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Journal Abstract Search

141 related items for PubMed ID: 23232060

  • 1. Discovery of 4-phenyl-2-phenylaminopyridine based TNIK inhibitors.
    Ho KK, Parnell KM, Yuan Y, Xu Y, Kultgen SG, Hamblin S, Hendrickson TF, Luo B, Foulks JM, McCullar MV, Kanner SB.
    Bioorg Med Chem Lett; 2013 Jan 15; 23(2):569-73. PubMed ID: 23232060
    [Abstract] [Full Text] [Related]

  • 2. Traf2- and Nck-interacting kinase is essential for Wnt signaling and colorectal cancer growth.
    Shitashige M, Satow R, Jigami T, Aoki K, Honda K, Shibata T, Ono M, Hirohashi S, Yamada T.
    Cancer Res; 2010 Jun 15; 70(12):5024-33. PubMed ID: 20530691
    [Abstract] [Full Text] [Related]

  • 3. Discovery of 3,4-Dihydrobenzo[f][1,4]oxazepin-5(2H)-one Derivatives as a New Class of Selective TNIK Inhibitors and Evaluation of Their Anti-Colorectal Cancer Effects.
    Li Y, Zhang L, Yang R, Qiao Z, Wu M, Huang C, Tian C, Luo X, Yang W, Zhang Y, Li L, Yang S.
    J Med Chem; 2022 Feb 10; 65(3):1786-1807. PubMed ID: 34985886
    [Abstract] [Full Text] [Related]

  • 4. Synergistic inhibition effect of TNIK inhibitor KY-05009 and receptor tyrosine kinase inhibitor dovitinib on IL-6-induced proliferation and Wnt signaling pathway in human multiple myeloma cells.
    Lee Y, Jung JI, Park KY, Kim SA, Kim J.
    Oncotarget; 2017 Jun 20; 8(25):41091-41101. PubMed ID: 28467797
    [Abstract] [Full Text] [Related]

  • 5. TNIK inhibition abrogates colorectal cancer stemness.
    Masuda M, Uno Y, Ohbayashi N, Ohata H, Mimata A, Kukimoto-Niino M, Moriyama H, Kashimoto S, Inoue T, Goto N, Okamoto K, Shirouzu M, Sawa M, Yamada T.
    Nat Commun; 2016 Aug 26; 7():12586. PubMed ID: 27562646
    [Abstract] [Full Text] [Related]

  • 6. Structural Insight into TNIK Inhibition.
    Kukimoto-Niino M, Shirouzu M, Yamada T.
    Int J Mol Sci; 2022 Oct 27; 23(21):. PubMed ID: 36361804
    [Abstract] [Full Text] [Related]

  • 7. Emergence of TNIK inhibitors in cancer therapeutics.
    Yamada T, Masuda M.
    Cancer Sci; 2017 May 27; 108(5):818-823. PubMed ID: 28208209
    [Abstract] [Full Text] [Related]

  • 8. Therapeutic targets in the Wnt signaling pathway: Feasibility of targeting TNIK in colorectal cancer.
    Masuda M, Sawa M, Yamada T.
    Pharmacol Ther; 2015 Dec 27; 156():1-9. PubMed ID: 26542362
    [Abstract] [Full Text] [Related]

  • 9. Traf2- and Nck-interacting kinase (TNIK) is involved in the anti-cancer mechanism of dovitinib in human multiple myeloma IM-9 cells.
    Chon HJ, Lee Y, Bae KJ, Byun BJ, Kim SA, Kim J.
    Amino Acids; 2016 Jul 27; 48(7):1591-9. PubMed ID: 26995282
    [Abstract] [Full Text] [Related]

  • 10. The kinase TNIK is an essential activator of Wnt target genes.
    Mahmoudi T, Li VS, Ng SS, Taouatas N, Vries RG, Mohammed S, Heck AJ, Clevers H.
    EMBO J; 2009 Nov 04; 28(21):3329-40. PubMed ID: 19816403
    [Abstract] [Full Text] [Related]

