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Journal Abstract Search

229 related items for PubMed ID: 23237384

  • 1. Sulfonylureas have antifungal activity and are potent inhibitors of Candida albicans acetohydroxyacid synthase.
    Lee YT, Cui CJ, Chow EW, Pue N, Lonhienne T, Wang JG, Fraser JA, Guddat LW.
    J Med Chem; 2013 Jan 10; 56(1):210-9. PubMed ID: 23237384
    [Abstract] [Full Text] [Related]

  • 2. Chemical preparation, biological evaluation and 3D-QSAR of ethoxysulfuron derivatives as novel antifungal agents targeting acetohydroxyacid synthase.
    Wu RJ, Ren T, Gao JY, Wang L, Yu Q, Yao Z, Song GQ, Ruan WB, Niu CW, Song FH, Zhang LX, Li M, Wang JG.
    Eur J Med Chem; 2019 Jan 15; 162():348-363. PubMed ID: 30448420
    [Abstract] [Full Text] [Related]

  • 3. Commercial AHAS-inhibiting herbicides are promising drug leads for the treatment of human fungal pathogenic infections.
    Garcia MD, Chua SMH, Low YS, Lee YT, Agnew-Francis K, Wang JG, Nouwens A, Lonhienne T, Williams CM, Fraser JA, Guddat LW.
    Proc Natl Acad Sci U S A; 2018 Oct 09; 115(41):E9649-E9658. PubMed ID: 30249642
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  • 4. Design, synthesis and herbicidal activity study of aryl 2,6-disubstituted sulfonylureas as potent acetohydroxyacid synthase inhibitors.
    Wei W, Zhou S, Cheng D, Li Y, Liu J, Xie Y, Li Y, Li Z.
    Bioorg Med Chem Lett; 2017 Aug 01; 27(15):3365-3369. PubMed ID: 28610985
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  • 5. Structure-activity relationships for a new family of sulfonylurea herbicides.
    Wang JG, Li ZM, Ma N, Wang BL, Jiang L, Pang SS, Lee YT, Guddat LW, Duggleby RG.
    J Comput Aided Mol Des; 2005 Nov 01; 19(11):801-20. PubMed ID: 16374672
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  • 7. Comprehensive understanding of acetohydroxyacid synthase inhibition by different herbicide families.
    Garcia MD, Nouwens A, Lonhienne TG, Guddat LW.
    Proc Natl Acad Sci U S A; 2017 Feb 14; 114(7):E1091-E1100. PubMed ID: 28137884
    [Abstract] [Full Text] [Related]

  • 8. Acetohydroxyacid synthase: a target for antimicrobial drug discovery.
    Pue N, Guddat LW.
    Curr Pharm Des; 2014 Feb 14; 20(5):740-53. PubMed ID: 23688082
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  • 10. Biochemical characterization and evaluation of potent inhibitors of the Pseudomonas aeruginosa PA01 acetohydroxyacid synthase.
    Cho JH, Lee MY, Baig IA, Ha NR, Kim J, Yoon MY.
    Biochimie; 2013 Jul 14; 95(7):1411-21. PubMed ID: 23523771
    [Abstract] [Full Text] [Related]

  • 11. Triazolopyrimidine herbicides are potent inhibitors of Aspergillus fumigatus acetohydroxyacid synthase and potential antifungal drug leads.
    Low YS, Garcia MD, Lonhienne T, Fraser JA, Schenk G, Guddat LW.
    Sci Rep; 2021 Oct 26; 11(1):21055. PubMed ID: 34702838
    [Abstract] [Full Text] [Related]

  • 12. Design and synthesis of novel imidazole-substituted dipeptide amides as potent and selective inhibitors of Candida albicans myristoylCoA:protein N-myristoyltransferase and identification of related tripeptide inhibitors with mechanism-based antifungal activity.
    Devadas B, Freeman SK, Zupec ME, Lu HF, Nagarajan SR, Kishore NS, Lodge JK, Kuneman DW, McWherter CA, Vinjamoori DV, Getman DP, Gordon JI, Sikorski JA.
    J Med Chem; 1997 Aug 01; 40(16):2609-25. PubMed ID: 9258368
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  • 13. Synthesis, crystal structure and biological evaluation of substituted quinazolinone benzoates as novel antituberculosis agents targeting acetohydroxyacid synthase.
    Lu W, Baig IA, Sun HJ, Cui CJ, Guo R, Jung IP, Wang D, Dong M, Yoon MY, Wang JG.
    Eur J Med Chem; 2015 Apr 13; 94():298-305. PubMed ID: 25771108
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  • 16. Crystal structures of two novel sulfonylurea herbicides in complex with Arabidopsis thaliana acetohydroxyacid synthase.
    Wang JG, Lee PK, Dong YH, Pang SS, Duggleby RG, Li ZM, Guddat LW.
    FEBS J; 2009 Mar 13; 276(5):1282-90. PubMed ID: 19187232
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  • 19. Chemical synthesis, in vitro acetohydroxyacid synthase (AHAS) inhibition, herbicidal activity, and computational studies of isatin derivatives.
    Wang J, Tan H, Li Y, Ma Y, Li Z, Guddat LW.
    J Agric Food Chem; 2011 Sep 28; 59(18):9892-900. PubMed ID: 21838297
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  • 20. How important is the synclinal conformation of sulfonylureas to explain the inhibition of AHAS: a theoretical study.
    Jaña GA, Delgado EJ, Medina FE.
    J Chem Inf Model; 2014 Mar 24; 54(3):926-32. PubMed ID: 24548139
    [Abstract] [Full Text] [Related]

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