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188 related items for PubMed ID: 23153057
1. Assessment of cytochrome P450 (1A2, 2B6, 2C9 and 3A4) induction in cryopreserved human hepatocytes cultured in 48-well plates using the cocktail strategy. Gerin B, Dell'Aiera S, Richert L, Smith S, Chanteux H. Xenobiotica; 2013 Apr; 43(4):320-35. PubMed ID: 23153057 [Abstract] [Full Text] [Related]
2. Follow-up to the pre-validation of a harmonised protocol for assessment of CYP induction responses in freshly isolated and cryopreserved human hepatocytes with respect to culture format, treatment, positive reference inducers and incubation conditions. Abadie-Viollon C, Martin H, Blanchard N, Pekthong D, Bachellier P, Mantion G, Heyd B, Schuler F, Coassolo P, Alexandre E, Richert L. Toxicol In Vitro; 2010 Feb; 24(1):346-56. PubMed ID: 19497360 [Abstract] [Full Text] [Related]
4. Plateable cryopreserved human hepatocytes for the assessment of cytochrome P450 inducibility: experimental condition-related variables affecting their response to inducers. Alexandre E, Baze A, Parmentier C, Desbans C, Pekthong D, Gerin B, Wack C, Bachellier P, Heyd B, Weber JC, Richert L. Xenobiotica; 2012 Oct; 42(10):968-79. PubMed ID: 22515431 [Abstract] [Full Text] [Related]
5. Evaluation of 23 lots of commercially available cryopreserved hepatocytes for induction assays of human cytochromes P450. Yajima K, Uno Y, Murayama N, Uehara S, Shimizu M, Nakamura C, Iwasaki K, Utoh M, Yamazaki H. Drug Metab Dispos; 2014 May; 42(5):867-71. PubMed ID: 24553381 [Abstract] [Full Text] [Related]
6. The effects of gender, age, ethnicity, and liver cirrhosis on cytochrome P450 enzyme activity in human liver microsomes and inducibility in cultured human hepatocytes. Parkinson A, Mudra DR, Johnson C, Dwyer A, Carroll KM. Toxicol Appl Pharmacol; 2004 Sep 15; 199(3):193-209. PubMed ID: 15364537 [Abstract] [Full Text] [Related]
7. Expression and induction potential of cytochromes P450 in human cryopreserved hepatocytes. Roymans D, Annaert P, Van Houdt J, Weygers A, Noukens J, Sensenhauser C, Silva J, Van Looveren C, Hendrickx J, Mannens G, Meuldermans W. Drug Metab Dispos; 2005 Jul 15; 33(7):1004-16. PubMed ID: 15802389 [Abstract] [Full Text] [Related]
8. Profiling induction of cytochrome p450 enzyme activity by statins using a new liquid chromatography-tandem mass spectrometry cocktail assay in human hepatocytes. Feidt DM, Klein K, Hofmann U, Riedmaier S, Knobeloch D, Thasler WE, Weiss TS, Schwab M, Zanger UM. Drug Metab Dispos; 2010 Sep 15; 38(9):1589-97. PubMed ID: 20551241 [Abstract] [Full Text] [Related]
10. Application of a substrate cocktail approach in the assessment of cytochrome P450 induction using cultured human hepatocytes. Pelletier RD, Lai WG, Wong YN. J Biomol Screen; 2013 Feb 15; 18(2):199-210. PubMed ID: 23071008 [Abstract] [Full Text] [Related]
12. Inter-laboratory evaluation of the response of primary human hepatocyte cultures to model CYP inducers - a European Centre for Validation of Alternative Methods (ECVAM) - funded pre-validation study. Richert L, Abadie C, Bonet A, Heyd B, Mantion G, Alexandre E, Bachellier P, Kingston S, Pattenden C, Illouz S, Dennison A, Hoffmann S, Coecke S. Toxicol In Vitro; 2010 Feb 15; 24(1):335-45. PubMed ID: 19497361 [Abstract] [Full Text] [Related]
13. Cytochrome P450 enzyme levels in HepG2 cells and cryopreserved primary human hepatocytes and their induction in HepG2 cells. Westerink WM, Schoonen WG. Toxicol In Vitro; 2007 Dec 15; 21(8):1581-91. PubMed ID: 17637504 [Abstract] [Full Text] [Related]
14. Determination of cytochrome P450 1A2 and cytochrome P450 3A4 induction in cryopreserved human hepatocytes. Roymans D, Van Looveren C, Leone A, Parker JB, McMillian M, Johnson MD, Koganti A, Gilissen R, Silber P, Mannens G, Meuldermans W. Biochem Pharmacol; 2004 Feb 01; 67(3):427-37. PubMed ID: 15037195 [Abstract] [Full Text] [Related]
16. A sensitive and high-throughput LC-MS/MS method for inhibition assay of seven major cytochrome P450s in human liver microsomes using an in vitro cocktail of probe substrates. Liu LY, Han YL, Zhu JH, Yu Q, Yang QJ, Lu J, Guo C. Biomed Chromatogr; 2015 Mar 01; 29(3):437-44. PubMed ID: 25098274 [Abstract] [Full Text] [Related]
17. Cryopreserved human hepatocytes as alternative in vitro model for cytochrome p450 induction studies. Garcia M, Rager J, Wang Q, Strab R, Hidalgo IJ, Owen A, Li J. In Vitro Cell Dev Biol Anim; 2003 Mar 01; 39(7):283-7. PubMed ID: 14599235 [Abstract] [Full Text] [Related]
19. Predictions of cytochrome P450-mediated drug-drug interactions using cryopreserved human hepatocytes: comparison of plasma and protein-free media incubation conditions. Mao J, Mohutsky MA, Harrelson JP, Wrighton SA, Hall SD. Drug Metab Dispos; 2012 Apr 01; 40(4):706-16. PubMed ID: 22228749 [Abstract] [Full Text] [Related]
20. In vitro studies investigating the interactions between degarelix, a decapeptide gonadotropin-releasing hormone blocker, and cytochrome P450. Sonesson A, Rasmussen BB. Basic Clin Pharmacol Toxicol; 2011 Sep 01; 109(3):195-202. PubMed ID: 21496210 [Abstract] [Full Text] [Related] Page: [Next] [New Search]