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552 related items for PubMed ID: 23213108

  • 1. Deranged myofilament phosphorylation and function in experimental heart failure with preserved ejection fraction.
    Hamdani N, Bishu KG, von Frieling-Salewsky M, Redfield MM, Linke WA.
    Cardiovasc Res; 2013 Mar 01; 97(3):464-71. PubMed ID: 23213108
    [Abstract] [Full Text] [Related]

  • 2. Protein kinase G modulates human myocardial passive stiffness by phosphorylation of the titin springs.
    Krüger M, Kötter S, Grützner A, Lang P, Andresen C, Redfield MM, Butt E, dos Remedios CG, Linke WA.
    Circ Res; 2009 Jan 02; 104(1):87-94. PubMed ID: 19023132
    [Abstract] [Full Text] [Related]

  • 3. Hypophosphorylation of the Stiff N2B titin isoform raises cardiomyocyte resting tension in failing human myocardium.
    Borbély A, Falcao-Pires I, van Heerebeek L, Hamdani N, Edes I, Gavina C, Leite-Moreira AF, Bronzwaer JG, Papp Z, van der Velden J, Stienen GJ, Paulus WJ.
    Circ Res; 2009 Mar 27; 104(6):780-6. PubMed ID: 19179657
    [Abstract] [Full Text] [Related]

  • 4. Differential changes in titin domain phosphorylation increase myofilament stiffness in failing human hearts.
    Kötter S, Gout L, Von Frieling-Salewsky M, Müller AE, Helling S, Marcus K, Dos Remedios C, Linke WA, Krüger M.
    Cardiovasc Res; 2013 Sep 01; 99(4):648-56. PubMed ID: 23764881
    [Abstract] [Full Text] [Related]

  • 5. Crucial role for Ca2(+)/calmodulin-dependent protein kinase-II in regulating diastolic stress of normal and failing hearts via titin phosphorylation.
    Hamdani N, Krysiak J, Kreusser MM, Neef S, Dos Remedios CG, Maier LS, Krüger M, Backs J, Linke WA.
    Circ Res; 2013 Feb 15; 112(4):664-74. PubMed ID: 23283722
    [Abstract] [Full Text] [Related]

  • 6. A novel paradigm for heart failure with preserved ejection fraction: comorbidities drive myocardial dysfunction and remodeling through coronary microvascular endothelial inflammation.
    Paulus WJ, Tschöpe C.
    J Am Coll Cardiol; 2013 Jul 23; 62(4):263-71. PubMed ID: 23684677
    [Abstract] [Full Text] [Related]

  • 7. Diabetes-Induced Cardiomyocyte Passive Stiffening Is Caused by Impaired Insulin-Dependent Titin Modification and Can Be Modulated by Neuregulin-1.
    Hopf AE, Andresen C, Kötter S, Isić M, Ulrich K, Sahin S, Bongardt S, Röll W, Drove F, Scheerer N, Vandekerckhove L, De Keulenaer GW, Hamdani N, Linke WA, Krüger M.
    Circ Res; 2018 Jul 20; 123(3):342-355. PubMed ID: 29760016
    [Abstract] [Full Text] [Related]

  • 8. Insulin signaling regulates cardiac titin properties in heart development and diabetic cardiomyopathy.
    Krüger M, Babicz K, von Frieling-Salewsky M, Linke WA.
    J Mol Cell Cardiol; 2010 May 20; 48(5):910-6. PubMed ID: 20184888
    [Abstract] [Full Text] [Related]

  • 9. Low myocardial protein kinase G activity in heart failure with preserved ejection fraction.
    van Heerebeek L, Hamdani N, Falcão-Pires I, Leite-Moreira AF, Begieneman MP, Bronzwaer JG, van der Velden J, Stienen GJ, Laarman GJ, Somsen A, Verheugt FW, Niessen HW, Paulus WJ.
    Circulation; 2012 Aug 14; 126(7):830-9. PubMed ID: 22806632
    [Abstract] [Full Text] [Related]

