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Journal Abstract Search

139 related items for PubMed ID: 2318819

  • 1. A specific enhancing effect of N,N-dimethylsphingosine on epidermal growth factor receptor autophosphorylation. Demonstration of its endogenous occurrence (and the virtual absence of unsubstituted sphingosine) in human epidermoid carcinoma A431 cells.
    Igarashi Y, Kitamura K, Toyokuni T, Dean B, Fenderson B, Ogawass T, Hakomori S.
    J Biol Chem; 1990 Apr 05; 265(10):5385-9. PubMed ID: 2318819
    [Abstract] [Full Text] [Related]

  • 2. Effects of gangliosides GM3 and De-N-acetyl GM3 on epidermal growth factor receptor kinase activity and cell growth.
    Song WX, Vacca MF, Welti R, Rintoul DA.
    J Biol Chem; 1991 Jun 05; 266(16):10174-81. PubMed ID: 1645342
    [Abstract] [Full Text] [Related]

  • 3. Ceramide stimulates epidermal growth factor receptor phosphorylation in A431 human epidermoid carcinoma cells. Evidence that ceramide may mediate sphingosine action.
    Goldkorn T, Dressler KA, Muindi J, Radin NS, Mendelsohn J, Menaldino D, Liotta D, Kolesnick RN.
    J Biol Chem; 1991 Aug 25; 266(24):16092-7. PubMed ID: 1874747
    [Abstract] [Full Text] [Related]

  • 4. Cell membrane signaling as target in cancer therapy: inhibitory effect of N,N-dimethyl and N,N,N-trimethyl sphingosine derivatives on in vitro and in vivo growth of human tumor cells in nude mice.
    Endo K, Igarashi Y, Nisar M, Zhou QH, Hakomori S.
    Cancer Res; 1991 Mar 15; 51(6):1613-8. PubMed ID: 1998952
    [Abstract] [Full Text] [Related]

  • 5. Regulation of the epidermal growth factor receptor phosphorylation state by sphingosine in A431 human epidermoid carcinoma cells.
    Faucher M, Gironès N, Hannun YA, Bell RM, Davis RJ.
    J Biol Chem; 1988 Apr 15; 263(11):5319-27. PubMed ID: 3162730
    [Abstract] [Full Text] [Related]

  • 6. GM3 directly inhibits tyrosine phosphorylation and de-N-acetyl-GM3 directly enhances serine phosphorylation of epidermal growth factor receptor, independently of receptor-receptor interaction.
    Zhou Q, Hakomori S, Kitamura K, Igarashi Y.
    J Biol Chem; 1994 Jan 21; 269(3):1959-65. PubMed ID: 7507488
    [Abstract] [Full Text] [Related]

  • 7. Ganglioside-mediated modulation of cell growth. Specific effects of GM3 and lyso-GM3 in tyrosine phosphorylation of the epidermal growth factor receptor.
    Hanai N, Nores GA, MacLeod C, Torres-Mendez CR, Hakomori S.
    J Biol Chem; 1988 Aug 05; 263(22):10915-21. PubMed ID: 2839511
    [Abstract] [Full Text] [Related]

  • 8. Modulation by sphingolipids of calcium signals evoked by epidermal growth factor.
    Hudson PL, Pedersen WA, Saltsman WS, Liscovitch M, MacLaughlin DT, Donahoe PK, Blusztajn JK.
    J Biol Chem; 1994 Aug 26; 269(34):21885-90. PubMed ID: 8063833
    [Abstract] [Full Text] [Related]

  • 9. A ceramide analogue inhibits T cell proliferative response through inhibition of glycosphingolipid synthesis and enhancement of N,N-dimethylsphingosine synthesis.
    Felding-Habermann B, Igarashi Y, Fenderson BA, Park LS, Radin NS, Inokuchi J, Strassmann G, Handa K, Hakomori S.
    Biochemistry; 1990 Jul 03; 29(26):6314-22. PubMed ID: 2207076
    [Abstract] [Full Text] [Related]

  • 10. Ganglioside-mediated modulation of cell growth. Specific effects of GM3 on tyrosine phosphorylation of the epidermal growth factor receptor.
    Bremer EG, Schlessinger J, Hakomori S.
    J Biol Chem; 1986 Feb 15; 261(5):2434-40. PubMed ID: 2418024
    [Abstract] [Full Text] [Related]

