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Journal Abstract Search

116 related items for PubMed ID: 23104179

  • 1. Novel pyrimidine-2,4-diamine derivative suppresses the cell viability and spindle assembly checkpoint activity by targeting Aurora kinases.
    Salmela AL, Pouwels J, Mäki-Jouppila J, Kohonen P, Toivonen P, Kallio L, Kallio M.
    Carcinogenesis; 2013 Feb; 34(2):436-45. PubMed ID: 23104179
    [Abstract] [Full Text] [Related]

  • 2. The flavonoid eupatorin inactivates the mitotic checkpoint leading to polyploidy and apoptosis.
    Salmela AL, Pouwels J, Kukkonen-Macchi A, Waris S, Toivonen P, Jaakkola K, Mäki-Jouppila J, Kallio L, Kallio MJ.
    Exp Cell Res; 2012 Mar 10; 318(5):578-92. PubMed ID: 22227008
    [Abstract] [Full Text] [Related]

  • 3. Pharmacologic abrogation of the mitotic spindle checkpoint by an indolocarbazole discovered by cellular screening efficiently kills cancer cells.
    Stolz A, Vogel C, Schneider V, Ertych N, Kienitz A, Yu H, Bastians H.
    Cancer Res; 2009 May 01; 69(9):3874-83. PubMed ID: 19366805
    [Abstract] [Full Text] [Related]

  • 4. Polo-like kinase 1 inhibitor BI2536 causes mitotic catastrophe following activation of the spindle assembly checkpoint in non-small cell lung cancer cells.
    Choi M, Kim W, Cheon MG, Lee CW, Kim JE.
    Cancer Lett; 2015 Feb 28; 357(2):591-601. PubMed ID: 25524551
    [Abstract] [Full Text] [Related]

  • 5. Trivalent dimethylarsenic compound induces histone H3 phosphorylation and abnormal localization of Aurora B kinase in HepG2 cells.
    Suzuki T, Miyazaki K, Kita K, Ochi T.
    Toxicol Appl Pharmacol; 2009 Dec 15; 241(3):275-82. PubMed ID: 19716834
    [Abstract] [Full Text] [Related]

  • 6. Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores.
    Ditchfield C, Johnson VL, Tighe A, Ellston R, Haworth C, Johnson T, Mortlock A, Keen N, Taylor SS.
    J Cell Biol; 2003 Apr 28; 161(2):267-80. PubMed ID: 12719470
    [Abstract] [Full Text] [Related]

  • 7. Characterization of Alisertib (MLN8237), an investigational small-molecule inhibitor of aurora A kinase using novel in vivo pharmacodynamic assays.
    Manfredi MG, Ecsedy JA, Chakravarty A, Silverman L, Zhang M, Hoar KM, Stroud SG, Chen W, Shinde V, Huck JJ, Wysong DR, Janowick DA, Hyer ML, Leroy PJ, Gershman RE, Silva MD, Germanos MS, Bolen JB, Claiborne CF, Sells TB.
    Clin Cancer Res; 2011 Dec 15; 17(24):7614-24. PubMed ID: 22016509
    [Abstract] [Full Text] [Related]

  • 8. BubR1 is required for a sustained mitotic spindle checkpoint arrest in human cancer cells treated with tubulin-targeting pyrrolo-1,5-benzoxazepines.
    Greene LM, Campiani G, Lawler M, Williams DC, Zisterer DM.
    Mol Pharmacol; 2008 Feb 15; 73(2):419-30. PubMed ID: 17991869
    [Abstract] [Full Text] [Related]

  • 9. Mitotic arrest and slippage induced by pharmacological inhibition of Polo-like kinase 1.
    Raab M, Krämer A, Hehlgans S, Sanhaji M, Kurunci-Csacsko E, Dötsch C, Bug G, Ottmann O, Becker S, Pachl F, Kuster B, Strebhardt K.
    Mol Oncol; 2015 Jan 15; 9(1):140-54. PubMed ID: 25169932
    [Abstract] [Full Text] [Related]

  • 10. Curcumin-induced mitotic spindle defect and cell cycle arrest in human bladder cancer cells occurs partly through inhibition of aurora A.
    Liu HS, Ke CS, Cheng HC, Huang CY, Su CL.
    Mol Pharmacol; 2011 Oct 15; 80(4):638-46. PubMed ID: 21757545
    [Abstract] [Full Text] [Related]

