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Journal Abstract Search

342 related items for PubMed ID: 23247844

  • 1. FOXO1-mediated upregulation of pyruvate dehydrogenase kinase-4 (PDK4) decreases glucose oxidation and impairs right ventricular function in pulmonary hypertension: therapeutic benefits of dichloroacetate.
    Piao L, Sidhu VK, Fang YH, Ryan JJ, Parikh KS, Hong Z, Toth PT, Morrow E, Kutty S, Lopaschuk GD, Archer SL.
    J Mol Med (Berl); 2013 Mar; 91(3):333-46. PubMed ID: 23247844
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  • 2. The inhibition of pyruvate dehydrogenase kinase improves impaired cardiac function and electrical remodeling in two models of right ventricular hypertrophy: resuscitating the hibernating right ventricle.
    Piao L, Fang YH, Cadete VJ, Wietholt C, Urboniene D, Toth PT, Marsboom G, Zhang HJ, Haber I, Rehman J, Lopaschuk GD, Archer SL.
    J Mol Med (Berl); 2010 Jan; 88(1):47-60. PubMed ID: 19949938
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  • 3. FoxO1 regulates myocardial glucose oxidation rates via transcriptional control of pyruvate dehydrogenase kinase 4 expression.
    Gopal K, Saleme B, Al Batran R, Aburasayn H, Eshreif A, Ho KL, Ma WK, Almutairi M, Eaton F, Gandhi M, Park EA, Sutendra G, Ussher JR.
    Am J Physiol Heart Circ Physiol; 2017 Sep 01; 313(3):H479-H490. PubMed ID: 28687587
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  • 4. Epigenetic Metabolic Reprogramming of Right Ventricular Fibroblasts in Pulmonary Arterial Hypertension: A Pyruvate Dehydrogenase Kinase-Dependent Shift in Mitochondrial Metabolism Promotes Right Ventricular Fibrosis.
    Tian L, Wu D, Dasgupta A, Chen KH, Mewburn J, Potus F, Lima PDA, Hong Z, Zhao YY, Hindmarch CCT, Kutty S, Provencher S, Bonnet S, Sutendra G, Archer SL.
    Circ Res; 2020 Jun 05; 126(12):1723-1745. PubMed ID: 32216531
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  • 5. Therapeutic inhibition of fatty acid oxidation in right ventricular hypertrophy: exploiting Randle's cycle.
    Fang YH, Piao L, Hong Z, Toth PT, Marsboom G, Bache-Wiig P, Rehman J, Archer SL.
    J Mol Med (Berl); 2012 Jan 05; 90(1):31-43. PubMed ID: 21874543
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  • 11. Bawei Chenxiang Wan ameliorates right ventricular hypertrophy in rats with high altitude heart disease by SIRT3-HIF1α-PDK/PDH signaling pathway improving fatty acid and glucose metabolism.
    Han Y, Li S, Zhang Z, Ning X, Wu J, Zhang X.
    BMC Complement Med Ther; 2024 May 15; 24(1):190. PubMed ID: 38750550
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  • 13. An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human pulmonary arterial hypertension.
    Bonnet S, Michelakis ED, Porter CJ, Andrade-Navarro MA, Thébaud B, Bonnet S, Haromy A, Harry G, Moudgil R, McMurtry MS, Weir EK, Archer SL.
    Circulation; 2006 Jun 06; 113(22):2630-41. PubMed ID: 16735674
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  • 17. Chronic inhibition of pyruvate dehydrogenase in heart triggers an adaptive metabolic response.
    Chambers KT, Leone TC, Sambandam N, Kovacs A, Wagg CS, Lopaschuk GD, Finck BN, Kelly DP.
    J Biol Chem; 2011 Apr 01; 286(13):11155-62. PubMed ID: 21321124
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  • 20. The increase in cardiac pyruvate dehydrogenase kinase-4 after short-term dexamethasone is controlled by an Akt-p38-forkhead box other factor-1 signaling axis.
    Puthanveetil P, Wang Y, Wang F, Kim MS, Abrahani A, Rodrigues B.
    Endocrinology; 2010 May 01; 151(5):2306-18. PubMed ID: 20181797
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