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Journal Abstract Search

148 related items for PubMed ID: 2317163

  • 1. Unexpected failure of bile acid malabsorption to stimulate cholesterol synthesis in sitosterolemia with xanthomatosis. Comparison with lovastatin.
    Nguyen L, Salen G, Shefer S, Shore V, Tint GS, Ness G.
    Arteriosclerosis; 1990; 10(2):289-97. PubMed ID: 2317163
    [Abstract] [Full Text] [Related]

  • 2. Decreased cholesterol biosynthesis in sitosterolemia with xanthomatosis: diminished mononuclear leukocyte 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and enzyme protein associated with increased low-density lipoprotein receptor function.
    Nguyen LB, Salen G, Shefer S, Tint GS, Shore V, Ness GC.
    Metabolism; 1990 Apr; 39(4):436-43. PubMed ID: 2325562
    [Abstract] [Full Text] [Related]

  • 3. Regulation of cholesterol biosynthesis in sitosterolemia: effects of lovastatin, cholestyramine, and dietary sterol restriction.
    Nguyen LB, Cobb M, Shefer S, Salen G, Ness GC, Tint GS.
    J Lipid Res; 1991 Dec; 32(12):1941-8. PubMed ID: 1816322
    [Abstract] [Full Text] [Related]

  • 4. A molecular defect in hepatic cholesterol biosynthesis in sitosterolemia with xanthomatosis.
    Nguyen LB, Shefer S, Salen G, Ness GC, Tint GS, Zaki FG, Rani I.
    J Clin Invest; 1990 Sep; 86(3):923-31. PubMed ID: 2394840
    [Abstract] [Full Text] [Related]

  • 5. The effect of abnormal plasma and cellular sterol content and composition on low density lipoprotein uptake and degradation by monocytes and lymphocytes in sitosterolemia with xanthomatosis.
    Nguyen LB, Shefer S, Salen G, Horak I, Tint GS, McNamara DJ.
    Metabolism; 1988 Apr; 37(4):346-51. PubMed ID: 3357417
    [Abstract] [Full Text] [Related]

  • 6. Macrophage 3-hydroxy-3-methylglutaryl coenzyme a reductase activity in sitosterolemia: effects of increased cellular cholesterol and sitosterol concentrations.
    Nguyen LB, Salen G, Shefer S, Tint GS, Ruiz F.
    Metabolism; 2001 Oct; 50(10):1224-9. PubMed ID: 11586498
    [Abstract] [Full Text] [Related]

  • 7. Increased sitosterol absorption, decreased removal, and expanded body pools compensate for reduced cholesterol synthesis in sitosterolemia with xanthomatosis.
    Salen G, Shore V, Tint GS, Forte T, Shefer S, Horak I, Horak E, Dayal B, Nguyen L, Batta AK.
    J Lipid Res; 1989 Sep; 30(9):1319-30. PubMed ID: 2600539
    [Abstract] [Full Text] [Related]

  • 8. Inverse relationship between plasma cholestanol concentrations and bile acid synthesis in sitosterolemia.
    Salen G, Batta AK, Tint GS, Shefer S, Ness GC.
    J Lipid Res; 1994 Oct; 35(10):1878-87. PubMed ID: 7852865
    [Abstract] [Full Text] [Related]

  • 9. Deficient ileal 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in sitosterolemia: sitosterol is not a feedback inhibitor of intestinal cholesterol biosynthesis.
    Nguyen LB, Salen G, Shefer S, Bullock J, Chen T, Tint GS, Chowdhary IR, Lerner S.
    Metabolism; 1994 Jul; 43(7):855-9. PubMed ID: 8028508
    [Abstract] [Full Text] [Related]

  • 10. Down-regulation of cholesterol biosynthesis in sitosterolemia: diminished activities of acetoacetyl-CoA thiolase, 3-hydroxy-3-methylglutaryl-CoA synthase, reductase, squalene synthase, and 7-dehydrocholesterol delta7-reductase in liver and mononuclear leukocytes.
    Honda A, Salen G, Nguyen LB, Tint GS, Batta AK, Shefer S.
    J Lipid Res; 1998 Jan; 39(1):44-50. PubMed ID: 9469584
    [Abstract] [Full Text] [Related]

  • 11. 3-Hydroxy-3-methylglutaryl-coenzyme A reductase activity is inhibited by cholesterol and up-regulated by sitosterol in sitosterolemic fibroblasts.
    Honda A, Salen G, Honda M, Batta AK, Tint GS, Xu G, Chen TS, Tanaka N, Shefer S.
    J Lab Clin Med; 2000 Feb; 135(2):174-9. PubMed ID: 10695663
    [Abstract] [Full Text] [Related]

  • 12. The effect of increased hepatic sitosterol on the regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and cholesterol 7 alpha-hydroxylase in the rat and sitosterolemic homozygotes.
    Shefer S, Salen G, Bullock J, Nguyen LB, Ness GC, Vhao Z, Belamarich PF, Chowdhary I, Lerner S, Batta AK.
    Hepatology; 1994 Jul; 20(1 Pt 1):213-9. PubMed ID: 8020891
    [Abstract] [Full Text] [Related]

  • 13. Abnormal metabolism of shellfish sterols in a patient with sitosterolemia and xanthomatosis.
    Gregg RE, Connor WE, Lin DS, Brewer HB.
    J Clin Invest; 1986 Jun; 77(6):1864-72. PubMed ID: 3711338
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  • 16. Lovastatin treatment inhibits sterol synthesis and induces HMG-CoA reductase activity in mononuclear leukocytes of normal subjects.
    Stone BG, Evans CD, Prigge WF, Duane WC, Gebhard RL.
    J Lipid Res; 1989 Dec; 30(12):1943-52. PubMed ID: 2621421
    [Abstract] [Full Text] [Related]

  • 17. Hepatic cholesterol and bile acid synthesis, low-density lipoprotein receptor function, and plasma and fecal sterol levels in mice: effects of apolipoprotein E deficiency and probucol or phytosterol treatment.
    Moghadasian MH, Nguyen LB, Shefer S, Salen G, Batta AK, Frohlich JJ.
    Metabolism; 2001 Jun; 50(6):708-14. PubMed ID: 11398149
    [Abstract] [Full Text] [Related]

  • 18. Competitive inhibition of bile acid synthesis by endogenous cholestanol and sitosterol in sitosterolemia with xanthomatosis. Effect on cholesterol 7 alpha-hydroxylase.
    Shefer S, Salen G, Nguyen L, Batta AK, Packin V, Tint GS, Hauser S.
    J Clin Invest; 1988 Dec; 82(6):1833-9. PubMed ID: 3143743
    [Abstract] [Full Text] [Related]

  • 19. Competitive inhibition of hepatic sterol 27-hydroxylase by sitosterol: decreased activity in sitosterolemia.
    Nguyen LB, Shefer S, Salen G, Tint SG, Batta AK.
    Proc Assoc Am Physicians; 1998 Dec; 110(1):32-9. PubMed ID: 9460081
    [Abstract] [Full Text] [Related]

  • 20. Azalanstat (RS-21607), a lanosterol 14 alpha-demethylase inhibitor with cholesterol-lowering activity.
    Burton PM, Swinney DC, Heller R, Dunlap B, Chiou M, Malonzo E, Haller J, Walker KA, Salari A, Murakami S.
    Biochem Pharmacol; 1995 Aug 08; 50(4):529-44. PubMed ID: 7646560
    [Abstract] [Full Text] [Related]

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