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407 related items for PubMed ID: 22989565

  • 1. The transcription factor KLF2 mediates hepatic endothelial protection and paracrine endothelial-stellate cell deactivation induced by statins.
    Marrone G, Russo L, Rosado E, Hide D, García-Cardeña G, García-Pagán JC, Bosch J, Gracia-Sancho J.
    J Hepatol; 2013 Jan; 58(1):98-103. PubMed ID: 22989565
    [Abstract] [Full Text] [Related]

  • 2. KLF2 exerts antifibrotic and vasoprotective effects in cirrhotic rat livers: behind the molecular mechanisms of statins.
    Marrone G, Maeso-Díaz R, García-Cardena G, Abraldes JG, García-Pagán JC, Bosch J, Gracia-Sancho J.
    Gut; 2015 Sep; 64(9):1434-43. PubMed ID: 25500203
    [Abstract] [Full Text] [Related]

  • 3. Endothelial expression of transcription factor Kruppel-like factor 2 and its vasoprotective target genes in the normal and cirrhotic rat liver.
    Gracia-Sancho J, Russo L, García-Calderó H, García-Pagán JC, García-Cardeña G, Bosch J.
    Gut; 2011 Apr; 60(4):517-24. PubMed ID: 21112949
    [Abstract] [Full Text] [Related]

  • 4. Addition of simvastatin to cold storage solution prevents endothelial dysfunction in explanted rat livers.
    Russo L, Gracia-Sancho J, García-Calderó H, Marrone G, García-Pagán JC, García-Cardeña G, Bosch J.
    Hepatology; 2012 Mar; 55(3):921-30. PubMed ID: 22031447
    [Abstract] [Full Text] [Related]

  • 5. Effect of simvastatin on Kruppel-like factor2, endothelial nitric oxide synthase and thrombomodulin expression in endothelial cells under shear stress.
    Rossi J, Rouleau L, Tardif JC, Leask RL.
    Life Sci; 2010 Jul 17; 87(3-4):92-9. PubMed ID: 20493886
    [Abstract] [Full Text] [Related]

  • 6. Antioxidant effects of statins via S-nitrosylation and activation of thioredoxin in endothelial cells: a novel vasculoprotective function of statins.
    Haendeler J, Hoffmann J, Zeiher AM, Dimmeler S.
    Circulation; 2004 Aug 17; 110(7):856-61. PubMed ID: 15289372
    [Abstract] [Full Text] [Related]

  • 7. Simvastatin suppresses the proangiogenic microenvironment of human hepatic stellate cells via the Kruppel-like factor 2 pathway.
    Miao Q, Zeng X, Ma G, Li N, Liu Y, Luo T, Lian J, Chen S.
    Rev Esp Enferm Dig; 2015 Feb 17; 107(2):63-71. PubMed ID: 25659387
    [Abstract] [Full Text] [Related]

  • 8. Cross-talk between autophagy and KLF2 determines endothelial cell phenotype and microvascular function in acute liver injury.
    Guixé-Muntet S, de Mesquita FC, Vila S, Hernández-Gea V, Peralta C, García-Pagán JC, Bosch J, Gracia-Sancho J.
    J Hepatol; 2017 Jan 17; 66(1):86-94. PubMed ID: 27545498
    [Abstract] [Full Text] [Related]

  • 9. Statin-mediated cytoprotection of human vascular endothelial cells: a role for Kruppel-like factor 2-dependent induction of heme oxygenase-1.
    Ali F, Hamdulay SS, Kinderlerer AR, Boyle JJ, Lidington EA, Yamaguchi T, Soares MP, Haskard DO, Randi AM, Mason JC.
    J Thromb Haemost; 2007 Dec 17; 5(12):2537-46. PubMed ID: 17927807
    [Abstract] [Full Text] [Related]

  • 10. Atorvastatin counteracts high glucose-induced Krüppel-like factor 2 suppression in human umbilical vein endothelial cells.
    Liu YS, Xu DL, Huang ZW, Hao L, Wang X, Lu QH.
    Postgrad Med; 2015 Jun 17; 127(5):446-54. PubMed ID: 25927862
    [Abstract] [Full Text] [Related]

