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251 related items for PubMed ID: 23171048

  • 1. SNF8, a member of the ESCRT-II complex, interacts with TRPC6 and enhances its channel activity.
    Carrasquillo R, Tian D, Krishna S, Pollak MR, Greka A, Schlöndorff J.
    BMC Cell Biol; 2012 Nov 21; 13():33. PubMed ID: 23171048
    [Abstract] [Full Text] [Related]

  • 2. TRPC6 mutations associated with focal segmental glomerulosclerosis cause constitutive activation of NFAT-dependent transcription.
    Schlöndorff J, Del Camino D, Carrasquillo R, Lacey V, Pollak MR.
    Am J Physiol Cell Physiol; 2009 Mar 21; 296(3):C558-69. PubMed ID: 19129465
    [Abstract] [Full Text] [Related]

  • 3. Angiotensin II contributes to podocyte injury by increasing TRPC6 expression via an NFAT-mediated positive feedback signaling pathway.
    Nijenhuis T, Sloan AJ, Hoenderop JG, Flesche J, van Goor H, Kistler AD, Bakker M, Bindels RJ, de Boer RA, Möller CC, Hamming I, Navis G, Wetzels JF, Berden JH, Reiser J, Faul C, van der Vlag J.
    Am J Pathol; 2011 Oct 21; 179(4):1719-32. PubMed ID: 21839714
    [Abstract] [Full Text] [Related]

  • 4. Gain-of-function mutations in transient receptor potential C6 (TRPC6) activate extracellular signal-regulated kinases 1/2 (ERK1/2).
    Chiluiza D, Krishna S, Schumacher VA, Schlöndorff J.
    J Biol Chem; 2013 Jun 21; 288(25):18407-20. PubMed ID: 23645677
    [Abstract] [Full Text] [Related]

  • 5. Cyclic GMP/PKG-dependent inhibition of TRPC6 channel activity and expression negatively regulates cardiomyocyte NFAT activation Novel mechanism of cardiac stress modulation by PDE5 inhibition.
    Koitabashi N, Aiba T, Hesketh GG, Rowell J, Zhang M, Takimoto E, Tomaselli GF, Kass DA.
    J Mol Cell Cardiol; 2010 Apr 21; 48(4):713-24. PubMed ID: 19961855
    [Abstract] [Full Text] [Related]

  • 6. MxA, a member of the dynamin superfamily, interacts with the ankyrin-like repeat domain of TRPC.
    Lussier MP, Cayouette S, Lepage PK, Bernier CL, Francoeur N, St-Hilaire M, Pinard M, Boulay G.
    J Biol Chem; 2005 May 13; 280(19):19393-400. PubMed ID: 15757897
    [Abstract] [Full Text] [Related]

  • 7. Tyrosine phosphorylation-dependent activation of TRPC6 regulated by PLC-γ1 and nephrin: effect of mutations associated with focal segmental glomerulosclerosis.
    Kanda S, Harita Y, Shibagaki Y, Sekine T, Igarashi T, Inoue T, Hattori S.
    Mol Biol Cell; 2011 Jun 01; 22(11):1824-35. PubMed ID: 21471003
    [Abstract] [Full Text] [Related]

  • 8. New TRPC6 gain-of-function mutation in a non-consanguineous Dutch family with late-onset focal segmental glomerulosclerosis.
    Hofstra JM, Lainez S, van Kuijk WH, Schoots J, Baltissen MP, Hoefsloot LH, Knoers NV, Berden JH, Bindels RJ, van der Vlag J, Hoenderop JG, Wetzels JF, Nijenhuis T.
    Nephrol Dial Transplant; 2013 Jul 01; 28(7):1830-8. PubMed ID: 23291369
    [Abstract] [Full Text] [Related]

  • 9. Phosphodiesterase 5 inhibition ameliorates angiontensin II-induced podocyte dysmotility via the protein kinase G-mediated downregulation of TRPC6 activity.
    Hall G, Rowell J, Farinelli F, Gbadegesin RA, Lavin P, Wu G, Homstad A, Malone A, Lindsey T, Jiang R, Spurney R, Tomaselli GF, Kass DA, Winn MP.
    Am J Physiol Renal Physiol; 2014 Jun 15; 306(12):F1442-50. PubMed ID: 24740790
    [Abstract] [Full Text] [Related]

