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399 related items for PubMed ID: 23250396

  • 1. IGFBP7 binds to the IGF-1 receptor and blocks its activation by insulin-like growth factors.
    Evdokimova V, Tognon CE, Benatar T, Yang W, Krutikov K, Pollak M, Sorensen PH, Seth A.
    Sci Signal; 2012 Dec 18; 5(255):ra92. PubMed ID: 23250396
    [Abstract] [Full Text] [Related]

  • 2. Differential activation of insulin receptor substrates 1 and 2 by insulin-like growth factor-activated insulin receptors.
    Denley A, Carroll JM, Brierley GV, Cosgrove L, Wallace J, Forbes B, Roberts CT.
    Mol Cell Biol; 2007 May 18; 27(10):3569-77. PubMed ID: 17325037
    [Abstract] [Full Text] [Related]

  • 3. A chimeric humanized single-chain antibody against the type I insulin-like growth factor (IGF) receptor renders breast cancer cells refractory to the mitogenic effects of IGF-I.
    Sachdev D, Li SL, Hartell JS, Fujita-Yamaguchi Y, Miller JS, Yee D.
    Cancer Res; 2003 Feb 01; 63(3):627-35. PubMed ID: 12566306
    [Abstract] [Full Text] [Related]

  • 4. Affinity for the insulin-like growth factor-II (IGF-II) receptor inhibits autocrine IGF-II activity in MCF-7 breast cancer cells.
    Ellis MJ, Leav BA, Yang Z, Rasmussen A, Pearce A, Zweibel JA, Lippman ME, Cullen KJ.
    Mol Endocrinol; 1996 Mar 01; 10(3):286-97. PubMed ID: 8833657
    [Abstract] [Full Text] [Related]

  • 5. Role of the insulin-like growth factor system on an estrogen-dependent cancer phenotype in the MCF-7 human breast cancer cell line.
    Bradley LM, Gierthy JF, Pentecost BT.
    J Steroid Biochem Mol Biol; 2008 Mar 01; 109(1-2):185-96. PubMed ID: 18337089
    [Abstract] [Full Text] [Related]

  • 6. IGFBP7 reduces breast tumor growth by induction of senescence and apoptosis pathways.
    Benatar T, Yang W, Amemiya Y, Evdokimova V, Kahn H, Holloway C, Seth A.
    Breast Cancer Res Treat; 2012 Jun 01; 133(2):563-73. PubMed ID: 21997538
    [Abstract] [Full Text] [Related]

  • 7. Physiologic IGFBP7 levels prolong IGF1R activation in acute lymphoblastic leukemia.
    Artico LL, Laranjeira ABA, Campos LW, Corrêa JR, Zenatti PP, Carvalheira JBC, Brambilla SR, Nowill AE, Brandalise SR, Yunes JA.
    Blood Adv; 2021 Sep 28; 5(18):3633-3646. PubMed ID: 34438446
    [Abstract] [Full Text] [Related]

  • 8. Insulin-like growth factors inhibit dendritic cell-mediated anti-tumor immunity through regulating ERK1/2 phosphorylation and p38 dephosphorylation.
    Huang CT, Chang MC, Chen YL, Chen TC, Chen CA, Cheng WF.
    Cancer Lett; 2015 Apr 01; 359(1):117-26. PubMed ID: 25592043
    [Abstract] [Full Text] [Related]

  • 9. TGF-β-induced expression of IGFBP-3 regulates IGF1R signaling in human osteosarcoma cells.
    Schedlich LJ, Yenson VM, Baxter RC.
    Mol Cell Endocrinol; 2013 Sep 05; 377(1-2):56-64. PubMed ID: 23831640
    [Abstract] [Full Text] [Related]

  • 10. Diversity of insulin and IGF signaling in breast cancer: Implications for therapy.
    Lero MW, Shaw LM.
    Mol Cell Endocrinol; 2021 May 01; 527():111213. PubMed ID: 33607269
    [Abstract] [Full Text] [Related]

