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Journal Abstract Search

282 related items for PubMed ID: 23208311

  • 1. Morphogen pathways as molecular targets for the treatment of fibrosis in systemic sclerosis.
    Beyer C, Dees C, Distler JH.
    Arch Dermatol Res; 2013 Jan; 305(1):1-8. PubMed ID: 23208311
    [Abstract] [Full Text] [Related]

  • 2. Combined inhibition of morphogen pathways demonstrates additive antifibrotic effects and improved tolerability.
    Distler A, Lang V, Del Vecchio T, Huang J, Zhang Y, Beyer C, Lin NY, Palumbo-Zerr K, Distler O, Schett G, Distler JH.
    Ann Rheum Dis; 2014 Jun; 73(6):1264-8. PubMed ID: 24445254
    [Abstract] [Full Text] [Related]

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    [No Abstract] [Full Text] [Related]

  • 4. Canonical Wnt signalling as a key regulator of fibrogenesis - implications for targeted therapies?
    Dees C, Distler JH.
    Exp Dermatol; 2013 Nov; 22(11):710-3. PubMed ID: 24118232
    [Abstract] [Full Text] [Related]

  • 5. Hedgehog signaling controls fibroblast activation and tissue fibrosis in systemic sclerosis.
    Horn A, Palumbo K, Cordazzo C, Dees C, Akhmetshina A, Tomcik M, Zerr P, Avouac J, Gusinde J, Zwerina J, Roudaut H, Traiffort E, Ruat M, Distler O, Schett G, Distler JH.
    Arthritis Rheum; 2012 Aug; 64(8):2724-33. PubMed ID: 22354771
    [Abstract] [Full Text] [Related]

  • 6. Inactivation of tankyrases reduces experimental fibrosis by inhibiting canonical Wnt signalling.
    Distler A, Deloch L, Huang J, Dees C, Lin NY, Palumbo-Zerr K, Beyer C, Weidemann A, Distler O, Schett G, Distler JH.
    Ann Rheum Dis; 2013 Sep 01; 72(9):1575-80. PubMed ID: 23148305
    [Abstract] [Full Text] [Related]

  • 7. Notch signalling regulates fibroblast activation and collagen release in systemic sclerosis.
    Dees C, Tomcik M, Zerr P, Akhmetshina A, Horn A, Palumbo K, Beyer C, Zwerina J, Distler O, Schett G, Distler JH.
    Ann Rheum Dis; 2011 Jul 01; 70(7):1304-10. PubMed ID: 21450749
    [Abstract] [Full Text] [Related]

  • 8. Inhibition of Notch signaling prevents experimental fibrosis and induces regression of established fibrosis.
    Dees C, Zerr P, Tomcik M, Beyer C, Horn A, Akhmetshina A, Palumbo K, Reich N, Zwerina J, Sticherling M, Mattson MP, Distler O, Schett G, Distler JH.
    Arthritis Rheum; 2011 May 01; 63(5):1396-404. PubMed ID: 21312186
    [Abstract] [Full Text] [Related]

  • 9. Long non-coding RNA HOTAIR drives EZH2-dependent myofibroblast activation in systemic sclerosis through miRNA 34a-dependent activation of NOTCH.
    Wasson CW, Abignano G, Hermes H, Malaab M, Ross RL, Jimenez SA, Chang HY, Feghali-Bostwick CA, Del Galdo F.
    Ann Rheum Dis; 2020 Apr 01; 79(4):507-517. PubMed ID: 32041748
    [Abstract] [Full Text] [Related]

  • 10. Long non-coding RNA HOTAIR induces GLI2 expression through Notch signalling in systemic sclerosis dermal fibroblasts.
    Wasson CW, Ross RL, Wells R, Corinaldesi C, Georgiou IC, Riobo-Del Galdo NA, Del Galdo F.
    Arthritis Res Ther; 2020 Dec 10; 22(1):286. PubMed ID: 33303026
    [Abstract] [Full Text] [Related]

  • 11. Anti-fibrotic effects of pirfenidone by interference with the hedgehog signalling pathway in patients with systemic sclerosis-associated interstitial lung disease.
    Xiao H, Zhang GF, Liao XP, Li XJ, Zhang J, Lin H, Chen Z, Zhang X.
    Int J Rheum Dis; 2018 Feb 10; 21(2):477-486. PubMed ID: 29316328
    [Abstract] [Full Text] [Related]

  • 12. Developmental signalling pathways in renal fibrosis: the roles of Notch, Wnt and Hedgehog.
    Edeling M, Ragi G, Huang S, Pavenstädt H, Susztak K.
    Nat Rev Nephrol; 2016 Jul 10; 12(7):426-39. PubMed ID: 27140856
    [Abstract] [Full Text] [Related]

  • 13. β-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis.
    Beyer C, Schramm A, Akhmetshina A, Dees C, Kireva T, Gelse K, Sonnylal S, de Crombrugghe B, Taketo MM, Distler O, Schett G, Distler JH.
    Ann Rheum Dis; 2012 May 10; 71(5):761-7. PubMed ID: 22328737
    [Abstract] [Full Text] [Related]

  • 14. Pharmacological inhibition of porcupine induces regression of experimental skin fibrosis by targeting Wnt signalling.
    Chen CW, Beyer C, Liu J, Maier C, Li C, Trinh-Minh T, Xu X, Cole SH, Hsieh MH, Ng N, Althage A, Meeusen S, Pan S, Svensson EC, Seidel HM, Schett G, Gergely P, Harris JL, Distler JH.
    Ann Rheum Dis; 2017 Apr 10; 76(4):773-778. PubMed ID: 28153829
    [Abstract] [Full Text] [Related]

  • 15. Evolving insights into the cellular and molecular pathogenesis of fibrosis in systemic sclerosis.
    Korman B.
    Transl Res; 2019 Jul 10; 209():77-89. PubMed ID: 30876809
    [Abstract] [Full Text] [Related]

  • 16. Inhibition of glycogen synthase kinase 3β induces dermal fibrosis by activation of the canonical Wnt pathway.
    Bergmann C, Akhmetshina A, Dees C, Palumbo K, Zerr P, Beyer C, Zwerina J, Distler O, Schett G, Distler JH.
    Ann Rheum Dis; 2011 Dec 10; 70(12):2191-8. PubMed ID: 21873331
    [Abstract] [Full Text] [Related]

  • 17. Matrix Stiffness: the Conductor of Organ Fibrosis.
    Santos A, Lagares D.
    Curr Rheumatol Rep; 2018 Jan 19; 20(1):2. PubMed ID: 29349703
    [Abstract] [Full Text] [Related]

  • 18. Doubling down with inhibitors of Notch and Hedgehog signaling pathways.
    Weiss GJ.
    J Thorac Oncol; 2012 Dec 19; 7(16 Suppl 5):S409-10. PubMed ID: 23160337
    [No Abstract] [Full Text] [Related]

  • 19. Therapeutic target discovery and drug development in cancer stem cells for leukemia and lymphoma: from bench to the clinic.
    Laranjeira AB, Yang SX.
    Expert Opin Drug Discov; 2016 Nov 19; 11(11):1071-1080. PubMed ID: 27626707
    [Abstract] [Full Text] [Related]

  • 20. Fibrosis in systemic sclerosis: emerging concepts and implications for targeted therapy.
    Wei J, Bhattacharyya S, Tourtellotte WG, Varga J.
    Autoimmun Rev; 2011 Mar 19; 10(5):267-75. PubMed ID: 20863909
    [Abstract] [Full Text] [Related]

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