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446 related items for PubMed ID: 23172666

  • 1. Benzyl isothiocyanate induces protective autophagy in human prostate cancer cells via inhibition of mTOR signaling.
    Lin JF, Tsai TF, Liao PC, Lin YH, Lin YC, Chen HE, Chou KY, Hwang TI.
    Carcinogenesis; 2013 Feb; 34(2):406-14. PubMed ID: 23172666
    [Abstract] [Full Text] [Related]

  • 2. The roles of AIF and Endo G in the apoptotic effects of benzyl isothiocyanate on DU 145 human prostate cancer cells via the mitochondrial signaling pathway.
    Liu KC, Huang YT, Wu PP, Ji BC, Yang JS, Yang JL, Chiu TH, Chueh FS, Chung JG.
    Int J Oncol; 2011 Mar; 38(3):787-96. PubMed ID: 21206973
    [Abstract] [Full Text] [Related]

  • 3. Rottlerin induces autophagy and apoptosis in prostate cancer stem cells via PI3K/Akt/mTOR signaling pathway.
    Kumar D, Shankar S, Srivastava RK.
    Cancer Lett; 2014 Feb 28; 343(2):179-89. PubMed ID: 24125861
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  • 4. Embelin inhibits growth and induces apoptosis through the suppression of Akt/mTOR/S6K1 signaling cascades.
    Kim SW, Kim SM, Bae H, Nam D, Lee JH, Lee SG, Shim BS, Kim SH, Ahn KS, Choi SH, Sethi G, Ahn KS.
    Prostate; 2013 Feb 15; 73(3):296-305. PubMed ID: 22887478
    [Abstract] [Full Text] [Related]

  • 5. Geraniol induces cooperative interaction of apoptosis and autophagy to elicit cell death in PC-3 prostate cancer cells.
    Kim SH, Park EJ, Lee CR, Chun JN, Cho NH, Kim IG, Lee S, Kim TW, Park HH, So I, Jeon JH.
    Int J Oncol; 2012 May 15; 40(5):1683-90. PubMed ID: 22200837
    [Abstract] [Full Text] [Related]

  • 6. Benzyl isothiocyanate induces reactive oxygen species-initiated autophagy and apoptosis in human prostate cancer cells.
    Lin JF, Tsai TF, Yang SC, Lin YC, Chen HE, Chou KY, Hwang TI.
    Oncotarget; 2017 Mar 21; 8(12):20220-20234. PubMed ID: 28423628
    [Abstract] [Full Text] [Related]

  • 7. Benzyl isothiocyanate (BITC) induces G2/M phase arrest and apoptosis in human melanoma A375.S2 cells through reactive oxygen species (ROS) and both mitochondria-dependent and death receptor-mediated multiple signaling pathways.
    Huang SH, Wu LW, Huang AC, Yu CC, Lien JC, Huang YP, Yang JS, Yang JH, Hsiao YP, Wood WG, Yu CS, Chung JG.
    J Agric Food Chem; 2012 Jan 18; 60(2):665-75. PubMed ID: 22148415
    [Abstract] [Full Text] [Related]

  • 8. Benzyl isothiocyanate (BITC) induces apoptosis in ovarian cancer cells in vitro.
    Kalkunte S, Swamy N, Dizon DS, Brard L.
    J Exp Ther Oncol; 2006 Jan 18; 5(4):287-300. PubMed ID: 17024969
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of nuclear factor kappaB activation in PC3 cells by genistein is mediated via Akt signaling pathway.
    Li Y, Sarkar FH.
    Clin Cancer Res; 2002 Jul 18; 8(7):2369-77. PubMed ID: 12114442
    [Abstract] [Full Text] [Related]

  • 10. mTOR is a fine tuning molecule in CDK inhibitors-induced distinct cell death mechanisms via PI3K/AKT/mTOR signaling axis in prostate cancer cells.
    Berrak O, Arisan ED, Obakan-Yerlikaya P, Coker-Gürkan A, Palavan-Unsal N.
    Apoptosis; 2016 Oct 18; 21(10):1158-78. PubMed ID: 27484210
    [Abstract] [Full Text] [Related]

