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Journal Abstract Search

278 related items for PubMed ID: 23145024

  • 1. Pgc-1α overexpression downregulates Pitx3 and increases susceptibility to MPTP toxicity associated with decreased Bdnf.
    Clark J, Silvaggi JM, Kiselak T, Zheng K, Clore EL, Dai Y, Bass CE, Simon DK.
    PLoS One; 2012; 7(11):e48925. PubMed ID: 23145024
    [Abstract] [Full Text] [Related]

  • 2. Transgenic expression and activation of PGC-1α protect dopaminergic neurons in the MPTP mouse model of Parkinson's disease.
    Mudò G, Mäkelä J, Di Liberto V, Tselykh TV, Olivieri M, Piepponen P, Eriksson O, Mälkiä A, Bonomo A, Kairisalo M, Aguirre JA, Korhonen L, Belluardo N, Lindholm D.
    Cell Mol Life Sci; 2012 Apr; 69(7):1153-65. PubMed ID: 21984601
    [Abstract] [Full Text] [Related]

  • 3. Beneficial effects of PGC-1α in the substantia nigra of a mouse model of MPTP-induced dopaminergic neurotoxicity.
    Wang Y, Chen C, Huang W, Huang M, Wang J, Chen X, Ye Q.
    Aging (Albany NY); 2019 Oct 21; 11(20):8937-8950. PubMed ID: 31634150
    [Abstract] [Full Text] [Related]

  • 4. Teaghrelin protected dopaminergic neurons in MPTP-induced Parkinson's disease animal model by promoting PINK1/Parkin-mediated mitophagy and AMPK/SIRT1/PGC1-α-mediated mitochondrial biogenesis.
    Jhuo CF, Chen CJ, Tzen JTC, Chen WY.
    Environ Toxicol; 2024 Jul 21; 39(7):4022-4034. PubMed ID: 38622810
    [Abstract] [Full Text] [Related]

  • 5. Tetramethylpyrazine nitrone exerts neuroprotection via activation of PGC-1α/Nrf2 pathway in Parkinson's disease models.
    Guo B, Zheng C, Cao J, Luo F, Li H, Hu S, Mingyuan Lee S, Yang X, Zhang G, Zhang Z, Sun Y, Wang Y.
    J Adv Res; 2024 Oct 21; 64():195-211. PubMed ID: 37989471
    [Abstract] [Full Text] [Related]

  • 6. Sustained expression of PGC-1α in the rat nigrostriatal system selectively impairs dopaminergic function.
    Ciron C, Lengacher S, Dusonchet J, Aebischer P, Schneider BL.
    Hum Mol Genet; 2012 Apr 15; 21(8):1861-76. PubMed ID: 22246294
    [Abstract] [Full Text] [Related]

  • 7. The TrkB-positive dopaminergic neurons are less sensitive to MPTP insult in the substantia nigra of adult C57/BL mice.
    Ding YX, Xia Y, Jiao XY, Duan L, Yu J, Wang X, Chen LW.
    Neurochem Res; 2011 Oct 15; 36(10):1759-66. PubMed ID: 21562748
    [Abstract] [Full Text] [Related]

  • 8. Single low doses of MPTP decrease tyrosine hydroxylase expression in the absence of overt neuron loss.
    Alam G, Edler M, Burchfield S, Richardson JR.
    Neurotoxicology; 2017 May 15; 60():99-106. PubMed ID: 28377118
    [Abstract] [Full Text] [Related]

  • 9. PGC-1α activity in nigral dopamine neurons determines vulnerability to α-synuclein.
    Ciron C, Zheng L, Bobela W, Knott GW, Leone TC, Kelly DP, Schneider BL.
    Acta Neuropathol Commun; 2015 Apr 01; 3():16. PubMed ID: 25853296
    [Abstract] [Full Text] [Related]

  • 10. The transcription factor Pitx3 is expressed selectively in midbrain dopaminergic neurons susceptible to neurodegenerative stress.
    Luk KC, Rymar VV, van den Munckhof P, Nicolau S, Steriade C, Bifsha P, Drouin J, Sadikot AF.
    J Neurochem; 2013 Jun 01; 125(6):932-43. PubMed ID: 23331067
    [Abstract] [Full Text] [Related]

