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159 related items for PubMed ID: 23219469

  • 1. Direct transmembrane interaction between actin and the pore-competent, cholesterol-dependent cytolysin pneumolysin.
    Hupp S, Förtsch C, Wippel C, Ma J, Mitchell TJ, Iliev AI.
    J Mol Biol; 2013 Feb 08; 425(3):636-46. PubMed ID: 23219469
    [Abstract] [Full Text] [Related]

  • 2. Changes in astrocyte shape induced by sublytic concentrations of the cholesterol-dependent cytolysin pneumolysin still require pore-forming capacity.
    Förtsch C, Hupp S, Ma J, Mitchell TJ, Maier E, Benz R, Iliev AI.
    Toxins (Basel); 2011 Jan 08; 3(1):43-62. PubMed ID: 22069689
    [Abstract] [Full Text] [Related]

  • 3. The cholesterol-dependent cytolysin pneumolysin from Streptococcus pneumoniae binds to lipid raft microdomains in human corneal epithelial cells.
    Taylor SD, Sanders ME, Tullos NA, Stray SJ, Norcross EW, McDaniel LS, Marquart ME.
    PLoS One; 2013 Jan 08; 8(4):e61300. PubMed ID: 23577214
    [Abstract] [Full Text] [Related]

  • 4. Pneumolysin: a double-edged sword during the host-pathogen interaction.
    Marriott HM, Mitchell TJ, Dockrell DH.
    Curr Mol Med; 2008 Sep 08; 8(6):497-509. PubMed ID: 18781957
    [Abstract] [Full Text] [Related]

  • 5. Glucose and Oxygen Levels Modulate the Pore-Forming Effects of Cholesterol-Dependent Cytolysin Pneumolysin from Streptococcus pneumoniae.
    Hoffet MS, Tomov NS, Hupp S, Mitchell TJ, Iliev AI.
    Toxins (Basel); 2024 May 21; 16(6):. PubMed ID: 38922127
    [Abstract] [Full Text] [Related]

  • 6. Structural insights into loss of function of a pore forming toxin and its role in pneumococcal adaptation to an intracellular lifestyle.
    Badgujar DC, Anil A, Green AE, Surve MV, Madhavan S, Beckett A, Prior IA, Godsora BK, Patil SB, More PK, Sarkar SG, Mitchell A, Banerjee R, Phale PS, Mitchell TJ, Neill DR, Bhaumik P, Banerjee A.
    PLoS Pathog; 2020 Nov 21; 16(11):e1009016. PubMed ID: 33216805
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  • 7. Membrane perforation by the pore-forming toxin pneumolysin.
    Vögele M, Bhaskara RM, Mulvihill E, van Pee K, Yildiz Ö, Kühlbrandt W, Müller DJ, Hummer G.
    Proc Natl Acad Sci U S A; 2019 Jul 02; 116(27):13352-13357. PubMed ID: 31209022
    [Abstract] [Full Text] [Related]

  • 8. Bacterial cytolysin during meningitis disrupts the regulation of glutamate in the brain, leading to synaptic damage.
    Wippel C, Maurer J, Förtsch C, Hupp S, Bohl A, Ma J, Mitchell TJ, Bunkowski S, Brück W, Nau R, Iliev AI.
    PLoS Pathog; 2013 Jul 02; 9(6):e1003380. PubMed ID: 23785278
    [Abstract] [Full Text] [Related]

  • 9. Astrocytic tissue remodeling by the meningitis neurotoxin pneumolysin facilitates pathogen tissue penetration and produces interstitial brain edema.
    Hupp S, Heimeroth V, Wippel C, Förtsch C, Ma J, Mitchell TJ, Iliev AI.
    Glia; 2012 Jan 02; 60(1):137-46. PubMed ID: 21989652
    [Abstract] [Full Text] [Related]

  • 10. Pneumolysin localizes to the cell wall of Streptococcus pneumoniae.
    Price KE, Camilli A.
    J Bacteriol; 2009 Apr 02; 191(7):2163-8. PubMed ID: 19168620
    [Abstract] [Full Text] [Related]

