ, Wang Z, Wang L, Jiang Y, Kost N, Soong TD, Chen WY, Tang Z, Nakadai T, Elemento O, Fischle W, Melnick A, Patel DJ, Nimer SD, Roeder RG.
    Nature; 2013 Aug 01; 500(7460):93-7. PubMed ID: 23812588
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  • 16. Targeting AML1/ETO-histone deacetylase repressor complex: a novel mechanism for valproic acid-mediated gene expression and cellular differentiation in AML1/ETO-positive acute myeloid leukemia cells.
    Liu S, Klisovic RB, Vukosavljevic T, Yu J, Paschka P, Huynh L, Pang J, Neviani P, Liu Z, Blum W, Chan KK, Perrotti D, Marcucci G.
    J Pharmacol Exp Ther; 2007 Jun 01; 321(3):953-60. PubMed ID: 17389244
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  • 17. AML1/ETO proteins control POU4F1/BRN3A expression and function in t(8;21) acute myeloid leukemia.
    Dunne J, Gascoyne DM, Lister TA, Brady HJ, Heidenreich O, Young BD.
    Cancer Res; 2010 May 15; 70(10):3985-95. PubMed ID: 20460523
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  • 18. The AML1-ETO fusion gene and the FLT3 length mutation collaborate in inducing acute leukemia in mice.
    Schessl C, Rawat VP, Cusan M, Deshpande A, Kohl TM, Rosten PM, Spiekermann K, Humphries RK, Schnittger S, Kern W, Hiddemann W, Quintanilla-Martinez L, Bohlander SK, Feuring-Buske M, Buske C.
    J Clin Invest; 2005 Aug 15; 115(8):2159-68. PubMed ID: 16025155
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  • 19. Histone deacetylase 3 preferentially binds and collaborates with the transcription factor RUNX1 to repress AML1-ETO-dependent transcription in t(8;21) AML.
    Guo C, Li J, Steinauer N, Wong M, Wu B, Dickson A, Kalkum M, Zhang J.
    J Biol Chem; 2020 Mar 27; 295(13):4212-4223. PubMed ID: 32071087
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  • 20. Epigenetic silencing of microRNA-193a contributes to leukemogenesis in t(8;21) acute myeloid leukemia by activating the PTEN/PI3K signal pathway.
    Li Y, Gao L, Luo X, Wang L, Gao X, Wang W, Sun J, Dou L, Li J, Xu C, Wang L, Zhou M, Jiang M, Zhou J, Caligiuri MA, Nervi C, Bloomfield CD, Marcucci G, Yu L.
    Blood; 2013 Jan 17; 121(3):499-509. PubMed ID: 23223432
    [Abstract] [Full Text] [Related]


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