  • 10. Transient receptor potential canonical channel 6 links Ca2+ mishandling to cystic fibrosis transmembrane conductance regulator channel dysfunction in cystic fibrosis.
    Antigny F, Norez C, Dannhoffer L, Bertrand J, Raveau D, Corbi P, Jayle C, Becq F, Vandebrouck C.
    Am J Respir Cell Mol Biol; 2011 Jan 15; 44(1):83-90. PubMed ID: 20203293
    [Abstract] [Full Text] [Related]

  • 11. Transmembrane insertases and N-glycosylation critically determine synthesis, trafficking, and activity of the nonselective cation channel TRPC6.
    Talbot BE, Vandorpe DH, Stotter BR, Alper SL, Schlondorff JS.
    J Biol Chem; 2019 Aug 23; 294(34):12655-12669. PubMed ID: 31266804
    [Abstract] [Full Text] [Related]

  • 12. Role of endogenous TRPC6 channels in Ca2+ signal generation in A7r5 smooth muscle cells.
    Soboloff J, Spassova M, Xu W, He LP, Cuesta N, Gill DL.
    J Biol Chem; 2005 Dec 02; 280(48):39786-94. PubMed ID: 16204251
    [Abstract] [Full Text] [Related]

  • 13. A novel TRPC6 mutation that causes childhood FSGS.
    Heeringa SF, Möller CC, Du J, Yue L, Hinkes B, Chernin G, Vlangos CN, Hoyer PF, Reiser J, Hildebrandt F.
    PLoS One; 2009 Nov 10; 4(11):e7771. PubMed ID: 19936226
    [Abstract] [Full Text] [Related]

  • 14. Canonical transient receptor potential channel (TRPC)3 and TRPC6 associate with large-conductance Ca2+-activated K+ (BKCa) channels: role in BKCa trafficking to the surface of cultured podocytes.
    Kim EY, Alvarez-Baron CP, Dryer SE.
    Mol Pharmacol; 2009 Mar 10; 75(3):466-77. PubMed ID: 19052171
    [Abstract] [Full Text] [Related]

  • 15. TRPC Channels in Proteinuric Kidney Diseases.
    Hall G, Wang L, Spurney RF.
    Cells; 2019 Dec 23; 9(1):. PubMed ID: 31877991
    [Abstract] [Full Text] [Related]

  • 16. Identification and functional analysis of a novel TRPC6 mutation associated with late onset familial focal segmental glomerulosclerosis in Chinese patients.
    Zhu B, Chen N, Wang ZH, Pan XX, Ren H, Zhang W, Wang WM.
    Mutat Res; 2009 May 12; 664(1-2):84-90. PubMed ID: 19124028
    [Abstract] [Full Text] [Related]

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  • 18. TRPC6 fulfills a calcineurin signaling circuit during pathologic cardiac remodeling.
    Kuwahara K, Wang Y, McAnally J, Richardson JA, Bassel-Duby R, Hill JA, Olson EN.
    J Clin Invest; 2006 Dec 12; 116(12):3114-26. PubMed ID: 17099778
    [Abstract] [Full Text] [Related]

  • 19. Molecular determinants for cardiovascular TRPC6 channel regulation by Ca2+/calmodulin-dependent kinase II.
    Shi J, Geshi N, Takahashi S, Kiyonaka S, Ichikawa J, Hu Y, Mori Y, Ito Y, Inoue R.
    J Physiol; 2013 Jun 01; 591(11):2851-66. PubMed ID: 23529130
    [Abstract] [Full Text] [Related]

  • 20. Inhibition of TRPC6 channel activity contributes to the antihypertrophic effects of natriuretic peptides-guanylyl cyclase-A signaling in the heart.
    Kinoshita H, Kuwahara K, Nishida M, Jian Z, Rong X, Kiyonaka S, Kuwabara Y, Kurose H, Inoue R, Mori Y, Li Y, Nakagawa Y, Usami S, Fujiwara M, Yamada Y, Minami T, Ueshima K, Nakao K.
    Circ Res; 2010 Jun 25; 106(12):1849-60. PubMed ID: 20448219
    [Abstract] [Full Text] [Related]

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