  • 11. Inhibition of mTOR activity restores tamoxifen response in breast cancer cells with aberrant Akt Activity.
    deGraffenried LA, Friedrichs WE, Russell DH, Donzis EJ, Middleton AK, Silva JM, Roth RA, Hidalgo M.
    Clin Cancer Res; 2004 Dec 01; 10(23):8059-67. PubMed ID: 15585641
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  • 12. Enhanced expression of glucose transporter-1 in vascular smooth muscle cells via the Akt/tuberous sclerosis complex subunit 2 (TSC2)/mammalian target of rapamycin (mTOR)/ribosomal S6 protein kinase (S6K) pathway in experimental renal failure.
    Lin CY, Hsu SC, Lee HS, Lin SH, Tsai CS, Huang SM, Shih CC, Hsu YJ.
    J Vasc Surg; 2013 Feb 01; 57(2):475-85. PubMed ID: 23265586
    [Abstract] [Full Text] [Related]

  • 13. Benzyl isothiocyanate (BITC) and phenethyl isothiocyanate (PEITC)-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of caspase-3, mitochondria dysfunction and nitric oxide (NO) in human osteogenic sarcoma U-2 OS cells.
    Wu CL, Huang AC, Yang JS, Liao CL, Lu HF, Chou ST, Ma CY, Hsia TC, Ko YC, Chung JG.
    J Orthop Res; 2011 Aug 01; 29(8):1199-209. PubMed ID: 21374707
    [Abstract] [Full Text] [Related]

  • 14. AKT is involved in granulosa cell autophagy regulation via mTOR signaling during rat follicular development and atresia.
    Choi J, Jo M, Lee E, Choi D.
    Reproduction; 2014 Jan 01; 147(1):73-80. PubMed ID: 24131573
    [Abstract] [Full Text] [Related]

  • 15. mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways.
    Majumder PK, Febbo PG, Bikoff R, Berger R, Xue Q, McMahon LM, Manola J, Brugarolas J, McDonnell TJ, Golub TR, Loda M, Lane HA, Sellers WR.
    Nat Med; 2004 Jun 01; 10(6):594-601. PubMed ID: 15156201
    [Abstract] [Full Text] [Related]

  • 16. Autophagy Induction by α-Santalol in Human Prostate Cancer Cells.
    Walters C, Reed M, Bartholomew S, Bommareddy A.
    Anticancer Res; 2021 Mar 01; 41(3):1197-1202. PubMed ID: 33788710
    [Abstract] [Full Text] [Related]

  • 17. HS-116, a novel phosphatidylinositol 3-kinase inhibitor induces apoptosis and suppresses angiogenesis of hepatocellular carcinoma through inhibition of the PI3K/AKT/mTOR pathway.
    Jung KH, Choi MJ, Hong S, Lee H, Hong SW, Zheng HM, Lee HS, Hong S, Hong SS.
    Cancer Lett; 2012 Mar 28; 316(2):187-95. PubMed ID: 22182943
    [Abstract] [Full Text] [Related]

  • 18. Monascuspiloin induces apoptosis and autophagic cell death in human prostate cancer cells via the Akt and AMPK signaling pathways.
    Chen RJ, Hung CM, Chen YL, Wu MD, Yuan GF, Wang YJ.
    J Agric Food Chem; 2012 Jul 25; 60(29):7185-93. PubMed ID: 22738037
    [Abstract] [Full Text] [Related]

  • 19. Antitumor activity of curcumin by modulation of apoptosis and autophagy in human lung cancer A549 cells through inhibiting PI3K/Akt/mTOR pathway.
    Liu F, Gao S, Yang Y, Zhao X, Fan Y, Ma W, Yang D, Yang A, Yu Y.
    Oncol Rep; 2018 Mar 25; 39(3):1523-1531. PubMed ID: 29328421
    [Abstract] [Full Text] [Related]

  • 20. Licochalcone A induces autophagy through PI3K/Akt/mTOR inactivation and autophagy suppression enhances Licochalcone A-induced apoptosis of human cervical cancer cells.
    Tsai JP, Lee CH, Ying TH, Lin CL, Lin CL, Hsueh JT, Hsieh YH.
    Oncotarget; 2015 Oct 06; 6(30):28851-66. PubMed ID: 26311737
    [Abstract] [Full Text] [Related]

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