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212 related items for PubMed ID: 23132899

  • 1. Stichoposide C induces apoptosis through the generation of ceramide in leukemia and colorectal cancer cells and shows in vivo antitumor activity.
    Yun SH, Park ES, Shin SW, Na YW, Han JY, Jeong JS, Shastina VV, Stonik VA, Park JI, Kwak JY.
    Clin Cancer Res; 2012 Nov 01; 18(21):5934-48. PubMed ID: 23132899
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  • 2. 15d-PGJ2 induces apoptosis by reactive oxygen species-mediated inactivation of Akt in leukemia and colorectal cancer cells and shows in vivo antitumor activity.
    Shin SW, Seo CY, Han H, Han JY, Jeong JS, Kwak JY, Park JI.
    Clin Cancer Res; 2009 Sep 01; 15(17):5414-25. PubMed ID: 19690198
    [Abstract] [Full Text] [Related]

  • 3. By activating Fas/ceramide synthase 6/p38 kinase in lipid rafts, stichoposide D inhibits growth of leukemia xenografts.
    Yun SH, Park ES, Shin SW, Ju MH, Han JY, Jeong JS, Kim SH, Stonik VA, Kwak JY, Park JI.
    Oncotarget; 2015 Sep 29; 6(29):27596-612. PubMed ID: 26318294
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  • 4. Acid sphingomyelinase activation requires caspase-8 but not p53 nor reactive oxygen species during Fas-induced apoptosis in human glioma cells.
    Sawada M, Nakashima S, Kiyono T, Yamada J, Hara S, Nakagawa M, Shinoda J, Sakai N.
    Exp Cell Res; 2002 Feb 15; 273(2):157-68. PubMed ID: 11822871
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  • 5. Holotoxin A₁ Induces Apoptosis by Activating Acid Sphingomyelinase and Neutral Sphingomyelinase in K562 and Human Primary Leukemia Cells.
    Yun SH, Sim EH, Han SH, Han JY, Kim SH, Silchenko AS, Stonik VA, Park JI.
    Mar Drugs; 2018 Apr 10; 16(4):. PubMed ID: 29642569
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  • 6. Withanolide D induces apoptosis in leukemia by targeting the activation of neutral sphingomyelinase-ceramide cascade mediated by synergistic activation of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase.
    Mondal S, Mandal C, Sangwan R, Chandra S, Mandal C.
    Mol Cancer; 2010 Sep 13; 9():239. PubMed ID: 20836852
    [Abstract] [Full Text] [Related]

  • 7. Coadministration of histone deacetylase inhibitors and perifosine synergistically induces apoptosis in human leukemia cells through Akt and ERK1/2 inactivation and the generation of ceramide and reactive oxygen species.
    Rahmani M, Reese E, Dai Y, Bauer C, Payne SG, Dent P, Spiegel S, Grant S.
    Cancer Res; 2005 Mar 15; 65(6):2422-32. PubMed ID: 15781658
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  • 9. A novel dietary triterpene Lupeol induces fas-mediated apoptotic death of androgen-sensitive prostate cancer cells and inhibits tumor growth in a xenograft model.
    Saleem M, Kweon MH, Yun JM, Adhami VM, Khan N, Syed DN, Mukhtar H.
    Cancer Res; 2005 Dec 01; 65(23):11203-13. PubMed ID: 16322271
    [Abstract] [Full Text] [Related]

  • 10. Apolipoprotein C-I induces apoptosis in human aortic smooth muscle cells via recruiting neutral sphingomyelinase.
    Kolmakova A, Kwiterovich P, Virgil D, Alaupovic P, Knight-Gibson C, Martin SF, Chatterjee S.
    Arterioscler Thromb Vasc Biol; 2004 Feb 01; 24(2):264-9. PubMed ID: 14670935
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  • 12. Curcumin induces apoptosis of multidrug-resistant human leukemia HL60 cells by complex pathways leading to ceramide accumulation.
    Shakor AB, Atia M, Ismail IA, Alshehri A, El-Refaey H, Kwiatkowska K, Sobota A.
    Biochim Biophys Acta; 2014 Dec 01; 1841(12):1672-82. PubMed ID: 25240837
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  • 15. The newly synthesized 2-(3-hydroxy-5-methoxyphenyl)-6,7-methylenedioxyquinolin-4-one triggers cell apoptosis through induction of oxidative stress and upregulation of the p38 MAPK signaling pathway in HL-60 human leukemia cells.
    Cheng YY, Yang JS, Tsai SC, Liaw CC, Chung JG, Huang LJ, Lee KH, Lu CC, Chien HC, Tsuzuki M, Kuo SC.
    Oncol Rep; 2012 Oct 01; 28(4):1482-90. PubMed ID: 22825350
    [Abstract] [Full Text] [Related]

  • 16. Ceramide is the key mediator of oxidative stress-induced apoptosis in retinal photoreceptor cells.
    Sanvicens N, Cotter TG.
    J Neurochem; 2006 Sep 01; 98(5):1432-44. PubMed ID: 16923157
    [Abstract] [Full Text] [Related]

  • 17. FTY720 induced Bcl-associated and Fas-independent apoptosis in human renal cancer cells in vitro and significantly reduced in vivo tumor growth in mouse xenograft.
    Ubai T, Azuma H, Kotake Y, Inamoto T, Takahara K, Ito Y, Kiyama S, Sakamoto T, Horie S, Muto S, Takahara S, Otsuki Y, Katsuoka Y.
    Anticancer Res; 2007 Sep 01; 27(1A):75-88. PubMed ID: 17352219
    [Abstract] [Full Text] [Related]

  • 18. Delphinidin 3-sambubioside, a Hibiscus anthocyanin, induces apoptosis in human leukemia cells through reactive oxygen species-mediated mitochondrial pathway.
    Hou DX, Tong X, Terahara N, Luo D, Fujii M.
    Arch Biochem Biophys; 2005 Aug 01; 440(1):101-9. PubMed ID: 16018963
    [Abstract] [Full Text] [Related]

  • 19. Differential effects of triterpene glycosides, frondoside A and cucumarioside A2-2 isolated from sea cucumbers on caspase activation and apoptosis of human leukemia cells.
    Jin JO, Shastina VV, Shin SW, Xu Q, Park JI, Rasskazov VA, Avilov SA, Fedorov SN, Stonik VA, Kwak JY.
    FEBS Lett; 2009 Feb 18; 583(4):697-702. PubMed ID: 19162021
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  • 20. The induction of G2/M cell-cycle arrest and apoptosis by cucurbitacin E is associated with increased phosphorylation of eIF2alpha in leukemia cells.
    Li Y, Wang R, Ma E, Deng Y, Wang X, Xiao J, Jing Y.
    Anticancer Drugs; 2010 Apr 18; 21(4):389-400. PubMed ID: 20110807
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