  • 11. Shear stress sustains atheroprotective endothelial KLF2 expression more potently than statins through mRNA stabilization.
    van Thienen JV, Fledderus JO, Dekker RJ, Rohlena J, van Ijzendoorn GA, Kootstra NA, Pannekoek H, Horrevoets AJ.
    Cardiovasc Res; 2006 Nov 01; 72(2):231-40. PubMed ID: 16945356
    [Abstract] [Full Text] [Related]

  • 12. Kruppel-like factor 2 as a novel mediator of statin effects in endothelial cells.
    Sen-Banerjee S, Mir S, Lin Z, Hamik A, Atkins GB, Das H, Banerjee P, Kumar A, Jain MK.
    Circulation; 2005 Aug 02; 112(5):720-6. PubMed ID: 16043642
    [Abstract] [Full Text] [Related]

  • 13. Statins normalize vascular lysyl oxidase down-regulation induced by proatherogenic risk factors.
    Rodríguez C, Alcudia JF, Martínez-González J, Guadall A, Raposo B, Sánchez-Gómez S, Badimon L.
    Cardiovasc Res; 2009 Aug 01; 83(3):595-603. PubMed ID: 19406911
    [Abstract] [Full Text] [Related]

  • 14. FOXO1 impairs whereas statin protects endothelial function in diabetes through reciprocal regulation of Kruppel-like factor 2.
    Lee HY, Youn SW, Cho HJ, Kwon YW, Lee SW, Kim SJ, Park YB, Oh BH, Kim HS.
    Cardiovasc Res; 2013 Jan 01; 97(1):143-52. PubMed ID: 23002242
    [Abstract] [Full Text] [Related]

  • 15. Statins enhance migratory capacity by upregulation of the telomere repeat-binding factor TRF2 in endothelial progenitor cells.
    Spyridopoulos I, Haendeler J, Urbich C, Brummendorf TH, Oh H, Schneider MD, Zeiher AM, Dimmeler S.
    Circulation; 2004 Nov 09; 110(19):3136-42. PubMed ID: 15520325
    [Abstract] [Full Text] [Related]

  • 16. Improvement of portal hypertension and hepatic blood flow in cirrhotic rats by oestrogen.
    Sakamoto M, Ueno T, Nakamura T, Sakata R, Hasimoto O, Torimura T, Sata M.
    Eur J Clin Invest; 2005 Mar 09; 35(3):220-5. PubMed ID: 15733078
    [Abstract] [Full Text] [Related]

  • 17. Atorvastatin attenuates hepatic fibrosis in rats after bile duct ligation via decreased turnover of hepatic stellate cells.
    Trebicka J, Hennenberg M, Odenthal M, Shir K, Klein S, Granzow M, Vogt A, Dienes HP, Lammert F, Reichen J, Heller J, Sauerbruch T.
    J Hepatol; 2010 Oct 09; 53(4):702-12. PubMed ID: 20633948
    [Abstract] [Full Text] [Related]

  • 18. Nitroflurbiprofen, a nitric oxide-releasing cyclooxygenase inhibitor, improves cirrhotic portal hypertension in rats.
    Laleman W, Van Landeghem L, Van der Elst I, Zeegers M, Fevery J, Nevens F.
    Gastroenterology; 2007 Feb 09; 132(2):709-19. PubMed ID: 17258737
    [Abstract] [Full Text] [Related]

  • 19. Effects of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors, atorvastatin and simvastatin, on the expression of endothelin-1 and endothelial nitric oxide synthase in vascular endothelial cells.
    Hernández-Perera O, Pérez-Sala D, Navarro-Antolín J, Sánchez-Pascuala R, Hernández G, Díaz C, Lamas S.
    J Clin Invest; 1998 Jun 15; 101(12):2711-9. PubMed ID: 9637705
    [Abstract] [Full Text] [Related]

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