  • 11. Acacetin inhibits Streptococcus pneumoniae virulence by targeting pneumolysin.
    Li S, Lv Q, Sun X, Tang T, Deng X, Yin Y, Li L.
    J Pharm Pharmacol; 2020 Aug 02; 72(8):1092-1100. PubMed ID: 32390150
    [Abstract] [Full Text] [Related]

  • 12. Rapid microtubule bundling and stabilization by the Streptococcus pneumoniae neurotoxin pneumolysin in a cholesterol-dependent, non-lytic and Src-kinase dependent manner inhibits intracellular trafficking.
    Iliev AI, Djannatian JR, Opazo F, Gerber J, Nau R, Mitchell TJ, Wouters FS.
    Mol Microbiol; 2009 Jan 02; 71(2):461-77. PubMed ID: 19040644
    [Abstract] [Full Text] [Related]

  • 13. Neuronal death in pneumococcal meningitis is triggered by pneumolysin and RrgA interactions with β-actin.
    Tabusi M, Thorsdottir S, Lysandrou M, Narciso AR, Minoia M, Srambickal CV, Widengren J, Henriques-Normark B, Iovino F.
    PLoS Pathog; 2021 Mar 02; 17(3):e1009432. PubMed ID: 33760879
    [Abstract] [Full Text] [Related]

  • 14. Structure and molecular mechanism of a functional form of pneumolysin: a cholesterol-dependent cytolysin from Streptococcus pneumoniae.
    Kelly SJ, Jedrzejas MJ.
    J Struct Biol; 2000 Oct 02; 132(1):72-81. PubMed ID: 11121308
    [Abstract] [Full Text] [Related]

  • 15. Studies on the structure and mechanism of a bacterial protein toxin by analytical ultracentrifugation and small-angle neutron scattering.
    Gilbert RJ, Heenan RK, Timmins PA, Gingles NA, Mitchell TJ, Rowe AJ, Rossjohn J, Parker MW, Andrew PW, Byron O.
    J Mol Biol; 1999 Nov 12; 293(5):1145-60. PubMed ID: 10547292
    [Abstract] [Full Text] [Related]

  • 16. Role of astroglial Connexin 43 in pneumolysin cytotoxicity and during pneumococcal meningitis.
    Bello C, Smail Y, Sainte-Rose V, Podglajen I, Gilbert A, Moreira V, Chrétien F, Cohen Salmon M, Tran Van Nhieu G.
    PLoS Pathog; 2020 Dec 12; 16(12):e1009152. PubMed ID: 33370401
    [Abstract] [Full Text] [Related]

  • 17. Heterogeneity in pneumolysin expression governs the fate of Streptococcus pneumoniae during blood-brain barrier trafficking.
    Surve MV, Bhutda S, Datey A, Anil A, Rawat S, Pushpakaran A, Singh D, Kim KS, Chakravortty D, Banerjee A.
    PLoS Pathog; 2018 Jul 12; 14(7):e1007168. PubMed ID: 30011336
    [Abstract] [Full Text] [Related]

  • 18. Ca²⁺-dependent repair of pneumolysin pores: A new paradigm for host cellular defense against bacterial pore-forming toxins.
    Wolfmeier H, Schoenauer R, Atanassoff AP, Neill DR, Kadioglu A, Draeger A, Babiychuk EB.
    Biochim Biophys Acta; 2015 Sep 12; 1853(9):2045-54. PubMed ID: 25219550
    [Abstract] [Full Text] [Related]

  • 19. Formation of pre-pore complexes of pneumolysin is accompanied by a decrease in short-range order of lipid molecules throughout vesicle bilayers.
    Faraj BHA, Collard L, Cliffe R, Blount LA, Lonnen R, Wallis R, Andrew PW, Hudson AJ.
    Sci Rep; 2020 Mar 12; 10(1):4585. PubMed ID: 32165654
    [Abstract] [Full Text] [Related]

  • 20. Estimates of differential toxin expression governing heterogeneous intracellular lifespans of Streptococcus pneumoniae.
    Santra S, Nayak I, Paladhi A, Das D, Banerjee A.
    J Cell Sci; 2024 Feb 15; 137(4):. PubMed ID: 38411297
    [Abstract] [Full Text] [Related]

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