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174 related items for PubMed ID: 2299619

  • 1. Synthesis and antihypertensive activity of 4-(1,2-dihydro-2-oxo-1-pyridyl)-2H-1-benzopyrans and related compounds, new potassium channel activators.
    Bergmann R, Gericke R.
    J Med Chem; 1990 Feb; 33(2):492-504. PubMed ID: 2299619
    [Abstract] [Full Text] [Related]

  • 2. 4-Heterocyclyloxy-2H-1-benzopyran potassium channel activators.
    Bergmann R, Eiermann V, Gericke R.
    J Med Chem; 1990 Oct; 33(10):2759-67. PubMed ID: 2213828
    [Abstract] [Full Text] [Related]

  • 3. 2,2-Dialkylnaphthalen-1-ones as new potassium channel activators.
    Almansa C, Gómez LA, Cavalcanti FL, Rodríguez R, Carceller E, Bartrolí J, García-Rafanell J, Forn J.
    J Med Chem; 1993 Jul 23; 36(15):2121-33. PubMed ID: 8340916
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and antihypertensive activity of 4-(diazabicyclo[4.1.0]-heptenyloxy)benzopyran derivatives and their analogues.
    Horino H, Mimura T, Kagechika K, Ohta M, Kubo H, Kitagawa M.
    Chem Pharm Bull (Tokyo); 1998 Apr 23; 46(4):602-9. PubMed ID: 9579035
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and antihypertensive activity of 4-(cyclic amido)-2H-1-benzopyrans.
    Ashwood VA, Buckingham RE, Cassidy F, Evans JM, Faruk EA, Hamilton TC, Nash DJ, Stemp G, Willcocks K.
    J Med Chem; 1986 Nov 23; 29(11):2194-201. PubMed ID: 3783581
    [Abstract] [Full Text] [Related]

  • 6. 3-Methyl-2H-1-benzopyran potassium channel activators.
    Gericke R, Harting J, Lues I, Schittenhelm C.
    J Med Chem; 1991 Oct 23; 34(10):3074-85. PubMed ID: 1920358
    [Abstract] [Full Text] [Related]

  • 7. Synthesis and antihypertensive activity of substituted trans-4-amino-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-3-ols.
    Evans JM, Fake CS, Hamilton TC, Poyser RH, Watts EA.
    J Med Chem; 1983 Nov 23; 26(11):1582-9. PubMed ID: 6631915
    [Abstract] [Full Text] [Related]

  • 8. Synthesis and antihypertensive activity of 4-(substituted-carbonylamino)-2H-1-benzopyrans.
    Ashwood VA, Cassidy F, Coldwell MC, Evans JM, Hamilton TC, Howlett DR, Smith DM, Stemp G.
    J Med Chem; 1990 Sep 23; 33(9):2667-72. PubMed ID: 2391705
    [Abstract] [Full Text] [Related]

  • 9. Variation in the aromatic ring of cromakalim: antihypertensive activity of pyranopyridines and 6-alkyl-2H-1-benzopyrans.
    Burrell G, Cassidy F, Evans JM, Lightowler D, Stemp G.
    J Med Chem; 1990 Nov 23; 33(11):3023-7. PubMed ID: 2231601
    [Abstract] [Full Text] [Related]

  • 10. Thiophene systems. 14. Synthesis and antihypertensive activity of novel 7-(cyclic amido)-6-hydroxythieno[3,2-b]pyrans and related compounds as new potassium channel activators.
    Sanfilippo PJ, McNally JJ, Press JB, Fitzpatrick LJ, Urbanski MJ, Katz LB, Giardino E, Falotico R, Salata J, Moore JB.
    J Med Chem; 1992 Nov 13; 35(23):4425-33. PubMed ID: 1447742
    [Abstract] [Full Text] [Related]