  • 11. Down-regulation of type I insulin-like growth factor receptor increases sensitivity of breast cancer cells to insulin.
    Zhang H, Pelzer AM, Kiang DT, Yee D.
    Cancer Res; 2007 Jan 01; 67(1):391-7. PubMed ID: 17210722
    [Abstract] [Full Text] [Related]

  • 12. IGF-II is up-regulated and myofibres are hypertrophied in regenerating soleus of mice lacking FGF6.
    Armand AS, Lécolle S, Launay T, Pariset C, Fiore F, Della Gaspera B, Birnbaum D, Chanoine C, Charbonnier F.
    Exp Cell Res; 2004 Jul 01; 297(1):27-38. PubMed ID: 15194422
    [Abstract] [Full Text] [Related]

  • 13. An integrin binding-defective mutant of insulin-like growth factor-1 (R36E/R37E IGF1) acts as a dominant-negative antagonist of the IGF1 receptor (IGF1R) and suppresses tumorigenesis but still binds to IGF1R.
    Fujita M, Ieguchi K, Cedano-Prieto DM, Fong A, Wilkerson C, Chen JQ, Wu M, Lo SH, Cheung AT, Wilson MD, Cardiff RD, Borowsky AD, Takada YK, Takada Y.
    J Biol Chem; 2013 Jul 05; 288(27):19593-603. PubMed ID: 23696648
    [Abstract] [Full Text] [Related]

  • 14. GIPC mediates the generation of reactive oxygen species and the regulation of cancer cell proliferation by insulin-like growth factor-1/IGF-1R signaling.
    Choi JS, Paek AR, Kim SY, You HJ.
    Cancer Lett; 2010 Aug 28; 294(2):254-63. PubMed ID: 20206441
    [Abstract] [Full Text] [Related]

  • 15. Estrogen Receptor-β Up-Regulates IGF1R Expression and Activity to Inhibit Apoptosis and Increase Growth of Medulloblastoma.
    Cookman CJ, Belcher SM.
    Endocrinology; 2015 Jul 28; 156(7):2395-408. PubMed ID: 25885794
    [Abstract] [Full Text] [Related]

  • 16. Insulin-like growth factor binding protein-4 and -5 modulate ligand-dependent estrogen receptor-α activation in breast cancer cells in an IGF-independent manner.
    Hermani A, Shukla A, Medunjanin S, Werner H, Mayer D.
    Cell Signal; 2013 Jun 28; 25(6):1395-402. PubMed ID: 23499909
    [Abstract] [Full Text] [Related]

  • 17. A fully human monoclonal antibody to the insulin-like growth factor I receptor blocks ligand-dependent signaling and inhibits human tumor growth in vivo.
    Burtrum D, Zhu Z, Lu D, Anderson DM, Prewett M, Pereira DS, Bassi R, Abdullah R, Hooper AT, Koo H, Jimenez X, Johnson D, Apblett R, Kussie P, Bohlen P, Witte L, Hicklin DJ, Ludwig DL.
    Cancer Res; 2003 Dec 15; 63(24):8912-21. PubMed ID: 14695208
    [Abstract] [Full Text] [Related]

  • 18. Role for membrane and secreted insulin-like growth factor-binding protein-2 in the regulation of insulin-like growth factor action in lung tumors.
    Reeve JG, Morgan J, Schwander J, Bleehen NM.
    Cancer Res; 1993 Oct 01; 53(19):4680-5. PubMed ID: 7691401
    [Abstract] [Full Text] [Related]

  • 19. Differential signaling activation by insulin and insulin-like growth factors I and II upon binding to insulin receptor isoform A.
    Sacco A, Morcavallo A, Pandini G, Vigneri R, Belfiore A.
    Endocrinology; 2009 Aug 01; 150(8):3594-602. PubMed ID: 19443570
    [Abstract] [Full Text] [Related]

  • 20. The insulin-like growth factor axis and prostate cancer: lessons from the transgenic adenocarcinoma of mouse prostate (TRAMP) model.
    Kaplan PJ, Mohan S, Cohen P, Foster BA, Greenberg NM.
    Cancer Res; 1999 May 01; 59(9):2203-9. PubMed ID: 10232609
    [Abstract] [Full Text] [Related]

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