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163 related items for PubMed ID: 2321166

  • 1. Relationship of DNA damage and embryotoxicity induced by 4-hydroperoxydechlorocyclophosphamide in postimplantation rat embryos.
    Little SA, Mirkes PE.
    Teratology; 1990 Feb; 41(2):223-31. PubMed ID: 2321166
    [Abstract] [Full Text] [Related]

  • 2. Effects of 4-hydroperoxycyclophosphamide (4-OOH-CP) and 4-hydroperoxydechlorocyclophosphamide (4-OOH-deCICP) on the cell cycle of post implantation rat embryos.
    Little SA, Mirkes PE.
    Teratology; 1992 Feb; 45(2):163-73. PubMed ID: 1615426
    [Abstract] [Full Text] [Related]

  • 3. Enhancement of the embryotoxicity of acrolein, but not phosphoramide mustard, by glutathione depletion in rat embryos in vitro.
    Slott VL, Hales BF.
    Biochem Pharmacol; 1987 Jun 15; 36(12):2019-25. PubMed ID: 3593406
    [Abstract] [Full Text] [Related]

  • 4. Role of acrolein in cyclophosphamide teratogenicity in rat embryos in vitro.
    Mirkes PE, Greenaway JC, Rogers JG, Brundrett RB.
    Toxicol Appl Pharmacol; 1984 Feb 15; 72(2):281-91. PubMed ID: 6546458
    [Abstract] [Full Text] [Related]

  • 5. Role of apoptosis in mediating phosphoramide mustard-induced rat embryo malformations in vitro.
    Chen B, Cyr DG, Hales BF.
    Teratology; 1994 Jul 15; 50(1):1-12. PubMed ID: 7974249
    [Abstract] [Full Text] [Related]

  • 6. Glutathione depletion as a determinant of sensitivity of human leukemia cells to cyclophosphamide.
    Crook TR, Souhami RL, Whyman GD, McLean AE.
    Cancer Res; 1986 Oct 15; 46(10):5035-8. PubMed ID: 3463410
    [Abstract] [Full Text] [Related]

  • 7. Cytotoxicity, DNA cross-linking, and single strand breaks induced by activated cyclophosphamide and acrolein in human leukemia cells.
    Crook TR, Souhami RL, McLean AE.
    Cancer Res; 1986 Oct 15; 46(10):5029-34. PubMed ID: 3463409
    [Abstract] [Full Text] [Related]

  • 8. Morphological and biochemical aspects of monofunctional phosphoramide mustard teratogenicity in rat embryos cultured in vitro.
    Mirkes PE, Greenaway JC, Hilton J, Brundrett R.
    Teratology; 1985 Oct 15; 32(2):241-9. PubMed ID: 4049282
    [Abstract] [Full Text] [Related]

  • 9. DNA cross-linking and single-strand breaks induced by teratogenic concentrations of 4-hydroperoxycyclophosphamide and phosphoramide mustard in postimplantation rat embryos.
    Little SA, Mirkes PE.
    Cancer Res; 1987 Oct 15; 47(20):5421-6. PubMed ID: 3477317
    [Abstract] [Full Text] [Related]

  • 10. Embryotoxicity of phenyl ketone analogs of cyclophosphamide.
    Hales BF, Ludeman SM, Boyd VL.
    Teratology; 1989 Jan 15; 39(1):31-7. PubMed ID: 2718138
    [Abstract] [Full Text] [Related]

  • 11. Effect of acrolein on phosphoramide mustard-induced sister chromatid exchanges in cultured human lymphocytes.
    Wilmer JL, Erexson GL, Kligerman AD.
    Cancer Res; 1990 Aug 01; 50(15):4635-8. PubMed ID: 2369740
    [Abstract] [Full Text] [Related]

  • 12. Protection of rat embryos in culture against the embryotoxicity of acrolein using exogenous glutathione.
    Slott VL, Hales BF.
    Biochem Pharmacol; 1987 Jul 01; 36(13):2187-94. PubMed ID: 3606635
    [Abstract] [Full Text] [Related]

  • 13. Investigation on cyclophosphamide treatment during the preimplantation period. II. In vitro studies on the effects of cyclophosphamide and its metabolites 4-OH-cyclophosphamide, phosphoramide mustard, and acrolein on blastulation of four-cell and eight-cell mouse embryos and on their subsequent development during implantation.
    Spielmann H, Jacob-Müller U.
    Teratology; 1981 Feb 01; 23(1):7-13. PubMed ID: 7245091
    [Abstract] [Full Text] [Related]

  • 14. The embryolethality and teratogenicity of acrolein in cultured rat embryos.
    Slott VL, Hales BF.
    Teratology; 1986 Oct 01; 34(2):155-63. PubMed ID: 3775668
    [Abstract] [Full Text] [Related]

  • 15. Cyclophosphamide modulates rat hepatic cytochrome P450 2C11 and steroid 5 alpha-reductase activity and messenger RNA levels through the combined action of acrolein and phosphoramide mustard.
    Chang TK, Waxman DJ.
    Cancer Res; 1993 Jun 01; 53(11):2490-7. PubMed ID: 8495410
    [Abstract] [Full Text] [Related]

  • 16. Effects of phosphoramide mustard and acrolein, cytotoxic metabolites of cyclophosphamide, on mouse limb development in vitro.
    Hales BF.
    Teratology; 1989 Jul 01; 40(1):11-20. PubMed ID: 2763206
    [Abstract] [Full Text] [Related]

  • 17. The effect of oxygen concentration on the teratogenicity of salicylate, niridazole, cyclophosphamide, and phosphoramide mustard in rat embryos in vitro.
    Greenaway JC, Mirkes PE, Walker EA, Juchau MR, Shepard TH, Fantel AG.
    Teratology; 1985 Oct 01; 32(2):287-95. PubMed ID: 4049287
    [Abstract] [Full Text] [Related]

  • 18. Attenuation of cytogenetic damage by 2-mercaptoethanesulfonate in cultured human lymphocytes exposed to cyclophosphamide and its reactive metabolites.
    Wilmer JL, Erexson GL, Kligerman AD.
    Cancer Res; 1986 Jan 01; 46(1):203-10. PubMed ID: 3079586
    [Abstract] [Full Text] [Related]

  • 19. The embryotoxicity of the cyclophosphamide metabolite acrolein in rabbits, tested in vivo by i.v. injection and by the yolk-sac method.
    Claussen U, Hellmann W, Pache G.
    Arzneimittelforschung; 1980 Jan 01; 30(12):2080-3. PubMed ID: 7194065
    [Abstract] [Full Text] [Related]

  • 20. Teratogenicity of cyclophosphamide metabolites: phosphoramide mustard, acrolein, and 4-ketocyclophosphamide in rat embryos cultured in vitro.
    Mirkes PE, Fantel AG, Greenaway JC, Shepard TH.
    Toxicol Appl Pharmacol; 1981 Apr 01; 58(2):322-30. PubMed ID: 7245204
    [No Abstract] [Full Text] [Related]

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