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317 related items for PubMed ID: 23239349

  • 1. Double receptor anchorage of botulinum neurotoxins accounts for their exquisite neurospecificity.
    Rummel A.
    Curr Top Microbiol Immunol; 2013; 364():61-90. PubMed ID: 23239349
    [Abstract] [Full Text] [Related]

  • 2. Two Feet on the Membrane: Uptake of Clostridial Neurotoxins.
    Rummel A.
    Curr Top Microbiol Immunol; 2017; 406():1-37. PubMed ID: 27921176
    [Abstract] [Full Text] [Related]

  • 3. Botulinum neurotoxins C, E and F bind gangliosides via a conserved binding site prior to stimulation-dependent uptake with botulinum neurotoxin F utilising the three isoforms of SV2 as second receptor.
    Rummel A, Häfner K, Mahrhold S, Darashchonak N, Holt M, Jahn R, Beermann S, Karnath T, Bigalke H, Binz T.
    J Neurochem; 2009 Sep; 110(6):1942-54. PubMed ID: 19650874
    [Abstract] [Full Text] [Related]

  • 4. Botulinum neurotoxin D uses synaptic vesicle protein SV2 and gangliosides as receptors.
    Peng L, Tepp WH, Johnson EA, Dong M.
    PLoS Pathog; 2011 Mar; 7(3):e1002008. PubMed ID: 21483489
    [Abstract] [Full Text] [Related]

  • 5. Glycosylated SV2A and SV2B mediate the entry of botulinum neurotoxin E into neurons.
    Dong M, Liu H, Tepp WH, Johnson EA, Janz R, Chapman ER.
    Mol Biol Cell; 2008 Dec; 19(12):5226-37. PubMed ID: 18815274
    [Abstract] [Full Text] [Related]

  • 6. Glycosylated SV2 and gangliosides as dual receptors for botulinum neurotoxin serotype F.
    Fu Z, Chen C, Barbieri JT, Kim JJ, Baldwin MR.
    Biochemistry; 2009 Jun 23; 48(24):5631-41. PubMed ID: 19476346
    [Abstract] [Full Text] [Related]

  • 7. Botulinum neurotoxin serotype D attacks neurons via two carbohydrate-binding sites in a ganglioside-dependent manner.
    Strotmeier J, Lee K, Völker AK, Mahrhold S, Zong Y, Zeiser J, Zhou J, Pich A, Bigalke H, Binz T, Rummel A, Jin R.
    Biochem J; 2010 Oct 15; 431(2):207-16. PubMed ID: 20704566
    [Abstract] [Full Text] [Related]

  • 8. SV2 is the protein receptor for botulinum neurotoxin A.
    Dong M, Yeh F, Tepp WH, Dean C, Johnson EA, Janz R, Chapman ER.
    Science; 2006 Apr 28; 312(5773):592-6. PubMed ID: 16543415
    [Abstract] [Full Text] [Related]

  • 9. Botulinum Neurotoxin Serotype A Recognizes Its Protein Receptor SV2 by a Different Mechanism than Botulinum Neurotoxin B Synaptotagmin.
    Weisemann J, Stern D, Mahrhold S, Dorner BG, Rummel A.
    Toxins (Basel); 2016 May 17; 8(5):. PubMed ID: 27196927
    [Abstract] [Full Text] [Related]

  • 10. Exchanging the minimal cell binding fragments of tetanus neurotoxin in botulinum neurotoxin A and B impacts their toxicity at the neuromuscular junction and central neurons.
    Höltje M, Schulze S, Strotmeier J, Mahrhold S, Richter K, Binz T, Bigalke H, Ahnert-Hilger G, Rummel A.
    Toxicon; 2013 Dec 01; 75():108-21. PubMed ID: 23817019
    [Abstract] [Full Text] [Related]

  • 11. Botulinum neurotoxin D-C uses synaptotagmin I and II as receptors, and human synaptotagmin II is not an effective receptor for type B, D-C and G toxins.
    Peng L, Berntsson RP, Tepp WH, Pitkin RM, Johnson EA, Stenmark P, Dong M.
    J Cell Sci; 2012 Jul 01; 125(Pt 13):3233-42. PubMed ID: 22454523
    [Abstract] [Full Text] [Related]

  • 12. Identification of the SV2 protein receptor-binding site of botulinum neurotoxin type E.
    Mahrhold S, Strotmeier J, Garcia-Rodriguez C, Lou J, Marks JD, Rummel A, Binz T.
    Biochem J; 2013 Jul 01; 453(1):37-47. PubMed ID: 23621114
    [Abstract] [Full Text] [Related]

  • 13. Botulinum neurotoxin serotype C associates with dual ganglioside receptors to facilitate cell entry.
    Karalewitz AP, Fu Z, Baldwin MR, Kim JJ, Barbieri JT.
    J Biol Chem; 2012 Nov 23; 287(48):40806-16. PubMed ID: 23027864
    [Abstract] [Full Text] [Related]

  • 14. Association of botulinum neurotoxin serotypes a and B with synaptic vesicle protein complexes.
    Baldwin MR, Barbieri JT.
    Biochemistry; 2007 Mar 20; 46(11):3200-10. PubMed ID: 17311420
    [Abstract] [Full Text] [Related]

  • 15. Tetanus toxin and botulinum toxin a utilize unique mechanisms to enter neurons of the central nervous system.
    Blum FC, Chen C, Kroken AR, Barbieri JT.
    Infect Immun; 2012 May 20; 80(5):1662-9. PubMed ID: 22392932
    [Abstract] [Full Text] [Related]

  • 16. Synaptotagmins I and II act as nerve cell receptors for botulinum neurotoxin G.
    Rummel A, Karnath T, Henke T, Bigalke H, Binz T.
    J Biol Chem; 2004 Jul 16; 279(29):30865-70. PubMed ID: 15123599
    [Abstract] [Full Text] [Related]

  • 17. Exchange of the H(CC) domain mediating double receptor recognition improves the pharmacodynamic properties of botulinum neurotoxin.
    Rummel A, Mahrhold S, Bigalke H, Binz T.
    FEBS J; 2011 Dec 16; 278(23):4506-15. PubMed ID: 21624052
    [Abstract] [Full Text] [Related]

  • 18. Synaptic vesicle proteins: targets and routes for botulinum neurotoxins.
    Ahnert-Hilger G, Münster-Wandowski A, Höltje M.
    Curr Top Microbiol Immunol; 2013 Dec 16; 364():159-77. PubMed ID: 23239353
    [Abstract] [Full Text] [Related]

  • 19. Association of botulinum neurotoxins with synaptic vesicle protein complexes.
    Baldwin MR, Barbieri JT.
    Toxicon; 2009 Oct 16; 54(5):570-4. PubMed ID: 19362106
    [Abstract] [Full Text] [Related]

  • 20. Only the complex N559-glycan in the synaptic vesicle glycoprotein 2C mediates high affinity binding to botulinum neurotoxin serotype A1.
    Mahrhold S, Bergström T, Stern D, Dorner BG, Åstot C, Rummel A.
    Biochem J; 2016 Sep 01; 473(17):2645-54. PubMed ID: 27313224
    [Abstract] [Full Text] [Related]

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