  • 11. Relaxant activity of 4-amido-3,4-dihydro-2H-1-benzopyran-3-ols and 4-amido-2H-1-benzopyrans on guinea pig isolated trachealis.
    Buckle DR, Arch JR, Fenwick AE, Houge-Frydrych CS, Pinto IL, Smith DG, Taylor SG, Tedder JM.
    J Med Chem; 1990 Nov 13; 33(11):3028-34. PubMed ID: 2231602
    [Abstract] [Full Text] [Related]

  • 12. Synthesis and antihypertensive activity of 6,7-disubstituted trans-4-amino-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-3-ols.
    Evans JM, Fake CS, Hamilton TC, Poyser RH, Showell GA.
    J Med Chem; 1984 Sep 13; 27(9):1127-31. PubMed ID: 6471067
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and selective coronary vasodilatory activity of 3,4-dihydro-2,2-bis(methoxymethyl)-2H-1-benzopyran-3-ol derivatives: novel potassium channel openers.
    Cho H, Katoh S, Sayama S, Murakami K, Nakanishi H, Kajimoto Y, Ueno H, Kawasaki H, Aisaka K, Uchida I.
    J Med Chem; 1996 Sep 13; 39(19):3797-805. PubMed ID: 8809167
    [Abstract] [Full Text] [Related]

  • 14. Synthesis and antihypertensive activity of 3-[(substituted-carbonyl)amino]-2H-1-benzopyrans.
    Cassidy F, Evans JM, Hadley MS, Haladij AH, Leach PE, Stemp G.
    J Med Chem; 1992 May 01; 35(9):1623-7. PubMed ID: 1578490
    [Abstract] [Full Text] [Related]

  • 15. The influence of substituents in 3-position on the activity of chroman-type potassium channel activators.
    Bergmann R, Gericke R.
    Arch Pharm (Weinheim); 1994 Mar 01; 327(3):169-73. PubMed ID: 8179475
    [Abstract] [Full Text] [Related]

  • 16. Novel potassium channel activators: synthesis and structure-activity relationship studies of 3,4-dihydro-2H-1,4-benzoxazine derivatives.
    Matsumoto Y, Tsuzuki R, Matsuhisa A, Takayama K, Yoden T, Uchida W, Asano M, Fujita S, Yanagisawa I, Fujikura T.
    Chem Pharm Bull (Tokyo); 1996 Jan 01; 44(1):103-14. PubMed ID: 8582029
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and antihypertensive activity of 1,4-dihydropyridine derivatives with a 4-(disubstituted phenyl) ring and an aminoalkyl ester group: highly potent and long-lasting calcium antagonists.
    Kanno H, Yamaguchi H, Okamiya Y, Sunakawa K, Takeshita T, Naruchi T.
    Chem Pharm Bull (Tokyo); 1992 Aug 01; 40(8):2049-54. PubMed ID: 1423758
    [Abstract] [Full Text] [Related]

  • 18. Synthesis and antihypertensive activity of pyran oxygen and amide nitrogen replacement analogues of the potassium channel activator cromakalim.
    Ashwood VA, Cassidy F, Evans JM, Gagliardi S, Stemp G.
    J Med Chem; 1991 Nov 01; 34(11):3261-7. PubMed ID: 1659637
    [Abstract] [Full Text] [Related]

  • 19. Potassium channel activators based on the benzopyran substructure: synthesis and activity of the C-8 substituent.
    Thompson R, Doggrell S, Hoberg JO.
    Bioorg Med Chem; 2003 Apr 17; 11(8):1663-8. PubMed ID: 12659752
    [Abstract] [Full Text] [Related]

  • 20. RWJ 26629, a new potassium channel opener and vascular smooth muscle relaxant: a potential antihypertensive and antianginal agent.
    Katz LB, Giardino EC, Salata JJ, Moore JB, Falotico R.
    J Pharmacol Exp Ther; 1993 Nov 17; 267(2):648-56. PubMed ID: 8246137
    [Abstract] [Full Text] [Related]


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