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Journal Abstract Search
301 related items for PubMed ID: 23030300
1. The basis for carbapenem hydrolysis by class A β-lactamases: a combined investigation using crystallography and simulations. Fonseca F, Chudyk EI, van der Kamp MW, Correia A, Mulholland AJ, Spencer J. J Am Chem Soc; 2012 Nov 07; 134(44):18275-85. PubMed ID: 23030300 [Abstract] [Full Text] [Related]
2. QM/MM Simulations Reveal the Determinants of Carbapenemase Activity in Class A β-Lactamases. Chudyk EI, Beer M, Limb MAL, Jones CA, Spencer J, van der Kamp MW, Mulholland AJ. ACS Infect Dis; 2022 Aug 12; 8(8):1521-1532. PubMed ID: 35877936 [Abstract] [Full Text] [Related]
4. Molecular characterization of a carbapenem-hydrolyzing class A beta-lactamase, SFC-1, from Serratia fonticola UTAD54. Henriques I, Moura A, Alves A, Saavedra MJ, Correia A. Antimicrob Agents Chemother; 2004 Jun 12; 48(6):2321-4. PubMed ID: 15155245 [Abstract] [Full Text] [Related]
5. Perturbing the general base residue Glu166 in the active site of class A β-lactamase leads to enhanced carbapenem binding and acylation. Pan X, Wong WT, He Y, Jiang Y, Zhao Y. Biochemistry; 2014 Aug 26; 53(33):5414-23. PubMed ID: 25020031 [Abstract] [Full Text] [Related]
7. KPC-2 β-lactamase enables carbapenem antibiotic resistance through fast deacylation of the covalent intermediate. Mehta SC, Furey IM, Pemberton OA, Boragine DM, Chen Y, Palzkill T. J Biol Chem; 2021 Aug 26; 296():100155. PubMed ID: 33273017 [Abstract] [Full Text] [Related]
8. Local interactions with the Glu166 base and the conformation of an active site loop play key roles in carbapenem hydrolysis by the KPC-2 β-lactamase. Furey IM, Mehta SC, Sankaran B, Hu L, Prasad BVV, Palzkill T. J Biol Chem; 2021 Aug 26; 296():100799. PubMed ID: 34022225 [Abstract] [Full Text] [Related]
10. The role of conserved surface hydrophobic residues in the carbapenemase activity of the class D β-lactamases. Toth M, Smith CA, Antunes NT, Stewart NK, Maltz L, Vakulenko SB. Acta Crystallogr D Struct Biol; 2017 Aug 01; 73(Pt 8):692-701. PubMed ID: 28777084 [Abstract] [Full Text] [Related]
11. Mechanistic Basis of OXA-48-like β-Lactamases' Hydrolysis of Carbapenems. Stojanoski V, Hu L, Sankaran B, Wang F, Tao P, Prasad BVV, Palzkill T. ACS Infect Dis; 2021 Feb 12; 7(2):445-460. PubMed ID: 33492952 [Abstract] [Full Text] [Related]
12. Crystal structure of the OXA-48 beta-lactamase reveals mechanistic diversity among class D carbapenemases. Docquier JD, Calderone V, De Luca F, Benvenuti M, Giuliani F, Bellucci L, Tafi A, Nordmann P, Botta M, Rossolini GM, Mangani S. Chem Biol; 2009 May 29; 16(5):540-7. PubMed ID: 19477418 [Abstract] [Full Text] [Related]
13. SME-3, a novel member of the Serratia marcescens SME family of carbapenem-hydrolyzing beta-lactamases. Queenan AM, Shang W, Schreckenberger P, Lolans K, Bush K, Quinn J. Antimicrob Agents Chemother; 2006 Oct 29; 50(10):3485-7. PubMed ID: 17005839 [Abstract] [Full Text] [Related]
14. Modified Penicillin Molecule with Carbapenem-Like Stereochemistry Specifically Inhibits Class C β-Lactamases. Pan X, He Y, Chen T, Chan KF, Zhao Y. Antimicrob Agents Chemother; 2017 Dec 29; 61(12):. PubMed ID: 28971874 [Abstract] [Full Text] [Related]
15. Kinetic and structural requirements for carbapenemase activity in GES-type β-lactamases. Stewart NK, Smith CA, Frase H, Black DJ, Vakulenko SB. Biochemistry; 2015 Jan 20; 54(2):588-97. PubMed ID: 25485972 [Abstract] [Full Text] [Related]
16. Crystal structures of the class D beta-lactamase OXA-13 in the native form and in complex with meropenem. Pernot L, Frénois F, Rybkine T, L'Hermite G, Petrella S, Delettré J, Jarlier V, Collatz E, Sougakoff W. J Mol Biol; 2001 Jul 20; 310(4):859-74. PubMed ID: 11453693 [Abstract] [Full Text] [Related]
18. Inhibitor-resistant class A beta-lactamases: consequences of the Ser130-to-Gly mutation seen in Apo and tazobactam structures of the SHV-1 variant. Sun T, Bethel CR, Bonomo RA, Knox JR. Biochemistry; 2004 Nov 09; 43(44):14111-7. PubMed ID: 15518561 [Abstract] [Full Text] [Related]
20. Modeling study on a hydrolytic mechanism of class A beta-lactamases. Ishiguro M, Imajo S. J Med Chem; 1996 May 24; 39(11):2207-18. PubMed ID: 8667364 [Abstract] [Full Text] [Related] Page: [Next] [New Search]