  • 10. Myocardial titin hypophosphorylation importantly contributes to heart failure with preserved ejection fraction in a rat metabolic risk model.
    Hamdani N, Franssen C, Lourenço A, Falcão-Pires I, Fontoura D, Leite S, Plettig L, López B, Ottenheijm CA, Becher PM, González A, Tschöpe C, Díez J, Linke WA, Leite-Moreira AF, Paulus WJ.
    Circ Heart Fail; 2013 Nov 14; 6(6):1239-49. PubMed ID: 24014826
    [Abstract] [Full Text] [Related]

  • 11. Prevention of myofilament dysfunction by beta-blocker therapy in postinfarct remodeling.
    Duncker DJ, Boontje NM, Merkus D, Versteilen A, Krysiak J, Mearini G, El-Armouche A, de Beer VJ, Lamers JM, Carrier L, Walker LA, Linke WA, Stienen GJ, van der Velden J.
    Circ Heart Fail; 2009 May 14; 2(3):233-42. PubMed ID: 19808345
    [Abstract] [Full Text] [Related]

  • 12. Myocardial stiffness in patients with heart failure and a preserved ejection fraction: contributions of collagen and titin.
    Zile MR, Baicu CF, Ikonomidis JS, Stroud RE, Nietert PJ, Bradshaw AD, Slater R, Palmer BM, Van Buren P, Meyer M, Redfield MM, Bull DA, Granzier HL, LeWinter MM.
    Circulation; 2015 Apr 07; 131(14):1247-59. PubMed ID: 25637629
    [Abstract] [Full Text] [Related]

  • 13. Protein kinase-A phosphorylates titin in human heart muscle and reduces myofibrillar passive tension.
    Krüger M, Linke WA.
    J Muscle Res Cell Motil; 2006 Apr 07; 27(5-7):435-44. PubMed ID: 16897574
    [Abstract] [Full Text] [Related]

  • 14. Sex-specific cardiovascular remodeling leads to a divergent sex-dependent development of heart failure in aged hypertensive rats.
    Kovács Á, Zhazykbayeva S, Herwig M, Fülöp GÁ, Csípő T, Oláh N, Hassoun R, Budde H, Osman H, Kaçmaz M, Jaquet K, Priksz D, Juhász B, Akin I, Papp Z, Schmidt WE, Mügge A, El-Battrawy I, Tóth A, Hamdani N.
    Geroscience; 2024 Oct 07; 46(5):4543-4561. PubMed ID: 38656649
    [Abstract] [Full Text] [Related]

  • 15. Elastic titin properties and protein quality control in the aging heart.
    Salcan S, Bongardt S, Monteiro Barbosa D, Efimov IR, Rassaf T, Krüger M, Kötter S.
    Biochim Biophys Acta Mol Cell Res; 2020 Mar 07; 1867(3):118532. PubMed ID: 31421188
    [Abstract] [Full Text] [Related]

  • 16. Metformin improves diastolic function in an HFpEF-like mouse model by increasing titin compliance.
    Slater RE, Strom JG, Methawasin M, Liss M, Gotthardt M, Sweitzer N, Granzier HL.
    J Gen Physiol; 2019 Jan 07; 151(1):42-52. PubMed ID: 30567709
    [Abstract] [Full Text] [Related]

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  • 19. Cardiomyocyte stiffness in diastolic heart failure.
    Borbély A, van der Velden J, Papp Z, Bronzwaer JG, Edes I, Stienen GJ, Paulus WJ.
    Circulation; 2005 Feb 15; 111(6):774-81. PubMed ID: 15699264
    [Abstract] [Full Text] [Related]

  • 20. Experimentally Increasing the Compliance of Titin Through RNA Binding Motif-20 (RBM20) Inhibition Improves Diastolic Function In a Mouse Model of Heart Failure With Preserved Ejection Fraction.
    Methawasin M, Strom JG, Slater RE, Fernandez V, Saripalli C, Granzier H.
    Circulation; 2016 Oct 11; 134(15):1085-1099. PubMed ID: 27630136
    [Abstract] [Full Text] [Related]

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