  • 11. Delivery of CDNF by AAV-mediated gene transfer protects dopamine neurons and regulates ER stress and inflammation in an acute MPTP mouse model of Parkinson's disease.
    Nam J, Richie CT, Harvey BK, Voutilainen MH.
    Sci Rep; 2024 Jul 17; 14(1):16487. PubMed ID: 39019902
    [Abstract] [Full Text] [Related]

  • 12. TRPV4 contributes to ER stress and inflammation: implications for Parkinson's disease.
    Liu N, Bai L, Lu Z, Gu R, Zhao D, Yan F, Bai J.
    J Neuroinflammation; 2022 Jan 29; 19(1):26. PubMed ID: 35093118
    [Abstract] [Full Text] [Related]

  • 13. Liraglutide Regulates Mitochondrial Quality Control System Through PGC-1α in a Mouse Model of Parkinson's Disease.
    Wu P, Dong Y, Chen J, Guan T, Cao B, Zhang Y, Qi Y, Guan Z, Wang Y.
    Neurotox Res; 2022 Feb 29; 40(1):286-297. PubMed ID: 35043376
    [Abstract] [Full Text] [Related]

  • 14. Overexpression of Parkinson's disease-associated alpha-synucleinA53T by recombinant adeno-associated virus in mice does not increase the vulnerability of dopaminergic neurons to MPTP.
    Dong Z, Ferger B, Feldon J, Büeler H.
    J Neurobiol; 2002 Oct 29; 53(1):1-10. PubMed ID: 12360578
    [Abstract] [Full Text] [Related]

  • 15. Hyperbaric Oxygen Therapy Improves Parkinson's Disease by Promoting Mitochondrial Biogenesis via the SIRT-1/PGC-1α Pathway.
    Hsu HT, Yang YL, Chang WH, Fang WY, Huang SH, Chou SH, Lo YC.
    Biomolecules; 2022 Apr 30; 12(5):. PubMed ID: 35625589
    [Abstract] [Full Text] [Related]

  • 16. Admixing of MPTP-Resistant and Susceptible Mice Strains Augments Nigrostriatal Neuronal Correlates to Resist MPTP-Induced Neurodegeneration.
    Vidyadhara DJ, Yarreiphang H, Raju TR, Alladi PA.
    Mol Neurobiol; 2017 Oct 30; 54(8):6148-6162. PubMed ID: 27704331
    [Abstract] [Full Text] [Related]

  • 17. Downregulation of miR-124 in MPTP-treated mouse model of Parkinson's disease and MPP iodide-treated MN9D cells modulates the expression of the calpain/cdk5 pathway proteins.
    Kanagaraj N, Beiping H, Dheen ST, Tay SS.
    Neuroscience; 2014 Jul 11; 272():167-79. PubMed ID: 24792712
    [Abstract] [Full Text] [Related]

  • 18. Metformin lowers α-synuclein phosphorylation and upregulates neurotrophic factor in the MPTP mouse model of Parkinson's disease.
    Katila N, Bhurtel S, Shadfar S, Srivastav S, Neupane S, Ojha U, Jeong GS, Choi DY.
    Neuropharmacology; 2017 Oct 11; 125():396-407. PubMed ID: 28807678
    [Abstract] [Full Text] [Related]

  • 19. Folic Acid Rescues Dopaminergic Neurons in MPTP-Induced Mice by Inhibiting the NLRP3 Inflammasome and Ameliorating Mitochondrial Impairment.
    Jia Y, Li J, Wang Y, Ma Y, Chen L, Zhang H, Xue M, Liang H.
    J Agric Food Chem; 2024 Mar 20; 72(11):5734-5745. PubMed ID: 38453725
    [Abstract] [Full Text] [Related]

  • 20. Neuroprotective Effects of Bifidobacterium animalis subsp. lactis NJ241 in a Mouse Model of Parkinson's Disease: Implications for Gut Microbiota and PGC-1α.
    Dong Y, Qi Y, Chen J, Han S, Su W, Ma X, Yu Y, Wang Y.
    Mol Neurobiol; 2024 Oct 20; 61(10):7534-7548. PubMed ID: 38409641
    [Abstract] [Full Text] [Related]

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