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444 related items for PubMed ID: 23169665

  • 1. Mutual protection of ribosomal proteins L5 and L11 from degradation is essential for p53 activation upon ribosomal biogenesis stress.
    Bursać S, Brdovčak MC, Pfannkuchen M, Orsolić I, Golomb L, Zhu Y, Katz C, Daftuar L, Grabušić K, Vukelić I, Filić V, Oren M, Prives C, Volarevic S.
    Proc Natl Acad Sci U S A; 2012 Dec 11; 109(50):20467-72. PubMed ID: 23169665
    [Abstract] [Full Text] [Related]

  • 2. Perturbation of 60 S ribosomal biogenesis results in ribosomal protein L5- and L11-dependent p53 activation.
    Sun XX, Wang YG, Xirodimas DP, Dai MS.
    J Biol Chem; 2010 Aug 13; 285(33):25812-21. PubMed ID: 20554519
    [Abstract] [Full Text] [Related]

  • 3. Inhibition of MDM2-mediated p53 ubiquitination and degradation by ribosomal protein L5.
    Dai MS, Lu H.
    J Biol Chem; 2004 Oct 22; 279(43):44475-82. PubMed ID: 15308643
    [Abstract] [Full Text] [Related]

  • 4. PML regulates p53 stability by sequestering Mdm2 to the nucleolus.
    Bernardi R, Scaglioni PP, Bergmann S, Horn HF, Vousden KH, Pandolfi PP.
    Nat Cell Biol; 2004 Jul 22; 6(7):665-72. PubMed ID: 15195100
    [Abstract] [Full Text] [Related]

  • 5. Regulation of the MDM2-p53 pathway by ribosomal protein L11 involves a post-ubiquitination mechanism.
    Dai MS, Shi D, Jin Y, Sun XX, Zhang Y, Grossman SR, Lu H.
    J Biol Chem; 2006 Aug 25; 281(34):24304-13. PubMed ID: 16803902
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  • 10. Ribosomal stress induces L11- and p53-dependent apoptosis in mouse pluripotent stem cells.
    Morgado-Palacin L, Llanos S, Serrano M.
    Cell Cycle; 2012 Feb 01; 11(3):503-10. PubMed ID: 22262176
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  • 11. Regulation of nucleolar signalling to p53 through NEDDylation of L11.
    Sundqvist A, Liu G, Mirsaliotis A, Xirodimas DP.
    EMBO Rep; 2009 Oct 01; 10(10):1132-9. PubMed ID: 19713960
    [Abstract] [Full Text] [Related]

  • 12. Cancer-associated mutations in the MDM2 zinc finger domain disrupt ribosomal protein interaction and attenuate MDM2-induced p53 degradation.
    Lindström MS, Jin A, Deisenroth C, White Wolf G, Zhang Y.
    Mol Cell Biol; 2007 Feb 01; 27(3):1056-68. PubMed ID: 17116689
    [Abstract] [Full Text] [Related]

  • 13. Depletion of ribosomal protein L37 occurs in response to DNA damage and activates p53 through the L11/MDM2 pathway.
    Llanos S, Serrano M.
    Cell Cycle; 2010 Oct 01; 9(19):4005-12. PubMed ID: 20935493
    [Abstract] [Full Text] [Related]

  • 14. Recruitment of RPL11 at promoter sites of p53-regulated genes upon nucleolar stress through NEDD8 and in an Mdm2-dependent manner.
    Mahata B, Sundqvist A, Xirodimas DP.
    Oncogene; 2012 Jun 21; 31(25):3060-71. PubMed ID: 22081073
    [Abstract] [Full Text] [Related]

  • 15. Mycophenolic acid activation of p53 requires ribosomal proteins L5 and L11.
    Sun XX, Dai MS, Lu H.
    J Biol Chem; 2008 May 02; 283(18):12387-92. PubMed ID: 18305114
    [Abstract] [Full Text] [Related]

  • 16. Absence of nucleolar disruption after impairment of 40S ribosome biogenesis reveals an rpL11-translation-dependent mechanism of p53 induction.
    Fumagalli S, Di Cara A, Neb-Gulati A, Natt F, Schwemberger S, Hall J, Babcock GF, Bernardi R, Pandolfi PP, Thomas G.
    Nat Cell Biol; 2009 Apr 02; 11(4):501-8. PubMed ID: 19287375
    [Abstract] [Full Text] [Related]

  • 17. Ribosomal protein L23 activates p53 by inhibiting MDM2 function in response to ribosomal perturbation but not to translation inhibition.
    Dai MS, Zeng SX, Jin Y, Sun XX, David L, Lu H.
    Mol Cell Biol; 2004 Sep 02; 24(17):7654-68. PubMed ID: 15314173
    [Abstract] [Full Text] [Related]

  • 18. PICT-1 is a key nucleolar sensor in DNA damage response signaling that regulates apoptosis through the RPL11-MDM2-p53 pathway.
    Chen H, Han L, Tsai H, Wang Z, Wu Y, Duo Y, Cao W, Chen L, Tan Z, Xu N, Huang X, Zhuang J, Huang L.
    Oncotarget; 2016 Dec 13; 7(50):83241-83257. PubMed ID: 27829214
    [Abstract] [Full Text] [Related]

  • 19. 5-fluorouracil activation of p53 involves an MDM2-ribosomal protein interaction.
    Sun XX, Dai MS, Lu H.
    J Biol Chem; 2007 Mar 16; 282(11):8052-9. PubMed ID: 17242401
    [Abstract] [Full Text] [Related]

  • 20. Perturbation of RNA Polymerase I transcription machinery by ablation of HEATR1 triggers the RPL5/RPL11-MDM2-p53 ribosome biogenesis stress checkpoint pathway in human cells.
    Turi Z, Senkyrikova M, Mistrik M, Bartek J, Moudry P.
    Cell Cycle; 2018 Mar 16; 17(1):92-101. PubMed ID: 29143558
    [Abstract] [Full Text] [Related]

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