  • 11. A431 cell variants lacking the blood group A antigen display increased high affinity epidermal growth factor-receptor number, protein-tyrosine kinase activity, and receptor turnover.
    Defize LH, Arndt-Jovin DJ, Jovin TM, Boonstra J, Meisenhelder J, Hunter T, de Hey HT, de Laat SW.
    J Cell Biol; 1988 Sep 15; 107(3):939-49. PubMed ID: 2458364
    [Abstract] [Full Text] [Related]

  • 12. In vitro and in vivo induction of apoptosis by sphingosine and N, N-dimethylsphingosine in human epidermoid carcinoma KB-3-1 and its multidrug-resistant cells.
    Shirahama T, Sweeney EA, Sakakura C, Singhal AK, Nishiyama K, Akiyama S, Hakomori S, Igarashi Y.
    Clin Cancer Res; 1997 Feb 15; 3(2):257-64. PubMed ID: 9815681
    [Abstract] [Full Text] [Related]

  • 13. cAMP-mediated modulation of signal transduction of epidermal growth factor (EGF) receptor systems in human epidermoid carcinoma A431 cells. Depression of EGF-dependent diacylglycerol production and EGF receptor phosphorylation.
    Iwashita S, Mitsui K, Shoji-Kasai Y, Senshu-Miyaike M.
    J Biol Chem; 1990 Jun 25; 265(18):10702-8. PubMed ID: 1693923
    [Abstract] [Full Text] [Related]

  • 14. Glucosylceramide synthase inhibitor inhibits the action of nerve growth factor in PC12 cells.
    Mutoh T, Tokuda A, Inokuchi J, Kuriyama M.
    J Biol Chem; 1998 Oct 02; 273(40):26001-7. PubMed ID: 9748278
    [Abstract] [Full Text] [Related]

  • 15. Effect of lipid mimetics of GM3 and lyso-GM3 dimer on EGF receptor tyrosine kinase and EGF-induced signal transduction.
    Haga Y, Hatanaka K, Hakomori SI.
    Biochim Biophys Acta; 2008 Mar 02; 1780(3):393-404. PubMed ID: 18036568
    [Abstract] [Full Text] [Related]

  • 16. The rise and fall of ceramide and 1,2-diacylglycerol (DAG): modulation by transforming growth factor-beta 1 (TGF beta 1) and by epidermal growth factor (EGF).
    Goldkorn T, Ding T.
    Adv Exp Med Biol; 1997 Mar 02; 400A():461-72. PubMed ID: 9547591
    [Abstract] [Full Text] [Related]

  • 17. Divergence in signal transduction pathways of platelet-derived growth factor (PDGF) and epidermal growth factor (EGF) receptors. Involvement of sphingosine 1-phosphate in PDGF but not EGF signaling.
    Rani CS, Wang F, Fuior E, Berger A, Wu J, Sturgill TW, Beitner-Johnson D, LeRoith D, Varticovski L, Spiegel S.
    J Biol Chem; 1997 Apr 18; 272(16):10777-83. PubMed ID: 9099730
    [Abstract] [Full Text] [Related]

  • 18. A novel sphingosine-dependent protein kinase (SDK1) specifically phosphorylates certain isoforms of 14-3-3 protein.
    Megidish T, Cooper J, Zhang L, Fu H, Hakomori S.
    J Biol Chem; 1998 Aug 21; 273(34):21834-45. PubMed ID: 9705322
    [Abstract] [Full Text] [Related]

  • 19. Cytoskeletal and morphological changes associated with the specific suppression of the epidermal growth factor receptor tyrosine kinase activity in A431 human epidermoid carcinoma.
    Nelson JM, Fry DW.
    Exp Cell Res; 1997 Jun 15; 233(2):383-90. PubMed ID: 9194500
    [Abstract] [Full Text] [Related]

  • 20. A role of lyso-phosphatidylcholine in GM3-dependent inhibition of epidermal growth factor receptor autophosphorylation in A431 plasma membranes.
    Igarashi Y, Kitamura K, Zhou QH, Hakomori S.
    Biochem Biophys Res Commun; 1990 Oct 15; 172(1):77-84. PubMed ID: 2171524
    [Abstract] [Full Text] [Related]

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