  • 11. Small-molecule inhibition of Aurora kinases triggers spindle checkpoint-independent apoptosis in cancer cells.
    Sun L, Li D, Dong X, Yu H, Dong JT, Zhang C, Lu X, Zhou J.
    Biochem Pharmacol; 2008 Mar 01; 75(5):1027-34. PubMed ID: 18163976
    [Abstract] [Full Text] [Related]

  • 12. Inhibition of microtubule assembly in tumor cells by 3-bromoacetylamino benzoylurea, a new cancericidal compound.
    Jiang JD, Wang Y, Roboz J, Strauchen J, Holland JF, Bekesi JG.
    Cancer Res; 1998 May 15; 58(10):2126-33. PubMed ID: 9605756
    [Abstract] [Full Text] [Related]

  • 13. Growth suppression and mitotic defect induced by JNJ-7706621, an inhibitor of cyclin-dependent kinases and aurora kinases.
    Matsuhashi A, Ohno T, Kimura M, Hara A, Saio M, Nagano A, Kawai G, Saitou M, Takigami I, Yamada K, Okano Y, Shimizu K.
    Curr Cancer Drug Targets; 2012 Jul 15; 12(6):625-39. PubMed ID: 22463590
    [Abstract] [Full Text] [Related]

  • 14. The small-molecule inhibitor BI 2536 reveals novel insights into mitotic roles of polo-like kinase 1.
    Lénárt P, Petronczki M, Steegmaier M, Di Fiore B, Lipp JJ, Hoffmann M, Rettig WJ, Kraut N, Peters JM.
    Curr Biol; 2007 Feb 20; 17(4):304-15. PubMed ID: 17291761
    [Abstract] [Full Text] [Related]

  • 15. Validating Aurora B as an anti-cancer drug target.
    Girdler F, Gascoigne KE, Eyers PA, Hartmuth S, Crafter C, Foote KM, Keen NJ, Taylor SS.
    J Cell Sci; 2006 Sep 01; 119(Pt 17):3664-75. PubMed ID: 16912073
    [Abstract] [Full Text] [Related]

  • 16. The nuclear scaffold protein SAF-A is required for kinetochore-microtubule attachment and contributes to the targeting of Aurora-A to mitotic spindles.
    Ma N, Matsunaga S, Morimoto A, Sakashita G, Urano T, Uchiyama S, Fukui K.
    J Cell Sci; 2011 Feb 01; 124(Pt 3):394-404. PubMed ID: 21242313
    [Abstract] [Full Text] [Related]

  • 17. 16-Hydroxycleroda-3,13-dien-15,16-olide deregulates PI3K and Aurora B activities that involve in cancer cell apoptosis.
    Lin YH, Lee CC, Chan WL, Chang WH, Wu YC, Chang JG.
    Toxicology; 2011 Jul 11; 285(1-2):72-80. PubMed ID: 21530604
    [Abstract] [Full Text] [Related]

  • 18. Histone deacetylase inhibitors disrupt the mitotic spindle assembly checkpoint by targeting histone and nonhistone proteins.
    Gabrielli B, Brown M.
    Adv Cancer Res; 2012 Jul 11; 116():1-37. PubMed ID: 23088867
    [Abstract] [Full Text] [Related]

  • 19. Development and biological evaluation of a novel aurora A kinase inhibitor.
    Sardon T, Cottin T, Xu J, Giannis A, Vernos I.
    Chembiochem; 2009 Feb 13; 10(3):464-78. PubMed ID: 19199284
    [Abstract] [Full Text] [Related]

  • 20. WJD008, a dual phosphatidylinositol 3-kinase (PI3K)/mammalian target of rapamycin inhibitor, prevents PI3K signaling and inhibits the proliferation of transformed cells with oncogenic PI3K mutant.
    Li T, Wang J, Wang X, Yang N, Chen SM, Tong LJ, Yang CH, Meng LH, Ding J.
    J Pharmacol Exp Ther; 2010 Sep 01; 334(3):830-8. PubMed ID: 20522531
    [Abstract] [Full Text] [Related]

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