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226 related items for PubMed ID: 2325562

  • 1. Decreased cholesterol biosynthesis in sitosterolemia with xanthomatosis: diminished mononuclear leukocyte 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and enzyme protein associated with increased low-density lipoprotein receptor function.
    Nguyen LB, Salen G, Shefer S, Tint GS, Shore V, Ness GC.
    Metabolism; 1990 Apr; 39(4):436-43. PubMed ID: 2325562
    [Abstract] [Full Text] [Related]

  • 2. Regulation of cholesterol biosynthesis in sitosterolemia: effects of lovastatin, cholestyramine, and dietary sterol restriction.
    Nguyen LB, Cobb M, Shefer S, Salen G, Ness GC, Tint GS.
    J Lipid Res; 1991 Dec; 32(12):1941-8. PubMed ID: 1816322
    [Abstract] [Full Text] [Related]

  • 3. Unexpected failure of bile acid malabsorption to stimulate cholesterol synthesis in sitosterolemia with xanthomatosis. Comparison with lovastatin.
    Nguyen L, Salen G, Shefer S, Shore V, Tint GS, Ness G.
    Arteriosclerosis; 1990 Dec; 10(2):289-97. PubMed ID: 2317163
    [Abstract] [Full Text] [Related]

  • 4. 3-Hydroxy-3-methylglutaryl-coenzyme A reductase activity is inhibited by cholesterol and up-regulated by sitosterol in sitosterolemic fibroblasts.
    Honda A, Salen G, Honda M, Batta AK, Tint GS, Xu G, Chen TS, Tanaka N, Shefer S.
    J Lab Clin Med; 2000 Feb; 135(2):174-9. PubMed ID: 10695663
    [Abstract] [Full Text] [Related]

  • 5. Down-regulation of cholesterol biosynthesis in sitosterolemia: diminished activities of acetoacetyl-CoA thiolase, 3-hydroxy-3-methylglutaryl-CoA synthase, reductase, squalene synthase, and 7-dehydrocholesterol delta7-reductase in liver and mononuclear leukocytes.
    Honda A, Salen G, Nguyen LB, Tint GS, Batta AK, Shefer S.
    J Lipid Res; 1998 Jan; 39(1):44-50. PubMed ID: 9469584
    [Abstract] [Full Text] [Related]

  • 6. A molecular defect in hepatic cholesterol biosynthesis in sitosterolemia with xanthomatosis.
    Nguyen LB, Shefer S, Salen G, Ness GC, Tint GS, Zaki FG, Rani I.
    J Clin Invest; 1990 Sep; 86(3):923-31. PubMed ID: 2394840
    [Abstract] [Full Text] [Related]

  • 7. Macrophage 3-hydroxy-3-methylglutaryl coenzyme a reductase activity in sitosterolemia: effects of increased cellular cholesterol and sitosterol concentrations.
    Nguyen LB, Salen G, Shefer S, Tint GS, Ruiz F.
    Metabolism; 2001 Oct; 50(10):1224-9. PubMed ID: 11586498
    [Abstract] [Full Text] [Related]

  • 8. Deficient ileal 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in sitosterolemia: sitosterol is not a feedback inhibitor of intestinal cholesterol biosynthesis.
    Nguyen LB, Salen G, Shefer S, Bullock J, Chen T, Tint GS, Chowdhary IR, Lerner S.
    Metabolism; 1994 Jul; 43(7):855-9. PubMed ID: 8028508
    [Abstract] [Full Text] [Related]

  • 9. In vivo regulation of human mononuclear leukocyte 3-hydroxy-3-methylglutaryl coenzyme A reductase. Decreased enzyme catalytic efficiency in familial hypercholesterolemia.
    Stacpoole PW, Bridge DM, Alvarez IM, Goldberg RB, Harwood HJ.
    J Clin Invest; 1987 Nov; 80(5):1401-8. PubMed ID: 2824560
    [Abstract] [Full Text] [Related]