  • 11. Fragment growth-based discovery of novel TNIK inhibitors for the treatment of colorectal cancer.
    Teng Y, Wu R, Bo W, Tang M, Wang T, Cui X, Li Y, Zhang C, Ma Z, Fu Z, Xu Q, Liu J, Chen L.
    Eur J Med Chem; 2024 Mar 15; 268():116240. PubMed ID: 38422698
    [Abstract] [Full Text] [Related]

  • 12. Nuclear expression of phosphorylated TRAF2- and NCK-interacting kinase in hepatocellular carcinoma is associated with poor prognosis.
    Jin J, Jung HY, Wang Y, Xie J, Yeom YI, Jang JJ, Lee KB.
    Pathol Res Pract; 2014 Oct 15; 210(10):621-7. PubMed ID: 25160513
    [Abstract] [Full Text] [Related]

  • 13. Discovery of benzo[d]oxazol-2(3H)-one derivatives as a new class of TNIK inhibitors for the treatment of colorectal cancer.
    Luo X, Yang R, Li Y, Zhang L, Yang S, Li L.
    Bioorg Med Chem Lett; 2022 Jul 01; 67():128745. PubMed ID: 35447345
    [Abstract] [Full Text] [Related]

  • 14. Comprehensive Modeling and Discovery of Mebendazole as a Novel TRAF2- and NCK-interacting Kinase Inhibitor.
    Tan Z, Chen L, Zhang S.
    Sci Rep; 2016 Sep 21; 6():33534. PubMed ID: 27650168
    [Abstract] [Full Text] [Related]

  • 15. Traf2- and Nck-interacting kinase is essential for canonical Wnt signaling in Xenopus axis formation.
    Satow R, Shitashige M, Jigami T, Honda K, Ono M, Hirohashi S, Yamada T.
    J Biol Chem; 2010 Aug 20; 285(34):26289-94. PubMed ID: 20566648
    [Abstract] [Full Text] [Related]

  • 16. Direct conversion of osteosarcoma to adipocytes by targeting TNIK.
    Hirozane T, Masuda M, Sugano T, Sekita T, Goto N, Aoyama T, Sakagami T, Uno Y, Moriyama H, Sawa M, Asano N, Nakamura M, Matsumoto M, Nakayama R, Kondo T, Kawai A, Kobayashi E, Yamada T.
    JCI Insight; 2021 Feb 08; 6(3):. PubMed ID: 33400690
    [Abstract] [Full Text] [Related]

  • 17. Discovery of new aminopyrimidine-based phosphoinositide 3-kinase beta (PI3Kβ) inhibitors with selectivity over PI3Kα.
    Kim J, Hong S, Hong S.
    Bioorg Med Chem Lett; 2011 Dec 01; 21(23):6977-81. PubMed ID: 22030027
    [Abstract] [Full Text] [Related]

  • 18. Discovery of novel 2-aminopyridine-3-carboxamides as c-Met kinase inhibitors.
    Zhang D, Ai J, Liang Z, Li C, Peng X, Ji Y, Jiang H, Geng M, Luo C, Liu H.
    Bioorg Med Chem; 2012 Sep 01; 20(17):5169-80. PubMed ID: 22863529
    [Abstract] [Full Text] [Related]

  • 19. Computational study on new natural compound inhibitors of Traf2 and Nck-interacting kinase (TNIK).
    Ma L, Li R, Yao Z, Wang B, Liu Y, Liu C, Wang H, Chen S, Sun D.
    Aging (Albany NY); 2022 Oct 25; 14(20):8394-8410. PubMed ID: 36287174
    [Abstract] [Full Text] [Related]

  • 20. Identification and characterisation of 2-aminopyridine inhibitors of checkpoint kinase 2.
    Hilton S, Naud S, Caldwell JJ, Boxall K, Burns S, Anderson VE, Antoni L, Allen CE, Pearl LH, Oliver AW, Wynne Aherne G, Garrett MD, Collins I.
    Bioorg Med Chem; 2010 Jan 15; 18(2):707-18. PubMed ID: 20022510
    [Abstract] [Full Text] [Related]

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