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Journal Abstract Search

167 related items for PubMed ID: 23226420

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  • 4. Mechanism of action of a novel human ether-a-go-go-related gene channel activator.
    Casis O, Olesen SP, Sanguinetti MC.
    Mol Pharmacol; 2006 Feb; 69(2):658-65. PubMed ID: 16284303
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  • 5. The human ether-a-go-go-related gene activator NS1643 enhances epilepsy-associated KCNQ channels.
    Li P, Chen X, Zhang Q, Zheng Y, Jiang H, Yang H, Gao Z.
    J Pharmacol Exp Ther; 2014 Dec; 351(3):596-604. PubMed ID: 25232191
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  • 7. Potent activation of large-conductance Ca2+-activated K+ channels by the diphenylurea 1,3-bis-[2-hydroxy-5-(trifluoromethyl)phenyl]urea (NS1643) in pituitary tumor (GH3) cells.
    Wu SN, Peng H, Chen BS, Wang YJ, Wu PY, Lin MW.
    Mol Pharmacol; 2008 Dec; 74(6):1696-704. PubMed ID: 18809671
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  • 9. Kinetic model for NS1643 drug activation of WT and L529I variants of Kv11.1 (hERG1) potassium channel.
    Perissinotti LL, Guo J, De Biase PM, Clancy CE, Duff HJ, Noskov SY.
    Biophys J; 2015 Mar 24; 108(6):1414-1424. PubMed ID: 25809254
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  • 10. Activation of ERG2 potassium channels by the diphenylurea NS1643.
    Elmedyb P, Olesen SP, Grunnet M.
    Neuropharmacology; 2007 Aug 24; 53(2):283-94. PubMed ID: 17610913
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  • 11. Effects of Temperature on Heteromeric Kv11.1a/1b and Kv11.3 Channels.
    Mauerhöfer M, Bauer CK.
    Biophys J; 2016 Aug 09; 111(3):504-523. PubMed ID: 27508435
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  • 12. Probing the binding sites and mechanisms of action of two human ether-a-go-go-related gene channel activators, 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643) and 2-[2-(3,4-dichloro-phenyl)-2,3-dihydro-1H-isoindol-5-ylamino]-nicotinic acid (PD307243).
    Xu X, Recanatini M, Roberti M, Tseng GN.
    Mol Pharmacol; 2008 Jun 09; 73(6):1709-21. PubMed ID: 18372399
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  • 14. NS1643 interacts around L529 of hERG to alter voltage sensor movement on the path to activation.
    Guo J, Cheng YM, Lees-Miller JP, Perissinotti LL, Claydon TW, Hull CM, Thouta S, Roach DE, Durdagi S, Noskov SY, Duff HJ.
    Biophys J; 2015 Mar 24; 108(6):1400-1413. PubMed ID: 25809253
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  • 15. Structure-guided topographic mapping and mutagenesis to elucidate binding sites for the human ether-a-go-go-related gene 1 potassium channel (KCNH2) activator NS1643.
    Durdagi S, Guo J, Lees-Miller JP, Noskov SY, Duff HJ.
    J Pharmacol Exp Ther; 2012 Aug 24; 342(2):441-52. PubMed ID: 22573844
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  • 16. Computational analysis of the effects of the hERG channel opener NS1643 in a human ventricular cell model.
    Peitersen T, Grunnet M, Benson AP, Holden AV, Holstein-Rathlou NH, Olesen SP.
    Heart Rhythm; 2008 May 24; 5(5):734-41. PubMed ID: 18452879
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  • 17. Pharmacological activation of Kv11.1 in transgenic long QT-1 rabbits.
    Bentzen BH, Bahrke S, Wu K, Larsen AP, Odening KE, Franke G, Storm vańs Gravesande K, Biermann J, Peng X, Koren G, Zehender M, Bode C, Grunnet M, Brunner M.
    J Cardiovasc Pharmacol; 2011 Feb 24; 57(2):223-30. PubMed ID: 21135701
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  • 18. Pharmacological rescue of hERG currents carried out by G604S and wide type hERG co-expression.
    Huo J, Zhang A, Guo X, Qiang H, Liu P, Bai L, Ma A.
    Clin Exp Pharmacol Physiol; 2016 Sep 24; 43(9):851-61. PubMed ID: 27199074
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  • 19. Enhancement of HERG K+ currents by Cd2+ destabilization of the inactivated state.
    Johnson JP, Balser JR, Bennett PB.
    Biophys J; 1999 Nov 24; 77(5):2534-41. PubMed ID: 10545354
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