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Journal Abstract Search

133 related items for PubMed ID: 23181574

  • 1.
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  • 2. Inhibition of NEDD8-conjugation pathway by novel molecules: potential approaches to anticancer therapy.
    Tanaka T, Nakatani T, Kamitani T.
    Mol Oncol; 2012 Jun; 6(3):267-75. PubMed ID: 22306028
    [Abstract] [Full Text] [Related]

  • 3. MLN4924: a novel first-in-class inhibitor of NEDD8-activating enzyme for cancer therapy.
    Nawrocki ST, Griffin P, Kelly KR, Carew JS.
    Expert Opin Investig Drugs; 2012 Oct; 21(10):1563-73. PubMed ID: 22799561
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  • 5. Inhibition of NEDD8 and FAT10 ligase activities through the degrading enzyme NEDD8 ultimate buster 1: A potential anticancer approach.
    Tan KL, Pezzella F.
    Oncol Lett; 2016 Dec; 12(6):4287-4296. PubMed ID: 28101194
    [Abstract] [Full Text] [Related]

  • 6. Inactivation of the Cullin (CUL)-RING E3 ligase by the NEDD8-activating enzyme inhibitor MLN4924 triggers protective autophagy in cancer cells.
    Luo Z, Pan Y, Jeong LS, Liu J, Jia L.
    Autophagy; 2012 Nov; 8(11):1677-9. PubMed ID: 22874562
    [Abstract] [Full Text] [Related]

  • 7. Overactivated neddylation pathway as a therapeutic target in lung cancer.
    Li L, Wang M, Yu G, Chen P, Li H, Wei D, Zhu J, Xie L, Jia H, Shi J, Li C, Yao W, Wang Y, Gao Q, Jeong LS, Lee HW, Yu J, Hu F, Mei J, Wang P, Chu Y, Qi H, Yang M, Dong Z, Sun Y, Hoffman RM, Jia L.
    J Natl Cancer Inst; 2014 Jun; 106(6):dju083. PubMed ID: 24853380
    [Abstract] [Full Text] [Related]

  • 8. The steady-state repertoire of human SCF ubiquitin ligase complexes does not require ongoing Nedd8 conjugation.
    Lee JE, Sweredoski MJ, Graham RL, Kolawa NJ, Smith GT, Hess S, Deshaies RJ.
    Mol Cell Proteomics; 2011 May; 10(5):M110.006460. PubMed ID: 21169563
    [Abstract] [Full Text] [Related]

  • 9. NEDD8 ultimate buster-1 long (NUB1L) protein promotes transfer of NEDD8 to proteasome for degradation through the P97UFD1/NPL4 complex.
    Liu S, Yang H, Zhao J, Zhang YH, Song AX, Hu HY.
    J Biol Chem; 2013 Oct 25; 288(43):31339-49. PubMed ID: 24019527
    [Abstract] [Full Text] [Related]

  • 10. The Proteasome Lid Triggers COP9 Signalosome Activity during the Transition of Saccharomyces cerevisiae Cells into Quiescence.
    Bramasole L, Sinha A, Harshuk D, Cirigliano A, Gurevich S, Yu Z, Carmeli RL, Glickman MH, Rinaldi T, Pick E.
    Biomolecules; 2019 Sep 04; 9(9):. PubMed ID: 31487956
    [Abstract] [Full Text] [Related]

  • 11. Nedd8-modification of Cul1 is promoted by Roc1 as a Nedd8-E3 ligase and regulates its stability.
    Morimoto M, Nishida T, Nagayama Y, Yasuda H.
    Biochem Biophys Res Commun; 2003 Feb 07; 301(2):392-8. PubMed ID: 12565873
    [Abstract] [Full Text] [Related]

  • 12. Suppression of glioblastoma by targeting the overactivated protein neddylation pathway.
    Hua W, Li C, Yang Z, Li L, Jiang Y, Yu G, Zhu W, Liu Z, Duan S, Chu Y, Yang M, Zhang Y, Mao Y, Jia L.
    Neuro Oncol; 2015 Oct 07; 17(10):1333-43. PubMed ID: 25904638
    [Abstract] [Full Text] [Related]

  • 13. Biochemical and cellular effects of inhibiting Nedd8 conjugation.
    Leck YC, Choo YY, Tan CY, Smith PG, Hagen T.
    Biochem Biophys Res Commun; 2010 Jul 30; 398(3):588-93. PubMed ID: 20603103
    [Abstract] [Full Text] [Related]

  • 14. NEDD8 Inhibition Overcomes CKS1B-Induced Drug Resistance by Upregulation of p21 in Multiple Myeloma.
    Huang J, Zhou Y, Thomas GS, Gu Z, Yang Y, Xu H, Tricot G, Zhan F.
    Clin Cancer Res; 2015 Dec 15; 21(24):5532-42. PubMed ID: 26156395
    [Abstract] [Full Text] [Related]

  • 15. Regulation of neddylation and deneddylation of cullin1 in SCFSkp2 ubiquitin ligase by F-box protein and substrate.
    Bornstein G, Ganoth D, Hershko A.
    Proc Natl Acad Sci U S A; 2006 Aug 01; 103(31):11515-20. PubMed ID: 16861300
    [Abstract] [Full Text] [Related]

  • 16. Radiosensitization of human pancreatic cancer cells by MLN4924, an investigational NEDD8-activating enzyme inhibitor.
    Wei D, Li H, Yu J, Sebolt JT, Zhao L, Lawrence TS, Smith PG, Morgan MA, Sun Y.
    Cancer Res; 2012 Jan 01; 72(1):282-93. PubMed ID: 22072567
    [Abstract] [Full Text] [Related]

  • 17. Control of cullin-ring ubiquitin ligase activity by nedd8.
    Deshaies RJ, Emberley ED, Saha A.
    Subcell Biochem; 2010 Jan 01; 54():41-56. PubMed ID: 21222272
    [Abstract] [Full Text] [Related]

  • 18. Validation of NEDD8-conjugating enzyme UBC12 as a new therapeutic target in lung cancer.
    Li L, Kang J, Zhang W, Cai L, Wang S, Liang Y, Jiang Y, Liu X, Zhang Y, Ruan H, Chen G, Wang M, Jia L.
    EBioMedicine; 2019 Jul 01; 45():81-91. PubMed ID: 31208947
    [Abstract] [Full Text] [Related]

  • 19. An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer.
    Soucy TA, Smith PG, Milhollen MA, Berger AJ, Gavin JM, Adhikari S, Brownell JE, Burke KE, Cardin DP, Critchley S, Cullis CA, Doucette A, Garnsey JJ, Gaulin JL, Gershman RE, Lublinsky AR, McDonald A, Mizutani H, Narayanan U, Olhava EJ, Peluso S, Rezaei M, Sintchak MD, Talreja T, Thomas MP, Traore T, Vyskocil S, Weatherhead GS, Yu J, Zhang J, Dick LR, Claiborne CF, Rolfe M, Bolen JB, Langston SP.
    Nature; 2009 Apr 09; 458(7239):732-6. PubMed ID: 19360080
    [Abstract] [Full Text] [Related]

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