  • 10. The effect of increased hepatic sitosterol on the regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and cholesterol 7 alpha-hydroxylase in the rat and sitosterolemic homozygotes.
    Shefer S, Salen G, Bullock J, Nguyen LB, Ness GC, Vhao Z, Belamarich PF, Chowdhary I, Lerner S, Batta AK.
    Hepatology; 1994 Jul; 20(1 Pt 1):213-9. PubMed ID: 8020891
    [Abstract] [Full Text] [Related]

  • 11. Lovastatin treatment inhibits sterol synthesis and induces HMG-CoA reductase activity in mononuclear leukocytes of normal subjects.
    Stone BG, Evans CD, Prigge WF, Duane WC, Gebhard RL.
    J Lipid Res; 1989 Dec; 30(12):1943-52. PubMed ID: 2621421
    [Abstract] [Full Text] [Related]

  • 12. Low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression in human mononuclear leukocytes is regulated coordinately and parallels gene expression in human liver.
    Powell EE, Kroon PA.
    J Clin Invest; 1994 May; 93(5):2168-74. PubMed ID: 8182149
    [Abstract] [Full Text] [Related]

  • 13. Sitosterolemia: exclusion of genes involved in reduced cholesterol biosynthesis.
    Patel SB, Honda A, Salen G.
    J Lipid Res; 1998 May; 39(5):1055-61. PubMed ID: 9610773
    [Abstract] [Full Text] [Related]

  • 14. In vivo regulation of human leukocyte 3-hydroxy-3-methylglutaryl coenzyme A reductase: increased enzyme protein concentration and catalytic efficiency in human leukemia and lymphoma.
    Harwood HJ, Alvarez IM, Noyes WD, Stacpoole PW.
    J Lipid Res; 1991 Aug; 32(8):1237-52. PubMed ID: 1770307
    [Abstract] [Full Text] [Related]

  • 15. Mechanism of induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase in human leukocytes.
    Fogelman AM, Seager J, Edwards PA, Popják G.
    J Biol Chem; 1977 Jan 25; 252(2):644-51. PubMed ID: 833148
    [Abstract] [Full Text] [Related]

  • 16. Enhancement of sterol synthesis by the monoterpene perillyl alcohol is unaffected by competitive 3-hydroxy-3-methylglutaryl-CoA reductase inhibition.
    Cerda SR, Wilkinson J, Branch SK, Broitman SA.
    Lipids; 1999 Jun 25; 34(6):605-15. PubMed ID: 10405975
    [Abstract] [Full Text] [Related]

  • 17. Development of a noncompetitive, solid phase, bridged biotin-avidin enzyme immunoassay for measurement of human leukocyte microsomal HMG-CoA reductase protein concentration.
    Harwood HJ, Alvarez IM, Greene YJ, Ness GC, Stacpoole PW.
    J Lipid Res; 1987 Mar 25; 28(3):292-304. PubMed ID: 3553404
    [Abstract] [Full Text] [Related]

  • 18. The effect of abnormal plasma and cellular sterol content and composition on low density lipoprotein uptake and degradation by monocytes and lymphocytes in sitosterolemia with xanthomatosis.
    Nguyen LB, Shefer S, Salen G, Horak I, Tint GS, McNamara DJ.
    Metabolism; 1988 Apr 25; 37(4):346-51. PubMed ID: 3357417
    [Abstract] [Full Text] [Related]

  • 19. Increased sitosterol absorption, decreased removal, and expanded body pools compensate for reduced cholesterol synthesis in sitosterolemia with xanthomatosis.
    Salen G, Shore V, Tint GS, Forte T, Shefer S, Horak I, Horak E, Dayal B, Nguyen L, Batta AK.
    J Lipid Res; 1989 Sep 25; 30(9):1319-30. PubMed ID: 2600539
    [Abstract] [Full Text] [Related]

  • 20. Cholesterol biosynthesis and 3-hydroxy-3-methyl-glutaryl coenzyme A reductase in cultured glial and neuronal cells. Regulation by lipoprotein and by certain free sterols.
    Volpe JJ, Hennessy SW.
    Biochim Biophys Acta; 1977 Mar 25; 486(3):408-20. PubMed ID: 856284
    [Abstract] [Full Text] [Related]

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